PT2408749T - Moduladores do regulador da condutância transmembranar da fibrose cística - Google Patents

Moduladores do regulador da condutância transmembranar da fibrose cística

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Publication number
PT2408749T
PT2408749T PT10710748T PT10710748T PT2408749T PT 2408749 T PT2408749 T PT 2408749T PT 10710748 T PT10710748 T PT 10710748T PT 10710748 T PT10710748 T PT 10710748T PT 2408749 T PT2408749 T PT 2408749T
Authority
PT
Portugal
Prior art keywords
modulators
cystic fibrosis
fibrosis transmembrane
conductance regulator
transmembrane conductance
Prior art date
Application number
PT10710748T
Other languages
English (en)
Portuguese (pt)
Inventor
d j grootenhuis Peter
Yang Xiaoqing
S Hadida Ruah Sara
F Van Goor Fredrick
C Botfield Martyn
Zlokarnik Gregor
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of PT2408749T publication Critical patent/PT2408749T/pt

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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
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    • C—CHEMISTRY; METALLURGY
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    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
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PT10710748T 2009-03-20 2010-03-19 Moduladores do regulador da condutância transmembranar da fibrose cística PT2408749T (pt)

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