CY1111837T1 - Μεθοδος για τη παρασκευη 3, 6-διυδρο-l,3,5- τριαζινο παραγωγων απο παραγωγα μετφορμινης και παραλδεϋδης - Google Patents
Μεθοδος για τη παρασκευη 3, 6-διυδρο-l,3,5- τριαζινο παραγωγων απο παραγωγα μετφορμινης και παραλδεϋδηςInfo
- Publication number
- CY1111837T1 CY1111837T1 CY20111100879T CY111100879T CY1111837T1 CY 1111837 T1 CY1111837 T1 CY 1111837T1 CY 20111100879 T CY20111100879 T CY 20111100879T CY 111100879 T CY111100879 T CY 111100879T CY 1111837 T1 CY1111837 T1 CY 1111837T1
- Authority
- CY
- Cyprus
- Prior art keywords
- producers
- preparation
- triumphine
- paralledid
- didhro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Μέθοδος για την παρασκευή ενώσεων του τύπου (I), εις τον οποίο τα R1, R2, R3, R4, R5 και R6 έχουν τις σημασίες που δίδονται εις την αξίωση 1, η οποία περιλαμβάνει την αντίδραση μιας ένωσης του τύπου (II), εις τον οποίο τα R1, R2, R3, R4 έχουν τις ανωτέρω δοθείσες σημασίες με μία ένωση του τύπου (III), εις τον οποίο τα R5, R6 έχουν τις ανωτέρω δοθείσες σημασίες.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008007314A DE102008007314A1 (de) | 2008-02-02 | 2008-02-02 | Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten |
| EP09705420A EP2240456B1 (de) | 2008-02-02 | 2009-01-15 | Verfahren zur herstellung von 3, 6-dihydro-l, 3, 5-triazinderivaten aus metformin- und paraldehydderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111837T1 true CY1111837T1 (el) | 2015-10-07 |
Family
ID=40459622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111100879T CY1111837T1 (el) | 2008-02-02 | 2011-09-13 | Μεθοδος για τη παρασκευη 3, 6-διυδρο-l,3,5- τριαζινο παραγωγων απο παραγωγα μετφορμινης και παραλδεϋδης |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8461331B2 (el) |
| EP (1) | EP2240456B1 (el) |
| JP (1) | JP5542066B2 (el) |
| KR (1) | KR101553568B1 (el) |
| CN (1) | CN101932566B (el) |
| AR (1) | AR070329A1 (el) |
| AT (1) | ATE519752T1 (el) |
| AU (1) | AU2009210293B2 (el) |
| BR (1) | BRPI0907052B8 (el) |
| CA (1) | CA2713236C (el) |
| CY (1) | CY1111837T1 (el) |
| DE (1) | DE102008007314A1 (el) |
| DK (1) | DK2240456T3 (el) |
| EA (1) | EA017062B1 (el) |
| ES (1) | ES2368116T3 (el) |
| HR (1) | HRP20110644T1 (el) |
| IL (1) | IL206816A (el) |
| MX (1) | MX2010008282A (el) |
| PL (1) | PL2240456T3 (el) |
| PT (1) | PT2240456E (el) |
| RS (1) | RS51968B (el) |
| SI (1) | SI2240456T1 (el) |
| WO (1) | WO2009095159A1 (el) |
| ZA (1) | ZA201006211B (el) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8742103B2 (en) | 2010-12-01 | 2014-06-03 | Poxel | Separation of triazine derivatives enantiomers using tartaric acid |
| WO2019069230A1 (en) | 2017-10-02 | 2019-04-11 | Poxel | METHODS OF TREATING CARDIAC INSUFFICIENCY WITH PRESERVED EJECTION FRACTION |
| CA3102412A1 (en) | 2018-06-06 | 2019-12-12 | Metavant Sciences Gmbh | Methods of treating subjects having diabetes with chronic kidney disease |
| EP3806828A1 (en) | 2018-06-14 | 2021-04-21 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
| CN109655544B (zh) * | 2018-12-25 | 2022-08-12 | 广东华南药业集团有限公司 | 一种盐酸二甲双胍及其制剂的质量控制方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1537604A (fr) | 1966-09-26 | 1968-08-23 | Sandoz Sa | Procédé de préparation de biguanides |
| GB1250531A (el) * | 1969-01-01 | 1971-10-20 | ||
| DE2117015A1 (de) | 1971-04-02 | 1972-10-26 | Schering Ag | 1,2-Biguanide |
| SU458538A1 (ru) * | 1973-06-14 | 1975-01-30 | Уфимский Нефтяной Институт | Способ совместного получени 1,3диеновых углеводородов и гексаметилентетрамина |
| JPH061779A (ja) * | 1992-02-06 | 1994-01-11 | Wakamoto Pharmaceut Co Ltd | ベンズオキサジノン誘導体 |
| US5767294A (en) * | 1993-02-17 | 1998-06-16 | Hoechst Celanese Corporation | Process for the production of trioxane from formaldehyde |
| US5627282A (en) * | 1996-01-03 | 1997-05-06 | Yukong Limited | Process for the preparation of optically pure 1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid and its derivatives |
| FR2804113B1 (fr) * | 2000-01-26 | 2004-06-18 | Lipha | Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique |
| CN100551916C (zh) * | 2002-12-17 | 2009-10-21 | 浜理药品工业株式会社 | 新的2,4-二氨基-1,3,5-三嗪衍生物 |
| MXPA05006450A (es) | 2002-12-17 | 2005-08-19 | Hamari Chemicals Ltd | Nuevo derivado de 2,4-diamino-1,3,5-triazina. |
| FR2853650B1 (fr) * | 2003-04-10 | 2006-07-07 | Merck Sante Sas | Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance |
| TWI410413B (zh) * | 2006-04-26 | 2013-10-01 | Sumitomo Seika Chemicals | Preparation method of methylene disulfonate compound |
-
2008
- 2008-02-02 DE DE102008007314A patent/DE102008007314A1/de not_active Withdrawn
-
2009
- 2009-01-15 AT AT09705420T patent/ATE519752T1/de active
- 2009-01-15 AU AU2009210293A patent/AU2009210293B2/en not_active Ceased
- 2009-01-15 ES ES09705420T patent/ES2368116T3/es active Active
- 2009-01-15 CA CA2713236A patent/CA2713236C/en active Active
- 2009-01-15 US US12/735,608 patent/US8461331B2/en active Active
- 2009-01-15 CN CN2009801039472A patent/CN101932566B/zh active Active
- 2009-01-15 EP EP09705420A patent/EP2240456B1/de active Active
- 2009-01-15 DK DK09705420.9T patent/DK2240456T3/da active
- 2009-01-15 EA EA201001252A patent/EA017062B1/ru not_active IP Right Cessation
- 2009-01-15 PT PT09705420T patent/PT2240456E/pt unknown
- 2009-01-15 SI SI200930069T patent/SI2240456T1/sl unknown
- 2009-01-15 MX MX2010008282A patent/MX2010008282A/es active IP Right Grant
- 2009-01-15 JP JP2010544612A patent/JP5542066B2/ja active Active
- 2009-01-15 RS RS20110409A patent/RS51968B/en unknown
- 2009-01-15 BR BRPI0907052A patent/BRPI0907052B8/pt not_active IP Right Cessation
- 2009-01-15 PL PL09705420T patent/PL2240456T3/pl unknown
- 2009-01-15 WO PCT/EP2009/000212 patent/WO2009095159A1/de active Application Filing
- 2009-01-15 KR KR1020107018199A patent/KR101553568B1/ko active IP Right Grant
- 2009-01-30 AR ARP090100299A patent/AR070329A1/es unknown
-
2010
- 2010-07-05 IL IL206816A patent/IL206816A/en active IP Right Grant
- 2010-08-31 ZA ZA2010/06211A patent/ZA201006211B/en unknown
-
2011
- 2011-09-07 HR HR20110644T patent/HRP20110644T1/hr unknown
- 2011-09-13 CY CY20111100879T patent/CY1111837T1/el unknown
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