SG11201701693RA - Corneal endothelial cell marker - Google Patents

Corneal endothelial cell marker

Info

Publication number
SG11201701693RA
SG11201701693RA SG11201701693RA SG11201701693RA SG11201701693RA SG 11201701693R A SG11201701693R A SG 11201701693RA SG 11201701693R A SG11201701693R A SG 11201701693RA SG 11201701693R A SG11201701693R A SG 11201701693RA SG 11201701693R A SG11201701693R A SG 11201701693RA
Authority
SG
Singapore
Prior art keywords
endothelial cell
cell marker
corneal endothelial
corneal
marker
Prior art date
Application number
SG11201701693RA
Inventor
Kohji Nishida
Motokazu Tsujikawa
Susumu Hara
Satoshi Kawasaki
Masahito Yoshihara
Masayoshi Itoh
Hideya Kawaji
Hiroko Ohmiya
Original Assignee
Univ Osaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka filed Critical Univ Osaka
Publication of SG11201701693RA publication Critical patent/SG11201701693RA/en

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0621Eye cells, e.g. cornea, iris pigmented cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
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SG11201701693RA 2014-09-05 2015-09-04 Corneal endothelial cell marker SG11201701693RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014180985 2014-09-05
PCT/JP2015/075164 WO2016035874A1 (en) 2014-09-05 2015-09-04 Corneal endothelial cell marker

Publications (1)

Publication Number Publication Date
SG11201701693RA true SG11201701693RA (en) 2017-04-27

Family

ID=55439929

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201701693RA SG11201701693RA (en) 2014-09-05 2015-09-04 Corneal endothelial cell marker

Country Status (8)

Country Link
US (1) US10968428B2 (en)
EP (1) EP3190181B1 (en)
JP (1) JP6226349B2 (en)
KR (1) KR101945134B1 (en)
CN (1) CN107075485B (en)
ES (1) ES2807625T3 (en)
SG (1) SG11201701693RA (en)
WO (1) WO2016035874A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016093359A1 (en) * 2014-12-11 2016-06-16 学校法人慶應義塾 Method for producing therapeutic corneal endothelial substitute cell sphere
EP3628056A4 (en) * 2017-04-28 2021-03-03 Avellino Lab USA, Inc. Methods for detecting alleles associated with keratoconus
JP6758631B2 (en) 2017-06-19 2020-09-23 国立大学法人大阪大学 Corneal endothelial cell marker and its use
WO2020213969A2 (en) * 2019-04-17 2020-10-22 연세대학교 산학협력단 Biomarker for diagnosing corneal endothelial cell dysfunction
CN112430672B (en) * 2020-12-08 2023-10-27 江苏艾尔康生物医药科技有限公司 Identification method of human corneal endothelial cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1835023A4 (en) 2004-12-09 2008-09-10 Amano Shiro Human corneal endothelial cell-derived precursor cell and cell aggregate, process for producing the same, and method for transplanting precursor cell and cell aggregate
EP2532738B1 (en) 2010-02-05 2016-12-21 Cornea Regeneration Institute Co., Ltd. Method for culture of corneal endothelial cells, process for production of corneal endothelial cell sheet for transplantation purposes, and culture kit for corneal endothelial cells
WO2013012087A1 (en) * 2011-07-15 2013-01-24 国立大学法人大阪大学 Method for preparing corneal endothelial cell
US9347042B2 (en) 2011-10-06 2016-05-24 Keio University Method for producing corneal endothelial cell
WO2014007402A1 (en) * 2012-07-06 2014-01-09 京都府公立大学法人 Differentiation marker for and differentiation control for ocular cells
SG11201500386WA (en) * 2012-07-18 2015-04-29 Singapore Health Serv Pte Ltd Cell culture of corneal endothelial cells
EP3029140A4 (en) * 2013-07-30 2017-06-28 Kyoto Prefectural Public University Corporation Corneal endothelial cell marker

Also Published As

Publication number Publication date
US20170253855A1 (en) 2017-09-07
CN107075485A (en) 2017-08-18
KR20170042784A (en) 2017-04-19
ES2807625T3 (en) 2021-02-23
WO2016035874A1 (en) 2016-03-10
JPWO2016035874A1 (en) 2017-08-10
EP3190181A1 (en) 2017-07-12
JP6226349B2 (en) 2017-11-08
EP3190181A4 (en) 2018-03-07
US10968428B2 (en) 2021-04-06
KR101945134B1 (en) 2019-02-01
CN107075485B (en) 2021-10-01
EP3190181B1 (en) 2020-06-17

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