CY1121383T1 - Μεθοδος κατευθυνομενης διαφοροποιησης που παραγει κερατοειδικα ενδοθηλιακα κυτταρα - Google Patents

Μεθοδος κατευθυνομενης διαφοροποιησης που παραγει κερατοειδικα ενδοθηλιακα κυτταρα

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Publication number
CY1121383T1
CY1121383T1 CY20191100314T CY191100314T CY1121383T1 CY 1121383 T1 CY1121383 T1 CY 1121383T1 CY 20191100314 T CY20191100314 T CY 20191100314T CY 191100314 T CY191100314 T CY 191100314T CY 1121383 T1 CY1121383 T1 CY 1121383T1
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Cyprus
Prior art keywords
cells
directed
entothy
differentialization
corned
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CY20191100314T
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English (en)
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Kathryn L. Mccabe
Shi-Jiang Lu
Robert Lanza
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Astellas Institute For Regenerative Medicine
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Publication of CY1121383T1 publication Critical patent/CY1121383T1/el

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Abstract

Η αποκάλυψη αυτή γενικώς αφορά σε κυτταροβασιζόμενες θεραπείες για θεραπεία οπτικών διαταραχών, συμπεριλαμβανομένων διαταραχών του κερατοειδούς. Μέθοδοι δίδονται παραδειγματικά για κατευθυνόμενη διαφοροποίηση κερατοειδικών κυττάρων από βλαστοκύτταρα. Επίσης παρέχονται συνθέσεις κερατοειδικών ενδοθηλιακών κυττάρων και χρήσεις αυτών. Παραδειγματικές συνθέσεις δεικνύουν βελτιωμένη πυκνότητα κυττάρου ή/και περισσότερο «νεανικού» γονιδίου έκφραση σε σχέση προς κύτταρα που λαμβάνονται από δωρηθέντα ιστό.
CY20191100314T 2011-12-06 2019-03-15 Μεθοδος κατευθυνομενης διαφοροποιησης που παραγει κερατοειδικα ενδοθηλιακα κυτταρα CY1121383T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161567479P 2011-12-06 2011-12-06
PCT/US2012/068305 WO2013086236A2 (en) 2011-12-06 2012-12-06 Method of directed differentiation producing corneal endothelial cells, compositions thereof, and uses thereof

Publications (1)

Publication Number Publication Date
CY1121383T1 true CY1121383T1 (el) 2020-05-29

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CY20191100314T CY1121383T1 (el) 2011-12-06 2019-03-15 Μεθοδος κατευθυνομενης διαφοροποιησης που παραγει κερατοειδικα ενδοθηλιακα κυτταρα

Country Status (15)

Country Link
US (2) US9752118B2 (el)
EP (2) EP2788472B1 (el)
CA (2) CA3178138A1 (el)
CY (1) CY1121383T1 (el)
DK (1) DK2788472T3 (el)
ES (1) ES2716200T3 (el)
HR (1) HRP20190460T1 (el)
HU (1) HUE041929T2 (el)
LT (1) LT2788472T (el)
PL (1) PL2788472T3 (el)
PT (1) PT2788472T (el)
RS (1) RS58526B1 (el)
SI (1) SI2788472T1 (el)
TR (1) TR201903889T4 (el)
WO (1) WO2013086236A2 (el)

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JP6770435B2 (ja) 2014-10-31 2020-10-14 京都府公立大学法人 ラミニンによる網膜および神経の新規治療
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KR102619458B1 (ko) * 2017-06-16 2023-12-29 학교법인 도시샤 mTOR 인히비터를 포함하는, 눈의 증상, 장해 또는 질환을 치료 또는 예방하기 위한 의약 및 그 응용
CN107475200B (zh) * 2017-08-08 2020-12-22 浙江大学 一种背根神经节源的神经嵴干细胞的分离、培养与分化方法
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KR102114787B1 (ko) * 2018-04-02 2020-05-26 중앙대학교 산학협력단 리보핵산분해효소 5 고발현된 각막 내피세포를 포함하는 3차원 각막 내피 이식체 제조방법
JP7474520B2 (ja) * 2019-04-05 2024-04-25 ザ・ユニバーシティ・オブ・ホンコン 哺乳類の拡大ポテンシャル幹細胞のための培地、その組成物および方法
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