PT2231642E - Pirimidinas como inibidores de quinase - Google Patents

Pirimidinas como inibidores de quinase Download PDF

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Publication number
PT2231642E
PT2231642E PT97004527T PT09700452T PT2231642E PT 2231642 E PT2231642 E PT 2231642E PT 97004527 T PT97004527 T PT 97004527T PT 09700452 T PT09700452 T PT 09700452T PT 2231642 E PT2231642 E PT 2231642E
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PT
Portugal
Prior art keywords
pyrimidines
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
PT97004527T
Other languages
English (en)
Inventor
Catherine Leblanc
Nikolaus Johannes Stiefl
Peter Hunt
Robert Alexander Pulz
Original Assignee
Novartis Ag
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Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT2231642E publication Critical patent/PT2231642E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
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  • Communicable Diseases (AREA)
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  • Pain & Pain Management (AREA)
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PT97004527T 2008-01-11 2009-01-09 Pirimidinas como inibidores de quinase PT2231642E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08150194 2008-01-11
EP08157985 2008-06-10

Publications (1)

Publication Number Publication Date
PT2231642E true PT2231642E (pt) 2014-03-12

Family

ID=40551454

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97004527T PT2231642E (pt) 2008-01-11 2009-01-09 Pirimidinas como inibidores de quinase

Country Status (14)

Country Link
US (1) US8431578B2 (pt)
EP (1) EP2231642B1 (pt)
JP (1) JP5584138B2 (pt)
KR (1) KR20100113557A (pt)
CN (1) CN101910153B (pt)
AU (1) AU2009203693B2 (pt)
BR (1) BRPI0906838A2 (pt)
CA (1) CA2711637A1 (pt)
EA (1) EA201001129A1 (pt)
ES (1) ES2442930T3 (pt)
MX (1) MX2010007604A (pt)
PL (1) PL2231642T3 (pt)
PT (1) PT2231642E (pt)
WO (1) WO2009087224A1 (pt)

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JP2023533850A (ja) 2020-07-15 2023-08-04 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ Ａｌｋ５阻害剤としてのピリドオキサジンアミノ誘導体
EP4182308A1 (en) 2020-07-15 2023-05-24 Chiesi Farmaceutici S.p.A. Pyridazinyl amino derivatives as alk5 inhibitors
EP4267584A1 (en) 2020-12-23 2023-11-01 Chiesi Farmaceutici S.p.A. Pyrido oxazine derivatives as alk5 inhibitors
CA3232178A1 (en) 2021-09-21 2023-03-30 Daniela PIZZIRANI Pyridazinyl amino derivatives as alk5 inhibitors
WO2023135107A1 (en) * 2022-01-11 2023-07-20 Chiesi Farmaceutici S.P.A. Pyridazinyl amino derivatives as alk5 inhibitors
WO2023208986A1 (en) 2022-04-27 2023-11-02 Chiesi Farmaceutici S.P.A. Imidazole derivatives as alk5 inhibitors

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AU2009203693A1 (en) 2009-07-16
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US20100298337A1 (en) 2010-11-25
CN101910153A (zh) 2010-12-08
EA201001129A1 (ru) 2011-02-28
KR20100113557A (ko) 2010-10-21
US8431578B2 (en) 2013-04-30
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