DE60229509D1 - Anti-osteopontin-antikörper und dessen verwendung - Google Patents

Anti-osteopontin-antikörper und dessen verwendung

Info

Publication number
DE60229509D1
DE60229509D1 DE60229509T DE60229509T DE60229509D1 DE 60229509 D1 DE60229509 D1 DE 60229509D1 DE 60229509 T DE60229509 T DE 60229509T DE 60229509 T DE60229509 T DE 60229509T DE 60229509 D1 DE60229509 D1 DE 60229509D1
Authority
DE
Germany
Prior art keywords
osteopontin antibody
osteopontin
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60229509T
Other languages
English (en)
Inventor
Toshimitsu Uede
Shigeyuki Kon
Yukihiko Saeki
Yasuyuki Yokosaki
Masaki Noda
Nobuchika Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Immuno Biological Laboratories Co Ltd
Original Assignee
Astellas Pharma Inc
Immuno Biological Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc, Immuno Biological Laboratories Co Ltd filed Critical Astellas Pharma Inc
Application granted granted Critical
Publication of DE60229509D1 publication Critical patent/DE60229509D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60229509T 2001-04-05 2002-04-04 Anti-osteopontin-antikörper und dessen verwendung Expired - Lifetime DE60229509D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001107578 2001-04-05
JP2001290700 2001-09-25
PCT/JP2002/003382 WO2002081522A1 (fr) 2001-04-05 2002-04-04 Anticorps dirigé contre l'ostéopontine, et son utilisation

Publications (1)

Publication Number Publication Date
DE60229509D1 true DE60229509D1 (de) 2008-12-04

Family

ID=26613159

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60229509T Expired - Lifetime DE60229509D1 (de) 2001-04-05 2002-04-04 Anti-osteopontin-antikörper und dessen verwendung

Country Status (20)

Country Link
US (2) US20040234524A1 (de)
EP (2) EP1754719A3 (de)
JP (1) JP4230776B2 (de)
KR (1) KR100881900B1 (de)
CN (1) CN100469793C (de)
AR (1) AR033121A1 (de)
AT (1) ATE412013T1 (de)
AU (1) AU2002244968B2 (de)
BR (1) BR0208809A (de)
CA (1) CA2443330A1 (de)
CZ (1) CZ20032697A3 (de)
DE (1) DE60229509D1 (de)
ES (1) ES2314040T3 (de)
HU (1) HUP0401561A2 (de)
MX (1) MXPA03009052A (de)
NO (1) NO20034405L (de)
NZ (1) NZ528483A (de)
PL (1) PL366469A1 (de)
RU (1) RU2299888C2 (de)
WO (1) WO2002081522A1 (de)

Families Citing this family (32)

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JP2004532633A (ja) * 2001-05-09 2004-10-28 ビオ・ビジョン・アーゲー 進行性の慢性痴呆疾患の検出方法、これに適したペプチド及び検出試薬
KR101008758B1 (ko) 2001-09-18 2011-01-14 제넨테크, 인크. 종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
EP1431310A4 (de) * 2001-09-25 2005-03-23 Immuno Biological Lab Co Ltd Rekombinanter anti-osteopontin-antikörper und dessen verwendung
US7678889B2 (en) * 2002-08-06 2010-03-16 Diadexus, Inc. Compositions and methods relating to ovarian specific genes and proteins
WO2004103403A1 (ja) * 2003-05-23 2004-12-02 Immuno-Biological Laboratories Co., Ltd. 免疫担当細胞活性化阻害剤およびその用途
WO2005020785A2 (en) * 2003-07-15 2005-03-10 The Regents Of The University Of California Discovery of the microorganism that causes the human autoimmune disease, primary biliary cirrhosis
AU2004324192A1 (en) * 2004-10-13 2006-04-27 Genentech, Inc. Method for treating tumors using anti-osteopontin antibodies
JP4871740B2 (ja) 2005-01-13 2012-02-08 株式会社ジーンテクノサイエンス 抗α９インテグリン抗体とその用途
CA2653661A1 (en) * 2006-05-31 2007-12-06 Astellas Pharma Inc. Humanized anti-human osteopontin antibody
DK2047863T3 (da) 2006-06-08 2013-09-16 Chugai Pharmaceutical Co Ltd Middel til forebyggelse eller behandling af inflammatoriske sygdomme
WO2007149948A2 (en) * 2006-06-20 2007-12-27 The Gov. Of The Usa As Represented By The Secretary Of The Department Of Health And Human Services Compositions and methods for diagnosis and treatment of tumors
KR101429783B1 (ko) 2006-07-12 2014-08-18 가부시키가이샤 진 테크노 사이언스 항 인간 α９ 인테그린 항체와 그 용도
EP2077325A4 (de) * 2006-09-11 2012-04-11 Immuno Biological Lab Co Ltd Monoklonaler antikörper und dessen verwendung
DK2075258T3 (da) 2006-10-26 2012-09-17 Gene Techno Science Co Ltd Antistof mod RGD i en aminosyresekvens i et ekstracellulært matrixprotein samt fremgangsmåde til dets fremstilling og dets anvendelse
CN101293916A (zh) * 2007-04-24 2008-10-29 上海国健生物技术研究院 骨桥蛋白的功能表位、与其特异性结合的单克隆抗体及用途
CN101293924A (zh) * 2007-04-24 2008-10-29 上海国健生物技术研究院 骨桥蛋白的功能表位、与其特异性结合的单克隆抗体及其在制备抗肿瘤转移药物中的用途
KR100894265B1 (ko) * 2007-06-05 2009-04-21 재단법인서울대학교산학협력재단 골형성 촉진 펩타이드를 함유하는 주입형 골재생재
EP2201383B1 (de) 2007-10-10 2014-01-15 Roche Diagnostics GmbH Mittel und verfahren zur überwachung eines myokardinfarkts und dessen behandlung
EP2236604B1 (de) 2007-12-05 2016-07-06 Chugai Seiyaku Kabushiki Kaisha Anti-nr10-antikörper und verwendung davon
JP2011509650A (ja) 2008-01-11 2011-03-31 株式会社ジーンテクノサイエンス ヒト化抗−α９インテグリン抗体及びその使用
CN101918549B (zh) 2008-01-11 2012-11-28 财团法人化学及血清疗法研究所 改良的人源化的抗-人α9-整联蛋白抗体
CA2721716C (en) 2008-04-24 2019-09-24 Gene Techno Science Co., Ltd. Humanized antibodies specific for amino acid sequence rgd of an extracellular matrix protein and the uses thereof
EP2399937B1 (de) 2009-02-23 2016-04-27 Gene Techno Science Co., Ltd. Antikörper gegen humanes alpha9-integrin und dessen verwendung
EP2406285B1 (de) 2009-03-10 2016-03-09 Gene Techno Science Co., Ltd. Erzeugung, expression und charakterisierung des humanisierten monoklonalen antikörpers k33n
EP2431738A4 (de) * 2009-05-12 2013-05-22 Innopharmascreen Inc Screening-verfahren für osteopontin-inhibitor und damit hergestellter inhibitor
US8617829B2 (en) 2009-09-24 2013-12-31 Gene Techno Science Co., Ltd. Humanized antibodies specific for amino acid sequence RGD of an extracellular matrix protein and the uses thereof
WO2012117067A1 (en) 2011-03-01 2012-09-07 Novo Nordisk A/S Antagonistic dr3 ligands
GB2493540A (en) * 2011-08-10 2013-02-13 Follicum Ab Agents for stimulating hair growth in mammals
TW201623329A (zh) 2014-06-30 2016-07-01 亞佛瑞司股份有限公司 針對骨調素截斷變異體的疫苗及單株抗體暨其用途
CA2980992C (en) 2015-04-14 2024-01-23 Akihisa Kaneko Pharmaceutical composition for prevention and/or treatment of atopic dermatitis containing il-31 antagonist as active ingredient
WO2021030209A1 (en) * 2019-08-09 2021-02-18 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic antibodies against osteopontin
BR112022006590A2 (pt) 2019-11-20 2022-06-28 Chugai Pharmaceutical Co Ltd Preparação contendo anticorpos

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
US63241A (en) * 1867-03-26 Jacob green
US63247A (en) * 1867-03-26 hbtdeick
US171358A (en) * 1875-12-21 Improvement in machines for trimming and punching roofing-slates
US705842A (en) * 1901-10-25 1902-07-29 Daniel M Moroney Machine for assembling links in making chain belts.
US5459060A (en) * 1989-08-24 1995-10-17 Bioclonetics Incorporated Human monoclonal antibodies directed against the transmembrane glycoprotein (gp41) of human immunodeficiency virus-1 (HIV-1)
GB9122820D0 (en) * 1991-10-28 1991-12-11 Wellcome Found Stabilised antibodies
US6114143A (en) * 1993-03-11 2000-09-05 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Anti-HIV monoclonal antibody
EP0705842A2 (de) * 1994-10-06 1996-04-10 Hoechst Aktiengesellschaft Über Stimulation von Chondrozyten mit 1L-1Beta regulierte Genen
US6414219B1 (en) * 1998-06-30 2002-07-02 Rutgers, The State University Of New Jersey Osteopontin knock-out mouse and methods of use thereof
CA2370301A1 (en) * 1999-04-15 2000-10-26 Children's Medical Center Corporation Osteopontin-derived chemotactic and inhibitory agents and uses therefor
DE60131525T2 (de) * 2000-03-23 2008-09-25 Glaxo Group Ltd., Greenford Verfahren zum screening von inhibitoren für osteopontin
EP1431310A4 (de) * 2001-09-25 2005-03-23 Immuno Biological Lab Co Ltd Rekombinanter anti-osteopontin-antikörper und dessen verwendung

Also Published As

Publication number Publication date
EP1375518A4 (de) 2004-12-08
AR033121A1 (es) 2003-12-03
AU2002244968B2 (en) 2007-07-26
JP4230776B2 (ja) 2009-02-25
RU2299888C2 (ru) 2007-05-27
CA2443330A1 (en) 2002-10-17
NO20034405D0 (no) 2003-10-02
HUP0401561A2 (hu) 2004-11-29
EP1754719A3 (de) 2007-05-16
CN1513000A (zh) 2004-07-14
NZ528483A (en) 2008-03-28
EP1375518B1 (de) 2008-10-22
PL366469A1 (en) 2005-02-07
MXPA03009052A (es) 2004-10-15
EP1375518A1 (de) 2004-01-02
US20080069815A1 (en) 2008-03-20
US20040234524A1 (en) 2004-11-25
JPWO2002081522A1 (ja) 2004-07-29
CZ20032697A3 (cs) 2004-01-14
CN100469793C (zh) 2009-03-18
ATE412013T1 (de) 2008-11-15
KR100881900B1 (ko) 2009-02-04
WO2002081522A1 (fr) 2002-10-17
RU2003132446A (ru) 2005-04-27
BR0208809A (pt) 2004-03-09
ES2314040T3 (es) 2009-03-16
NO20034405L (no) 2003-12-05
EP1754719A2 (de) 2007-02-21
KR20030092022A (ko) 2003-12-03

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