CY1120593T1 - Διαμορφωτες του ρυθμιστη αγωγιμοτητας διαμεμβρανης κυστικης ινωσης - Google Patents

Διαμορφωτες του ρυθμιστη αγωγιμοτητας διαμεμβρανης κυστικης ινωσης

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Publication number
CY1120593T1
CY1120593T1 CY181100855T CY181100855T CY1120593T1 CY 1120593 T1 CY1120593 T1 CY 1120593T1 CY 181100855 T CY181100855 T CY 181100855T CY 181100855 T CY181100855 T CY 181100855T CY 1120593 T1 CY1120593 T1 CY 1120593T1
Authority
CY
Cyprus
Prior art keywords
fibria
cystic
membrane conductivity
conductivity modifiers
modifiers
Prior art date
Application number
CY181100855T
Other languages
Greek (el)
English (en)
Inventor
Xiaoqing Yang
Ruah Sara S Hadida
Peter D J Grootenhuis
Goor Fredrick F Van
Martyn C Botfield
Gregor Zlokarnik
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of CY1120593T1 publication Critical patent/CY1120593T1/el

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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
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CY181100855T 2009-03-20 2018-08-13 Διαμορφωτες του ρυθμιστη αγωγιμοτητας διαμεμβρανης κυστικης ινωσης CY1120593T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16213009P 2009-03-20 2009-03-20
PCT/US2010/028062 WO2010108155A1 (en) 2009-03-20 2010-03-19 Modulators of cystic fibrosis transmembrane conductance regulator

Publications (1)

Publication Number Publication Date
CY1120593T1 true CY1120593T1 (el) 2019-12-11

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US (4) US8614325B2 (enExample)
EP (1) EP2408749B1 (enExample)
JP (3) JP5636418B2 (enExample)
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