CY1118951T1 - Χρηση αντισωματων υποδοχεα ιντερλευκινης-4 και συνθεσεις αυτων - Google Patents

Χρηση αντισωματων υποδοχεα ιντερλευκινης-4 και συνθεσεις αυτων

Info

Publication number
CY1118951T1
CY1118951T1 CY20171100233T CY171100233T CY1118951T1 CY 1118951 T1 CY1118951 T1 CY 1118951T1 CY 20171100233 T CY20171100233 T CY 20171100233T CY 171100233 T CY171100233 T CY 171100233T CY 1118951 T1 CY1118951 T1 CY 1118951T1
Authority
CY
Cyprus
Prior art keywords
interleukin
compositions
receptor antibodies
antibodies
receptor
Prior art date
Application number
CY20171100233T
Other languages
English (en)
Inventor
Arvia E Morris
John D Pluenneke
Richard J Armitage
Jose Carlos Escobar
Original Assignee
Immunex Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27504940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1118951(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/785,934 external-priority patent/US20020002132A1/en
Application filed by Immunex Corporation filed Critical Immunex Corporation
Publication of CY1118951T1 publication Critical patent/CY1118951T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει ένα αντίσωμα που ανταγωνίζεται για δέσμευση με ένα αντίσωμα αναφοράς στον υποδοχέα της ανθρώπινης IL-4 (IL-4R), όπου η ελαφρά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID NO: 10 και η βαριά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID NO: 12, ή η ελαφρά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID NO: 14 και η βαριά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID NO: 16 ή η ελαφρά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID NO: 18 και η βαριά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID ΝΟ:20 ή η ελαφρά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID ΝΟ:22 και η βαριά αλυσίδα του αντισώματος αναφοράς περιέχει την αλληλουχία SEQ ID ΝΟ:24 και χρήσεις αυτού.
CY20171100233T 2000-05-26 2017-02-21 Χρηση αντισωματων υποδοχεα ιντερλευκινης-4 και συνθεσεις αυτων CY1118951T1 (el)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US57980800A 2000-05-26 2000-05-26
US66534300A 2000-09-19 2000-09-19
US09/785,934 US20020002132A1 (en) 2000-05-26 2001-02-15 Use of interleukin-4 antagonists and compositions thereof
US84781601A 2001-05-01 2001-05-01
EP10185626.8A EP2292665B1 (en) 2000-05-26 2001-05-25 Use of interleukin-4 antibodies and compositions thereof
EP01952133A EP1283851B1 (en) 2000-05-26 2001-05-25 Use of il-4r antibodies and compositions thereof

Publications (1)

Publication Number Publication Date
CY1118951T1 true CY1118951T1 (el) 2018-01-10

Family

ID=27504940

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20171100233T CY1118951T1 (el) 2000-05-26 2017-02-21 Χρηση αντισωματων υποδοχεα ιντερλευκινης-4 και συνθεσεις αυτων

Country Status (12)

Country Link
US (8) US7186809B2 (el)
EP (4) EP2990420B1 (el)
AT (1) ATE551363T1 (el)
AU (1) AU2001272925A1 (el)
CA (1) CA2409267C (el)
CY (1) CY1118951T1 (el)
DE (1) DE16192152T1 (el)
DK (1) DK2990420T3 (el)
ES (3) ES2382891T3 (el)
MX (1) MXPA02011682A (el)
PT (1) PT2990420T (el)
WO (1) WO2001092340A2 (el)

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