PL2240456T3 - Sposób wytwarzania pochodnych 3,6-dihydro-1,3,5-triazyny z pochodnych metforminy i paraldehydu - Google Patents
Sposób wytwarzania pochodnych 3,6-dihydro-1,3,5-triazyny z pochodnych metforminy i paraldehyduInfo
- Publication number
- PL2240456T3 PL2240456T3 PL09705420T PL09705420T PL2240456T3 PL 2240456 T3 PL2240456 T3 PL 2240456T3 PL 09705420 T PL09705420 T PL 09705420T PL 09705420 T PL09705420 T PL 09705420T PL 2240456 T3 PL2240456 T3 PL 2240456T3
- Authority
- PL
- Poland
- Prior art keywords
- derivatives
- paraldehyde
- metformin
- dihydro
- production
- Prior art date
Links
- FIDRAVVQGKNYQK-UHFFFAOYSA-N 1,2,3,4-tetrahydrotriazine Chemical class C1NNNC=C1 FIDRAVVQGKNYQK-UHFFFAOYSA-N 0.000 title 1
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title 1
- 229960003105 metformin Drugs 0.000 title 1
- SQYNKIJPMDEDEG-UHFFFAOYSA-N paraldehyde Chemical class CC1OC(C)OC(C)O1 SQYNKIJPMDEDEG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008007314A DE102008007314A1 (de) | 2008-02-02 | 2008-02-02 | Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten |
| EP09705420A EP2240456B1 (de) | 2008-02-02 | 2009-01-15 | Verfahren zur herstellung von 3, 6-dihydro-l, 3, 5-triazinderivaten aus metformin- und paraldehydderivaten |
| PCT/EP2009/000212 WO2009095159A1 (de) | 2008-02-02 | 2009-01-15 | Verfahren zur herstellung von 3, 6-dihydro-l, 3, 5-triazinderivaten aus metformin- und paraldehydderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2240456T3 true PL2240456T3 (pl) | 2011-11-30 |
Family
ID=40459622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09705420T PL2240456T3 (pl) | 2008-02-02 | 2009-01-15 | Sposób wytwarzania pochodnych 3,6-dihydro-1,3,5-triazyny z pochodnych metforminy i paraldehydu |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8461331B2 (pl) |
| EP (1) | EP2240456B1 (pl) |
| JP (1) | JP5542066B2 (pl) |
| KR (1) | KR101553568B1 (pl) |
| CN (1) | CN101932566B (pl) |
| AR (1) | AR070329A1 (pl) |
| AT (1) | ATE519752T1 (pl) |
| AU (1) | AU2009210293B2 (pl) |
| BR (1) | BRPI0907052B8 (pl) |
| CA (1) | CA2713236C (pl) |
| CY (1) | CY1111837T1 (pl) |
| DE (1) | DE102008007314A1 (pl) |
| DK (1) | DK2240456T3 (pl) |
| EA (1) | EA017062B1 (pl) |
| ES (1) | ES2368116T3 (pl) |
| HR (1) | HRP20110644T1 (pl) |
| IL (1) | IL206816A (pl) |
| MX (1) | MX2010008282A (pl) |
| PL (1) | PL2240456T3 (pl) |
| PT (1) | PT2240456E (pl) |
| RS (1) | RS51968B (pl) |
| SI (1) | SI2240456T1 (pl) |
| WO (1) | WO2009095159A1 (pl) |
| ZA (1) | ZA201006211B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS54397B1 (sr) | 2010-12-01 | 2016-04-28 | Poxel | Odvajanje enantiomera triazin derivata pomoću vinske kiseline |
| US11617754B2 (en) | 2017-10-02 | 2023-04-04 | Poxel Sa | Methods of treating heart failure with preserved ejection fraction |
| MX2020013210A (es) | 2018-06-06 | 2021-02-26 | Metavant Sciences Gmbh | Metodos de tratamiento de sujetos que padecen diabetes con enfermedad renal cronica. |
| EP3806828A1 (en) | 2018-06-14 | 2021-04-21 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
| CN109655544B (zh) * | 2018-12-25 | 2022-08-12 | 广东华南药业集团有限公司 | 一种盐酸二甲双胍及其制剂的质量控制方法 |
| WO2025233968A1 (en) * | 2024-05-10 | 2025-11-13 | Council Of Scientific And Industrial Research | A process for the preparation of imeglimin compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1537604A (fr) | 1966-09-26 | 1968-08-23 | Sandoz Sa | Procédé de préparation de biguanides |
| GB1250531A (pl) * | 1969-01-01 | 1971-10-20 | ||
| DE2117015A1 (de) | 1971-04-02 | 1972-10-26 | Schering Ag | 1,2-Biguanide |
| SU458538A1 (ru) * | 1973-06-14 | 1975-01-30 | Уфимский Нефтяной Институт | Способ совместного получени 1,3диеновых углеводородов и гексаметилентетрамина |
| JPH061779A (ja) * | 1992-02-06 | 1994-01-11 | Wakamoto Pharmaceut Co Ltd | ベンズオキサジノン誘導体 |
| US5767294A (en) * | 1993-02-17 | 1998-06-16 | Hoechst Celanese Corporation | Process for the production of trioxane from formaldehyde |
| US5627282A (en) * | 1996-01-03 | 1997-05-06 | Yukong Limited | Process for the preparation of optically pure 1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid and its derivatives |
| FR2804113B1 (fr) * | 2000-01-26 | 2004-06-18 | Lipha | Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique |
| CN100551916C (zh) * | 2002-12-17 | 2009-10-21 | 浜理药品工业株式会社 | 新的2,4-二氨基-1,3,5-三嗪衍生物 |
| BRPI0317188A8 (pt) * | 2002-12-17 | 2018-05-08 | Hamari Chemicals Ltd | novo derivado de 2,4-diamino-1,3,5-triazina |
| FR2853650B1 (fr) * | 2003-04-10 | 2006-07-07 | Merck Sante Sas | Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance |
| TWI410413B (zh) * | 2006-04-26 | 2013-10-01 | Sumitomo Seika Chemicals | Preparation method of methylene disulfonate compound |
-
2008
- 2008-02-02 DE DE102008007314A patent/DE102008007314A1/de not_active Withdrawn
-
2009
- 2009-01-15 MX MX2010008282A patent/MX2010008282A/es active IP Right Grant
- 2009-01-15 PL PL09705420T patent/PL2240456T3/pl unknown
- 2009-01-15 WO PCT/EP2009/000212 patent/WO2009095159A1/de not_active Ceased
- 2009-01-15 PT PT09705420T patent/PT2240456E/pt unknown
- 2009-01-15 US US12/735,608 patent/US8461331B2/en not_active Expired - Fee Related
- 2009-01-15 HR HR20110644T patent/HRP20110644T1/hr unknown
- 2009-01-15 EP EP09705420A patent/EP2240456B1/de active Active
- 2009-01-15 AU AU2009210293A patent/AU2009210293B2/en not_active Ceased
- 2009-01-15 SI SI200930069T patent/SI2240456T1/sl unknown
- 2009-01-15 DK DK09705420.9T patent/DK2240456T3/da active
- 2009-01-15 AT AT09705420T patent/ATE519752T1/de active
- 2009-01-15 EA EA201001252A patent/EA017062B1/ru not_active IP Right Cessation
- 2009-01-15 RS RS20110409A patent/RS51968B/sr unknown
- 2009-01-15 BR BRPI0907052A patent/BRPI0907052B8/pt not_active IP Right Cessation
- 2009-01-15 KR KR1020107018199A patent/KR101553568B1/ko active Active
- 2009-01-15 JP JP2010544612A patent/JP5542066B2/ja active Active
- 2009-01-15 CA CA2713236A patent/CA2713236C/en active Active
- 2009-01-15 ES ES09705420T patent/ES2368116T3/es active Active
- 2009-01-15 CN CN2009801039472A patent/CN101932566B/zh active Active
- 2009-01-30 AR ARP090100299A patent/AR070329A1/es unknown
-
2010
- 2010-07-05 IL IL206816A patent/IL206816A/en active IP Right Grant
- 2010-08-31 ZA ZA2010/06211A patent/ZA201006211B/en unknown
-
2011
- 2011-09-13 CY CY20111100879T patent/CY1111837T1/el unknown
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