PT2240456E - Método para produção de derivados de 3,6-di-hidro-l,3,5- triazina a partir de derivados de metformina e de paraldeído - Google Patents

Método para produção de derivados de 3,6-di-hidro-l,3,5- triazina a partir de derivados de metformina e de paraldeído Download PDF

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Publication number
PT2240456E
PT2240456E PT09705420T PT09705420T PT2240456E PT 2240456 E PT2240456 E PT 2240456E PT 09705420 T PT09705420 T PT 09705420T PT 09705420 T PT09705420 T PT 09705420T PT 2240456 E PT2240456 E PT 2240456E
Authority
PT
Portugal
Prior art keywords
derivatives
paraldehyde
metformin
dihydro
production
Prior art date
Application number
PT09705420T
Other languages
English (en)
Inventor
Matthias Helmreich
Mike Brandner
Original Assignee
Poxel Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poxel Sas filed Critical Poxel Sas
Publication of PT2240456E publication Critical patent/PT2240456E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
PT09705420T 2008-02-02 2009-01-15 Método para produção de derivados de 3,6-di-hidro-l,3,5- triazina a partir de derivados de metformina e de paraldeído PT2240456E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102008007314A DE102008007314A1 (de) 2008-02-02 2008-02-02 Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten

Publications (1)

Publication Number Publication Date
PT2240456E true PT2240456E (pt) 2011-09-27

Family

ID=40459622

Family Applications (1)

Application Number Title Priority Date Filing Date
PT09705420T PT2240456E (pt) 2008-02-02 2009-01-15 Método para produção de derivados de 3,6-di-hidro-l,3,5- triazina a partir de derivados de metformina e de paraldeído

Country Status (24)

Country Link
US (1) US8461331B2 (pt)
EP (1) EP2240456B1 (pt)
JP (1) JP5542066B2 (pt)
KR (1) KR101553568B1 (pt)
CN (1) CN101932566B (pt)
AR (1) AR070329A1 (pt)
AT (1) ATE519752T1 (pt)
AU (1) AU2009210293B2 (pt)
BR (1) BRPI0907052B8 (pt)
CA (1) CA2713236C (pt)
CY (1) CY1111837T1 (pt)
DE (1) DE102008007314A1 (pt)
DK (1) DK2240456T3 (pt)
EA (1) EA017062B1 (pt)
ES (1) ES2368116T3 (pt)
HR (1) HRP20110644T1 (pt)
IL (1) IL206816A (pt)
MX (1) MX2010008282A (pt)
PL (1) PL2240456T3 (pt)
PT (1) PT2240456E (pt)
RS (1) RS51968B (pt)
SI (1) SI2240456T1 (pt)
WO (1) WO2009095159A1 (pt)
ZA (1) ZA201006211B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2816357C (en) 2010-12-01 2015-04-28 Poxel Separation of triazine derivatives enantiomers using tartaric acid
MX2020003243A (es) 2017-10-02 2020-09-18 Poxel Métodos para tratar la insuficiencia cardíaca con fracción de eyección preservada.
ES2929994T3 (es) 2018-06-06 2022-12-05 Poxel Sa Métodos de tratamiento de sujetos que padecen diabetes con enfermedad renal crónica
MX2020013567A (es) 2018-06-14 2021-05-27 Poxel Tableta recubierta con pelicula que comprende un derivado de triazina para su uso en el tratamiento de la diabetes.
CN109655544B (zh) * 2018-12-25 2022-08-12 广东华南药业集团有限公司 一种盐酸二甲双胍及其制剂的质量控制方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1537604A (fr) 1966-09-26 1968-08-23 Sandoz Sa Procédé de préparation de biguanides
GB1250531A (pt) * 1969-01-01 1971-10-20
DE2117015A1 (de) 1971-04-02 1972-10-26 Schering Ag 1,2-Biguanide
SU458538A1 (ru) * 1973-06-14 1975-01-30 Уфимский Нефтяной Институт Способ совместного получени 1,3диеновых углеводородов и гексаметилентетрамина
JPH061779A (ja) * 1992-02-06 1994-01-11 Wakamoto Pharmaceut Co Ltd ベンズオキサジノン誘導体
US5767294A (en) * 1993-02-17 1998-06-16 Hoechst Celanese Corporation Process for the production of trioxane from formaldehyde
US5627282A (en) * 1996-01-03 1997-05-06 Yukong Limited Process for the preparation of optically pure 1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid and its derivatives
FR2804113B1 (fr) * 2000-01-26 2004-06-18 Lipha Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique
CN100551916C (zh) * 2002-12-17 2009-10-21 浜理药品工业株式会社 新的2,4-二氨基-1,3,5-三嗪衍生物
KR101027366B1 (ko) 2002-12-17 2011-04-11 하마리야꾸힝고오교가부시끼가이샤 신규한 2,4-디아미노-1,3,5-트리아진 유도체
FR2853650B1 (fr) * 2003-04-10 2006-07-07 Merck Sante Sas Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance
TWI410413B (zh) * 2006-04-26 2013-10-01 Sumitomo Seika Chemicals Preparation method of methylene disulfonate compound

Also Published As

Publication number Publication date
EA017062B1 (ru) 2012-09-28
US8461331B2 (en) 2013-06-11
HRP20110644T1 (hr) 2011-10-31
BRPI0907052A2 (pt) 2015-07-07
KR101553568B1 (ko) 2015-09-16
ATE519752T1 (de) 2011-08-15
RS51968B (en) 2012-02-29
SI2240456T1 (sl) 2012-01-31
MX2010008282A (es) 2010-11-30
EP2240456B1 (de) 2011-08-10
CN101932566A (zh) 2010-12-29
KR20100103698A (ko) 2010-09-27
JP5542066B2 (ja) 2014-07-09
CA2713236A1 (en) 2009-08-06
IL206816A (en) 2013-02-28
PL2240456T3 (pl) 2011-11-30
AU2009210293A1 (en) 2009-08-06
IL206816A0 (en) 2010-12-30
JP2011510940A (ja) 2011-04-07
DE102008007314A1 (de) 2009-08-06
WO2009095159A1 (de) 2009-08-06
CN101932566B (zh) 2013-04-10
US20110118463A1 (en) 2011-05-19
AR070329A1 (es) 2010-03-31
DK2240456T3 (da) 2011-09-26
EP2240456A1 (de) 2010-10-20
ZA201006211B (en) 2011-05-25
EA201001252A1 (ru) 2010-12-30
BRPI0907052B1 (pt) 2020-09-24
BRPI0907052B8 (pt) 2021-05-25
ES2368116T3 (es) 2011-11-14
CY1111837T1 (el) 2015-10-07
CA2713236C (en) 2016-03-22
AU2009210293B2 (en) 2013-05-23

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