CY1124052T1 - Δισκιο διασπειρομενο στο στομα περιεχον οιστετρολη - Google Patents
Δισκιο διασπειρομενο στο στομα περιεχον οιστετροληInfo
- Publication number
- CY1124052T1 CY1124052T1 CY20211100348T CY211100348T CY1124052T1 CY 1124052 T1 CY1124052 T1 CY 1124052T1 CY 20211100348 T CY20211100348 T CY 20211100348T CY 211100348 T CY211100348 T CY 211100348T CY 1124052 T1 CY1124052 T1 CY 1124052T1
- Authority
- CY
- Cyprus
- Prior art keywords
- particles
- dosage unit
- estetrol
- weight
- loaded particles
- Prior art date
Links
- AJIPIJNNOJSSQC-NYLIRDPKSA-N estetrol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)[C@@H]4O)O)[C@@H]4[C@@H]3CCC2=C1 AJIPIJNNOJSSQC-NYLIRDPKSA-N 0.000 title abstract 5
- 229950009589 estetrol Drugs 0.000 title abstract 4
- 239000007919 dispersible tablet Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 7
- 239000007788 liquid Substances 0.000 abstract 4
- 239000007787 solid Substances 0.000 abstract 4
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15172755 | 2015-06-18 | ||
| PCT/EP2016/064181 WO2016203044A1 (en) | 2015-06-18 | 2016-06-20 | Orodispersible tablet containing estetrol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1124052T1 true CY1124052T1 (el) | 2022-05-27 |
Family
ID=53476702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20211100348T CY1124052T1 (el) | 2015-06-18 | 2021-04-21 | Δισκιο διασπειρομενο στο στομα περιεχον οιστετρολη |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10888518B2 (enExample) |
| EP (1) | EP3310346B1 (enExample) |
| JP (1) | JP6813150B2 (enExample) |
| CN (1) | CN107750157B (enExample) |
| CA (1) | CA2988362C (enExample) |
| CY (1) | CY1124052T1 (enExample) |
| DK (1) | DK3310346T3 (enExample) |
| ES (1) | ES2877476T3 (enExample) |
| HR (1) | HRP20210555T1 (enExample) |
| HU (1) | HUE054551T2 (enExample) |
| LT (1) | LT3310346T (enExample) |
| MA (1) | MA44206B1 (enExample) |
| MD (1) | MD3310346T2 (enExample) |
| PL (1) | PL3310346T3 (enExample) |
| PT (1) | PT3310346T (enExample) |
| RS (1) | RS61777B1 (enExample) |
| SI (1) | SI3310346T1 (enExample) |
| SM (1) | SMT202100350T1 (enExample) |
| WO (1) | WO2016203044A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107266514A (zh) | 2011-06-01 | 2017-10-20 | 埃斯特拉私人有限责任公司 | 用于产生雌四醇中间体的方法 |
| SI2714712T1 (sl) | 2011-06-01 | 2016-11-30 | Estetra S.P.R.L. | Postopek za proizvodnjo intermediatov estetrola |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| US10894014B2 (en) | 2015-06-18 | 2021-01-19 | Estetra Sprl | Orodispersible tablet containing Estetrol |
| JP6863547B2 (ja) | 2015-06-18 | 2021-04-21 | エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ | エステトロール成分を含有する口腔内崩壊性投与単位 |
| GEP20217243B (en) | 2015-06-18 | 2021-04-26 | Sprl Estetra | Orodispersible dosage unit containing an estetrol component |
| US10888518B2 (en) | 2015-06-18 | 2021-01-12 | Estetra Sprl | Orodispersible tablet containing estetrol |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
| EP3647413A1 (en) * | 2018-10-31 | 2020-05-06 | Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas O.A., M.P. (CIEMAT) | Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation |
| HU231240B1 (hu) | 2019-09-03 | 2022-04-28 | Richter Gedeon Nyrt. | Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására |
| ES2915058B2 (es) * | 2019-09-27 | 2024-06-21 | Ind Chimica Srl | Proceso para preparar (15alfa,16alfa,17beta)-estra-1,3,5(10)-trieno-3,15,16,17-tetrol (Estetrol) e intermedios de dicho proceso |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
| JP2023543953A (ja) | 2020-09-29 | 2023-10-18 | ミリセント・ファーマ・リミテッド | 口腔内分散性配合物 |
| EP4243602A4 (en) | 2020-11-16 | 2024-11-13 | Orcosa Inc. | Improved use of cannabinoids in the treatment of alzheimer's disease |
| US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
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| WO2016023009A1 (en) | 2014-08-07 | 2016-02-11 | Wake Forest University Health Sciences | Compositions and methods for clearing a biological sample |
| US9962395B2 (en) | 2014-09-29 | 2018-05-08 | The Regents Of The University Of California | Compositions and methods for maintaining cognitive function |
| WO2016187269A1 (en) | 2015-05-18 | 2016-11-24 | Agile Therapeutics, Inc. | Contraceptive compositions and methods for improved efficacy and modulation of side effects |
| GEP20217243B (en) | 2015-06-18 | 2021-04-26 | Sprl Estetra | Orodispersible dosage unit containing an estetrol component |
| JP6863547B2 (ja) | 2015-06-18 | 2021-04-21 | エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ | エステトロール成分を含有する口腔内崩壊性投与単位 |
| US10894014B2 (en) | 2015-06-18 | 2021-01-19 | Estetra Sprl | Orodispersible tablet containing Estetrol |
| US10888518B2 (en) | 2015-06-18 | 2021-01-12 | Estetra Sprl | Orodispersible tablet containing estetrol |
| CN113750108B (zh) | 2015-06-23 | 2025-08-19 | 莱昂实验室制药股份有限公司 | 用于过重女性患者的基于屈螺酮的避孕药 |
| CA3178291A1 (en) | 2016-08-05 | 2018-04-12 | Estetra Srl | Method for the management of dysmenorrhea and menstrual pain |
| US20200046729A1 (en) | 2016-08-05 | 2020-02-13 | Estetra Sprl | Methods using combined oral contraceptive compositions with reduced cardiovascular effects |
| EP4140489A1 (en) | 2018-02-07 | 2023-03-01 | Estetra SRL | Contraceptive composition with reduced cardiovascular effects |
-
2016
- 2016-06-20 US US15/737,189 patent/US10888518B2/en active Active
- 2016-06-20 PT PT167333525T patent/PT3310346T/pt unknown
- 2016-06-20 HU HUE16733352A patent/HUE054551T2/hu unknown
- 2016-06-20 ES ES16733352T patent/ES2877476T3/es active Active
- 2016-06-20 SI SI201631150T patent/SI3310346T1/sl unknown
- 2016-06-20 HR HRP20210555TT patent/HRP20210555T1/hr unknown
- 2016-06-20 SM SM20210350T patent/SMT202100350T1/it unknown
- 2016-06-20 MA MA44206A patent/MA44206B1/fr unknown
- 2016-06-20 LT LTEP16733352.5T patent/LT3310346T/lt unknown
- 2016-06-20 CN CN201680035672.3A patent/CN107750157B/zh active Active
- 2016-06-20 JP JP2017563337A patent/JP6813150B2/ja active Active
- 2016-06-20 MD MDE20180408T patent/MD3310346T2/ro unknown
- 2016-06-20 RS RS20210486A patent/RS61777B1/sr unknown
- 2016-06-20 PL PL16733352T patent/PL3310346T3/pl unknown
- 2016-06-20 EP EP16733352.5A patent/EP3310346B1/en active Active
- 2016-06-20 WO PCT/EP2016/064181 patent/WO2016203044A1/en not_active Ceased
- 2016-06-20 DK DK16733352.5T patent/DK3310346T3/da active
- 2016-06-20 CA CA2988362A patent/CA2988362C/en active Active
-
2021
- 2021-04-21 CY CY20211100348T patent/CY1124052T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2877476T3 (es) | 2021-11-16 |
| CN107750157A (zh) | 2018-03-02 |
| JP2018517715A (ja) | 2018-07-05 |
| CA2988362A1 (en) | 2016-12-22 |
| PT3310346T (pt) | 2021-04-22 |
| CN107750157B (zh) | 2021-07-13 |
| EP3310346A1 (en) | 2018-04-25 |
| HRP20210555T1 (hr) | 2021-05-14 |
| MA44206A (fr) | 2018-04-25 |
| WO2016203044A1 (en) | 2016-12-22 |
| MD3310346T2 (ro) | 2021-06-30 |
| DK3310346T3 (da) | 2021-05-25 |
| PL3310346T3 (pl) | 2021-10-25 |
| CA2988362C (en) | 2022-07-19 |
| US10888518B2 (en) | 2021-01-12 |
| EP3310346B1 (en) | 2021-03-24 |
| SI3310346T1 (sl) | 2021-07-30 |
| SMT202100350T1 (it) | 2021-07-12 |
| RS61777B1 (sr) | 2021-06-30 |
| HK1254649A1 (en) | 2019-07-26 |
| MA44206B1 (fr) | 2021-04-30 |
| HUE054551T2 (hu) | 2021-09-28 |
| JP6813150B2 (ja) | 2021-01-13 |
| US20180153801A1 (en) | 2018-06-07 |
| LT3310346T (lt) | 2021-06-10 |
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