CY1403A - Benzazepin-2-ones - Google Patents

Benzazepin-2-ones

Info

Publication number
CY1403A
CY1403A CY140382A CY140382A CY1403A CY 1403 A CY1403 A CY 1403A CY 140382 A CY140382 A CY 140382A CY 140382 A CY140382 A CY 140382A CY 1403 A CY1403 A CY 1403A
Authority
CY
Cyprus
Prior art keywords
benzazepin
ones
Prior art date
Application number
CY140382A
Other languages
English (en)
Inventor
William Herbert Watthe Jeffrey
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CY1403A publication Critical patent/CY1403A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CY140382A 1981-08-11 1982-08-05 Benzazepin-2-ones CY1403A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29190781A 1981-08-11 1981-08-11
US31986381A 1981-11-09 1981-11-09

Publications (1)

Publication Number Publication Date
CY1403A true CY1403A (en) 1987-12-18

Family

ID=26967047

Family Applications (1)

Application Number Title Priority Date Filing Date
CY140382A CY1403A (en) 1981-08-11 1982-08-05 Benzazepin-2-ones

Country Status (22)

Country Link
EP (1) EP0072352B1 (nl)
KR (3) KR890003425B1 (nl)
AR (3) AR240806A1 (nl)
AT (1) ATE18397T1 (nl)
AU (1) AU561395B2 (nl)
CA (1) CA1196636A (nl)
CY (1) CY1403A (nl)
DD (1) DD202546A5 (nl)
DE (1) DE3269625D1 (nl)
DK (1) DK157881C (nl)
ES (6) ES8502974A1 (nl)
FI (1) FI76074C (nl)
GB (1) GB2103614B (nl)
GR (1) GR77256B (nl)
HK (1) HK93387A (nl)
HU (1) HU189628B (nl)
IE (1) IE53668B1 (nl)
IL (1) IL66501A (nl)
NL (1) NL930112I2 (nl)
NO (1) NO161558C (nl)
NZ (1) NZ201555A (nl)
PT (1) PT75395B (nl)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3242599A1 (de) * 1982-11-18 1984-05-24 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel
US4473575A (en) * 1982-07-19 1984-09-25 Ciba-Geigy Corporation 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
DE3373469D1 (en) * 1982-09-30 1987-10-15 Merck & Co Inc 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents
US4575503A (en) * 1983-02-10 1986-03-11 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4564612A (en) * 1983-04-22 1986-01-14 Takeda Chemical Industries, Ltd. Condensed, seven-membered ring compounds and their use
US4539150A (en) * 1983-06-29 1985-09-03 Mitsui Toatsu Chemicals, Inc. Benzothiazepine derivatives and their methods of preparation
JPS608284A (ja) * 1983-06-29 1985-01-17 Mitsui Toatsu Chem Inc ベンゾチアゼピン誘導体およびその製造法
AU570710B2 (en) * 1983-08-12 1988-03-24 Takeda Chemical Industries Ltd. 4-oxo-2, 3, 4, 5-tetrahydro-1, 5-benzoxazepine derivatives
US4638000A (en) * 1983-08-12 1987-01-20 Takeda Chemical Industries, Ltd. Condensed seven-membered ring compounds, their production and use
IL72523A (en) * 1983-08-12 1988-06-30 Takeda Chemical Industries Ltd 3-amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine derivatives,their production and pharmaceutical compositions containing them
CA1266647A (en) * 1984-06-26 1990-03-13 William H. Parsons Benzofused lactams useful as antihypertensive agents and as cholecystokinin antagonists
DE3586445T2 (de) * 1984-06-26 1993-01-14 Merck & Co Inc Kondensierte benzo-laktam-verbindungen und deren pharmazeutische zusammensetzungen.
EP0166357A3 (en) * 1984-06-26 1988-10-26 Merck & Co. Inc. Benzofused lactams and pharmaceutical compositions containing them
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation
DE3704661A1 (de) * 1987-02-14 1988-08-25 Hoechst Ag Annelierte azepinon- und azocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
TW197945B (nl) * 1990-11-27 1993-01-11 Hoechst Ag
GB9100028D0 (en) * 1991-01-02 1991-02-20 Ici Plc Compounds
GB9212308D0 (en) * 1992-06-10 1992-07-22 Ici Plc Therapeutic compositions
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
JPH08505374A (ja) * 1992-12-11 1996-06-11 チバ−ガイギー アクチェンゲゼルシャフト ベンズアゼピノン誘導体
GB9310075D0 (en) * 1993-05-17 1993-06-30 Fujisawa Pharmaceutical Co New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB9311948D0 (en) * 1993-06-10 1993-07-28 Zeneca Ltd Substituted nitrogen heterocycles
US5801168A (en) * 1994-06-09 1998-09-01 Zeneca Limited Substituted nitrogen heterocycles
US5597922A (en) * 1994-07-29 1997-01-28 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Glycine receptor antagonist pharmacophore
EP1229913A4 (en) * 1999-11-18 2005-01-19 Antexpharma Inc SUBSTITUTED 1-BENZAZEPINE AND THEIR DERIVATIVES
EP2256104A1 (en) 2000-12-27 2010-12-01 Merck Patent GmbH Process for the preparation of alpha-aminosubstituted carboxylic acid amides
JP2004526735A (ja) 2001-03-27 2004-09-02 ランバクシー ラボラトリーズ リミテッド ベナゼプリルの製造方法
AU2002348276A1 (en) 2001-11-16 2003-06-10 Bristol-Myers Squibb Company Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
US20050107359A1 (en) * 2002-07-26 2005-05-19 Van Der Schaaf Paul A. Crystalline polymorphic and amorphous forms of benazepril hydrochloride
KR100710548B1 (ko) * 2002-12-26 2007-04-24 에스케이 주식회사 (ｓ)-3-아미노-2,3,4,5-테트라히드로-2-옥소-1Ｈ-1-벤자제핀-1-아세트산 및 이의 에스테르 화합물의 제조방법
US7459474B2 (en) 2003-06-11 2008-12-02 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
US8080579B2 (en) 2005-10-03 2011-12-20 The Regents Of The University Of Michigan Compositions and methods for treatment of inflammatory bowel disease
US7592461B2 (en) 2005-12-21 2009-09-22 Bristol-Myers Squibb Company Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
EP2089355A2 (en) 2006-11-01 2009-08-19 Brystol-Myers Squibb Company Modulators of glucocorticoid receptor, ap-1, and/or nf- kappa b activity and use thereof
JP2010508358A (ja) 2006-11-01 2010-03-18 ブリストル−マイヤーズ スクイブ カンパニー グルココルチコイド受容体、ＡＰ−１、および／またはＮＦ−κＢ活性の調節剤、並びにその使用
ES2393885T7 (es) 2007-06-04 2014-01-30 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7828840B2 (en) 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
WO2009158380A1 (en) 2008-06-24 2009-12-30 Bristol-Myers Squibb Company Cyclopentathiophene modulators of the glucocorticoid receptor, ap-1, and/or nf-kappa b activity and use thereof
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
US10011637B2 (en) 2013-06-05 2018-07-03 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2015027021A1 (en) 2013-08-22 2015-02-26 Bristol-Myers Squibb Company Imide and acylurea derivatives as modulators of the glucocorticoid receptor
CN113292495B (zh) * 2021-06-18 2022-09-13 迪嘉药业集团有限公司 一种 (s)-氨基化合物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3395150A (en) * 1965-02-26 1968-07-30 Squibb & Sons Inc Benzothiazepine carboxamides and derivatives thereof
GB1305278A (nl) * 1970-03-12 1973-01-31

Also Published As

Publication number Publication date
NO161558C (no) 1989-08-30
DK157881C (da) 1990-07-23
IL66501A (en) 1987-10-20
NL930112I2 (nl) 1996-11-01
ES514856A0 (es) 1985-02-01
AU8701482A (en) 1983-05-12
AR240806A1 (es) 1991-02-28
AR240806A2 (es) 1991-02-28
AR240807A2 (es) 1991-02-28
NL930112I1 (nl) 1993-10-18
ES526887A0 (es) 1986-04-16
AR241222A1 (es) 1992-02-28
AR240807A1 (es) 1991-02-28
NO161558B (no) 1989-05-22
KR890003425B1 (ko) 1989-09-20
PT75395B (en) 1985-11-15
ES8504728A1 (es) 1985-04-16
DE3269625D1 (en) 1986-04-10
KR900001191B1 (ko) 1990-02-28
CA1196636A (en) 1985-11-12
IE53668B1 (en) 1989-01-04
ES526886A0 (es) 1985-11-01
IE821929L (en) 1983-02-11
KR900001190B1 (ko) 1990-02-28
DK157881B (da) 1990-02-26
ES8604523A1 (es) 1986-02-01
FI822770L (fi) 1983-02-12
ES8602682A1 (es) 1985-12-01
IL66501A0 (en) 1982-12-31
ES526889A0 (es) 1986-02-01
EP0072352A1 (de) 1983-02-16
DK358682A (da) 1983-02-12
ATE18397T1 (de) 1986-03-15
FI822770A0 (fi) 1982-08-09
GR77256B (nl) 1984-09-11
ES530658A0 (es) 1985-12-01
NO822722L (no) 1983-02-14
FI76074B (fi) 1988-05-31
KR840001139A (ko) 1984-03-28
DD202546A5 (de) 1983-09-21
EP0072352B1 (de) 1986-03-05
ES8601142A1 (es) 1985-11-01
FI76074C (fi) 1988-09-09
HK93387A (en) 1987-12-18
AU561395B2 (en) 1987-05-07
GB2103614A (en) 1983-02-23
ES526888A0 (es) 1985-04-16
HU189628B (en) 1986-07-28
ES8606285A1 (es) 1986-04-16
NZ201555A (en) 1986-06-11
PT75395A (en) 1982-09-01
GB2103614B (en) 1984-11-21
ES8502974A1 (es) 1985-02-01

Similar Documents

Publication Publication Date Title
GB2103614B (en) Benzazepin-2-ones
ZA821128B (en) Imidazodiazepines
GB2111579B (en) Stud-fastener
JPS57204474A (en) Logic-analyzer
CS775282A2 (en) Zpusob vyroby novych ergolinovych derivatu
GB2108362B (en) Numnah
DE3262585D1 (en) Roll-blind
ZA812706B (en) Gas-scrubber
CS494682A2 (en) Zpusob vyroby granuli mocoviny
BG48180A1 (en) Stereocomparator
GB2105123B (en) Fuseholders
MY8600265A (en) Fuseholders
GB8416656D0 (en) Thioanthraquinones
ZA82475B (en) Mouldboards
GB2111489B (en) N-isopropyl-noratropine-n-oxide
CA47741S (en) Walking-board
CA48729S (en) Infiltrometer
CS51583A2 (en) Zpusob vyroby heterocyklickych derivatu guanidinu
BG41674A1 (en) Stabilograph
CS329781A2 (en) Rotacni tridici stroj
CS435581A1 (en) Merici zarizeni
BG35558A1 (en) Devider- separator
CS55581A1 (en) Zdokonalovac tvorby palivovej zmesi spalovacich motorov
YU60581A (en) Dynamo-circuit
BG49621A1 (en) Press- collector