CY1111210T1 - Μεταλλαγμενο στελεχος actinosynnema pretiosum με αυξημενη παραγωγη μαϋτανσινοειδους - Google Patents

Μεταλλαγμενο στελεχος actinosynnema pretiosum με αυξημενη παραγωγη μαϋτανσινοειδους

Info

Publication number
CY1111210T1
CY1111210T1 CY20101100876T CY101100876T CY1111210T1 CY 1111210 T1 CY1111210 T1 CY 1111210T1 CY 20101100876 T CY20101100876 T CY 20101100876T CY 101100876 T CY101100876 T CY 101100876T CY 1111210 T1 CY1111210 T1 CY 1111210T1
Authority
CY
Cyprus
Prior art keywords
maitansinoid
stein
actinosynnema pretiosum
metal stainless
growth production
Prior art date
Application number
CY20101100876T
Other languages
Greek (el)
English (en)
Inventor
Johnson Chung
Graham S Byng
Original Assignee
Immunogen, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunogen, Inc. filed Critical Immunogen, Inc.
Publication of CY1111210T1 publication Critical patent/CY1111210T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CY20101100876T 2002-01-29 2010-09-30 Μεταλλαγμενο στελεχος actinosynnema pretiosum με αυξημενη παραγωγη μαϋτανσινοειδους CY1111210T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/057,561 US6790954B2 (en) 2002-01-29 2002-01-29 Mutant Actinosynnema pretiosum strain with increased maytansinoid production
EP03734944A EP1468077B1 (en) 2002-01-29 2003-01-15 Mutant actinosynnema pretiosum strain with increased maytansinoid production

Publications (1)

Publication Number Publication Date
CY1111210T1 true CY1111210T1 (el) 2015-06-11

Family

ID=27658220

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100876T CY1111210T1 (el) 2002-01-29 2010-09-30 Μεταλλαγμενο στελεχος actinosynnema pretiosum με αυξημενη παραγωγη μαϋτανσινοειδους

Country Status (14)

Country Link
US (2) US6790954B2 (enExample)
EP (1) EP1468077B1 (enExample)
JP (3) JP4485799B2 (enExample)
AT (1) ATE474043T1 (enExample)
AU (1) AU2003238752B2 (enExample)
CA (1) CA2474639C (enExample)
CY (1) CY1111210T1 (enExample)
DE (1) DE60333340D1 (enExample)
DK (1) DK1468077T3 (enExample)
ES (1) ES2348865T3 (enExample)
NZ (1) NZ532831A (enExample)
PT (1) PT1468077E (enExample)
SI (1) SI1468077T1 (enExample)
WO (1) WO2003064610A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE446317T1 (de) 2001-05-11 2009-11-15 Ludwig Inst For Cancer Res Ltd Spezifische bindungsproteine und ihre verwendung
US20100056762A1 (en) 2001-05-11 2010-03-04 Old Lloyd J Specific binding proteins and uses thereof
US6790954B2 (en) * 2002-01-29 2004-09-14 Immunogen, Inc. Mutant Actinosynnema pretiosum strain with increased maytansinoid production
US7432088B2 (en) * 2003-05-08 2008-10-07 Immunogen Inc. Methods for the production of ansamitocins
CN101711284A (zh) 2007-01-25 2010-05-19 达娜-法勃肿瘤研究所 抗egfr抗体在治疗egfr突变体介导的疾病中的用途
ES2542152T3 (es) 2007-03-15 2015-07-31 Ludwig Institute For Cancer Research Ltd. Método de tratamiento que emplea anticuerpos de EGFR e inhibidores de Src y formulaciones relacionadas
US20090011060A1 (en) * 2007-07-06 2009-01-08 Peter Koepke Campsiandra angustifolia extract and methods of extracting and using such extract
US20090017140A1 (en) * 2007-07-09 2009-01-15 Peter Koepke Maytenus abenfolia extract and methods of extracting and using such extract
US20090035395A1 (en) * 2007-08-01 2009-02-05 Peter Koepke Spondias mombin l. extract and methods of extracting and using such extract
WO2009023265A1 (en) 2007-08-14 2009-02-19 Ludwig Institute For Cancer Research Monoclonal antibody 175 targeting the egf receptor and derivatives and uses thereof
US7879369B2 (en) * 2007-09-18 2011-02-01 Selvamedica, Llc Combretum laurifolium Mart. extract and methods of extracting and using such extract
KR20160125535A (ko) 2008-03-18 2016-10-31 제넨테크, 인크. 항-ｈｅｒ２ 항체-약물 접합체와 화학요법제의 병용물, 및 사용 방법
US20110076232A1 (en) * 2009-09-29 2011-03-31 Ludwig Institute For Cancer Research Specific binding proteins and uses thereof
AR079256A1 (es) 2009-12-04 2012-01-04 Genentech Inc Metodo para el tratamiento del cancer de mama metastasico con trastuzumab-mcc-dm1
TW201129384A (en) 2010-02-10 2011-09-01 Immunogen Inc CD20 antibodies and uses thereof
CA2816426A1 (en) 2010-11-17 2012-06-07 Genentech, Inc. Alaninyl maytansinol antibody conjugates
CN113607945B (zh) 2015-07-07 2025-01-28 豪夫迈·罗氏有限公司 抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法
CN108330113B (zh) * 2018-03-08 2019-05-28 山东省医药生物技术研究中心（山东省病毒研究所） 一株高底物专一性酰基转移酶的珍贵束丝放线菌及其应用
SI3956332T1 (sl) 2019-04-18 2023-05-31 Indena S.P.A. Diasteroselektivni postopek za pripravo tiol- ali disulfid-vsebujočih majtansinoidnih estrov in njihovih intermediatov
CN115322918B (zh) * 2021-05-11 2024-03-29 浙江珲达生物科技有限公司 一种高产安丝菌素p-3的菌株及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6016236B2 (ja) * 1977-11-18 1985-04-24 武田薬品工業株式会社 抗生物質ｃ―１５００３ ｐ―３の製造法
JPS5645483A (en) * 1979-09-19 1981-04-25 Takeda Chem Ind Ltd C-15003phm and its preparation
JPS56102793A (en) * 1979-12-28 1981-08-17 Takeda Chem Ind Ltd Preparation of antibiotic c-15003 p-3
JPS626673A (ja) * 1985-07-04 1987-01-13 Zenkoku Nogyo Kyodo Kumiai Rengokai パスツレラ・ムルトシダ変異株、生菌ワクチン及びその菌株の取得法
US5250435A (en) 1991-06-04 1993-10-05 Merck & Co., Inc. Mutant strains of Aspergillus terreus for producing 7-[1,2,6,7,8,8a(R)-hexa-hydro-2(S),6(R)-dimethyl-8(S)-hydroxy-1(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid),I)
ES2115637T3 (es) 1991-12-17 1998-07-01 Gist Brocades Nv Cepas de phaffia rhodozyma que tienen una alta concentracion intracelular de astaxantina y una baja concentracion intracelular de hdco.
JPH07274978A (ja) * 1994-04-13 1995-10-24 Bio Kosumosu:Kk 紅麹色素の製造方法
JP3376859B2 (ja) * 1996-11-27 2003-02-10 三菱化学株式会社 リビトールの製造方法
US6949356B1 (en) 1999-10-20 2005-09-27 Microbia, Inc. Methods for improving secondary metabolite production in fungi
US6573074B2 (en) * 2000-04-12 2003-06-03 Smithkline Beecham Plc Methods for ansamitocin production
US6790954B2 (en) * 2002-01-29 2004-09-14 Immunogen, Inc. Mutant Actinosynnema pretiosum strain with increased maytansinoid production

Also Published As

Publication number Publication date
CA2474639A1 (en) 2003-08-07
EP1468077B1 (en) 2010-07-14
US6790954B2 (en) 2004-09-14
NZ532831A (en) 2009-05-31
EP1468077A4 (en) 2006-06-07
JP5840656B2 (ja) 2016-01-06
WO2003064610A2 (en) 2003-08-07
JP2005519594A (ja) 2005-07-07
ES2348865T3 (es) 2010-12-16
US20030157694A1 (en) 2003-08-21
CA2474639C (en) 2015-08-04
SI1468077T1 (sl) 2010-11-30
US7192750B2 (en) 2007-03-20
DE60333340D1 (de) 2010-08-26
JP2013230163A (ja) 2013-11-14
WO2003064610A3 (en) 2004-01-22
PT1468077E (pt) 2010-10-12
ATE474043T1 (de) 2010-07-15
JP4485799B2 (ja) 2010-06-23
EP1468077A2 (en) 2004-10-20
US20050003513A1 (en) 2005-01-06
JP2010110328A (ja) 2010-05-20
AU2003238752B2 (en) 2008-05-29
DK1468077T3 (da) 2010-10-25

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