CY1116027T1 - Παραγωγα πυριδινης και πυριμιδινης ως mglur2 ανταγωνιστες - Google Patents

Παραγωγα πυριδινης και πυριμιδινης ως mglur2 ανταγωνιστες

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Publication number
CY1116027T1
CY1116027T1 CY20151100147T CY151100147T CY1116027T1 CY 1116027 T1 CY1116027 T1 CY 1116027T1 CY 20151100147 T CY20151100147 T CY 20151100147T CY 151100147 T CY151100147 T CY 151100147T CY 1116027 T1 CY1116027 T1 CY 1116027T1
Authority
CY
Cyprus
Prior art keywords
mglur2
competitors
pyridine
pyrimidine derivatives
medicaments
Prior art date
Application number
CY20151100147T
Other languages
English (en)
Inventor
Mcarthur Silvia Gatti
Erwin Goetschi
Juergen Wichmann
Thomas Johannes Woltering
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36862654&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1116027(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of CY1116027T1 publication Critical patent/CY1116027T1/el

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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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Abstract

Η παρούσα εφεύρεση σχετίζεται με ενώσεις του τύπου (I), με μία διαδικασία για την παρασκευή αυτών, με τη χρήση τους για την παρασκευή φαρμάκων για τη θεραπευτική αντιμετώπιση διαταραχών του ΚΝΣ και με φαρμακευτικές συνθέσεις που τις περιέχουν: όπου τα Α, Β, Χ, Υ, R1, R2, R3 και R4 είναι όπως ορίζονται στην περιγραφή και τις αξιώσεις.
CY20151100147T 2006-03-29 2015-02-13 Παραγωγα πυριδινης και πυριμιδινης ως mglur2 ανταγωνιστες CY1116027T1 (el)

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