CY1110815T1 - Μη-συστρεφομενα πολυυδροξυαλκανοϊκα ραμματα - Google Patents

Μη-συστρεφομενα πολυυδροξυαλκανοϊκα ραμματα

Info

Publication number
CY1110815T1
CY1110815T1 CY20101100886T CY101100886T CY1110815T1 CY 1110815 T1 CY1110815 T1 CY 1110815T1 CY 20101100886 T CY20101100886 T CY 20101100886T CY 101100886 T CY101100886 T CY 101100886T CY 1110815 T1 CY1110815 T1 CY 1110815T1
Authority
CY
Cyprus
Prior art keywords
break
knot
strength
properties
polyhydroxylanic
Prior art date
Application number
CY20101100886T
Other languages
English (en)
Inventor
Said Rizk
Original Assignee
Tepha, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tepha, Inc. filed Critical Tepha, Inc.
Publication of CY1110815T1 publication Critical patent/CY1110815T1/el

Links

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/58—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products
    • D01F6/62—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters
    • D01F6/625—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters derived from hydroxy-carboxylic acids, e.g. lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A61L17/105—Polyesters not covered by A61L17/12
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/10—Scrim [e.g., open net or mesh, gauze, loose or open weave or knit, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Textile Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

Απορροφήσιμες πολυεστερικές ίνες, ταινιοπλέγματα, και χειρουργικά πλέγματα με βελτιωμένες ιδιότητες χειρισμού έχουν αναπτυχθεί. Αυτές οι συσκευές προέρχονται κατά προτίμηση από βιοσυμβατά συμπολυμερή ή ομοπολυμερή 4-υδροξυβουτυρικού εστέρα. Αυτές οι συσκευές παρέχουν ένα πλατύτερο εύρος ιδιοτήτων in vivo αντοχής συγκράτησης από εκείνες οι οποίες είναι επί του παρόντος διαθέσιμες και έχουν μια μειωμένη τάση να συστρέφονται, στην προτιμητέα υλοποίηση, εξαιτίας της συμπερίληψης σταδίων χαλάρωσης και ανόπτησης μετά από εξώθηση και προσανατολισμό της ίνας. Νήματα παρασκευασμένα σύμφωνα με αυτές τις μεθόδους χαρακτηρίζονται από τις ακόλουθες φυσικές ιδιότητες: επιμήκυνση θραύσης από περίπου 17% έως περίπου 85% (ii) μέτρο ελαστικότητας του Young μικρότερο από 350,000 psi, (iii) αναλογία κόμπου προς ευθύγραμμο (αντοχή κόμπου/αντοχή σε εφελκυσμό) 55-80% ή (iv) φορτίο θραύσης από 1100 έως 4200 γραμμάρια.
CY20101100886T 2004-08-03 2010-10-06 Μη-συστρεφομενα πολυυδροξυαλκανοϊκα ραμματα CY1110815T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59829604P 2004-08-03 2004-08-03
EP20050807559 EP1778305B1 (en) 2004-08-03 2005-07-29 Non-curling polyhydroxyalkanoate sutures

Publications (1)

Publication Number Publication Date
CY1110815T1 true CY1110815T1 (el) 2015-06-10

Family

ID=35636645

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100886T CY1110815T1 (el) 2004-08-03 2010-10-06 Μη-συστρεφομενα πολυυδροξυαλκανοϊκα ραμματα

Country Status (10)

Country Link
US (2) US7641825B2 (el)
EP (2) EP1778305B1 (el)
AT (2) ATE473021T1 (el)
CY (1) CY1110815T1 (el)
DE (1) DE602005022197D1 (el)
DK (1) DK1778305T3 (el)
ES (2) ES2362217T3 (el)
PL (1) PL1778305T3 (el)
PT (1) PT1778305E (el)
WO (1) WO2006015276A2 (el)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5931855A (en) 1997-05-21 1999-08-03 Frank Hoffman Surgical methods using one-way suture
EP1867348B1 (en) * 1999-03-25 2012-05-16 Metabolix, Inc. Medical devices and applications of polyhydroxyalkanoate polymers
US6773450B2 (en) 2002-08-09 2004-08-10 Quill Medical, Inc. Suture anchor and method
DK1638615T3 (en) 2003-05-08 2015-01-12 Tepha Inc MEDICAL POLYHYDROXYALKANOATE TEXTILES AND FIBERS
CA2531833C (en) * 2003-07-08 2009-10-20 Tepha, Inc. Poly-4-hydroxybutyrate matrices for sustained drug delivery
EP1663017A1 (en) * 2003-08-22 2006-06-07 Tepha, Inc. Polyhydroxyalkanoate nerve regeneration devices
NZ588140A (en) 2004-05-14 2012-05-25 Quill Medical Inc Suture methods and device using an enlongated body with cut barbs and a needle at one end and a loop at the other
ATE473021T1 (de) * 2004-08-03 2010-07-15 Tepha Inc Nichtkräuselnde polyhydroxyalkanoatnähte
FR2893325B1 (fr) * 2005-11-15 2010-04-02 Arkema Procede de preparation de polyhydroxyalkanoates polymeres ainsi obtenus, compositions les comprenant et leurs utilisations
IL177550A0 (en) * 2006-08-17 2006-12-31 Sialo Technology Israel Ltd All-in-one optical microscopic handle
US7943683B2 (en) * 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
US8915943B2 (en) * 2007-04-13 2014-12-23 Ethicon, Inc. Self-retaining systems for surgical procedures
EP2550978B1 (en) * 2007-09-27 2014-04-30 Ethicon, LLC A system for cutting a retainer in a suture
US20090112259A1 (en) * 2007-10-31 2009-04-30 Angiotech Pharmaceuticals, Inc. Recombinant expressed bioadsorbable polyhydroxyalkonate monofilament and multi-filaments self-retaining sutures
WO2009085823A1 (en) * 2007-12-19 2009-07-09 Tepha, Inc. Medical devices containing melt-blown non-wovens of poly-r-hydroxybutyrate and copolymers
US8916077B1 (en) 2007-12-19 2014-12-23 Ethicon, Inc. Self-retaining sutures with retainers formed from molten material
BRPI0820129B8 (pt) 2007-12-19 2021-06-22 Angiotech Pharm Inc processo de formação de uma sutura autorretentora e sutura autorretentora
US8118834B1 (en) 2007-12-20 2012-02-21 Angiotech Pharmaceuticals, Inc. Composite self-retaining sutures and method
US8615856B1 (en) 2008-01-30 2013-12-31 Ethicon, Inc. Apparatus and method for forming self-retaining sutures
WO2009097556A2 (en) 2008-01-30 2009-08-06 Angiotech Pharmaceuticals, Inc. Appartaus and method for forming self-retaining sutures
BRPI0907787B8 (pt) 2008-02-21 2021-06-22 Angiotech Pharm Inc método para formar uma sutura de autorretenção e aparelho para elevar os retentores em um fio de sutura a um ângulo desejado
US8641732B1 (en) 2008-02-26 2014-02-04 Ethicon, Inc. Self-retaining suture with variable dimension filament and method
WO2009129251A2 (en) 2008-04-15 2009-10-22 Angiotech Pharmaceuticals, Inc. Self-retaining sutures with bi-directional retainers or uni-directional retainers
MX2010013656A (es) 2008-06-12 2011-01-14 3M Innovative Properties Co Composiciones hidrofilicas biocompatibles.
US20110189463A1 (en) * 2008-06-12 2011-08-04 Moore Eric M Melt blown fine fibers and methods of manufacture
AU2013263831B2 (en) * 2008-06-12 2016-07-07 3M Innovative Properties Company Melt blown fine fibers and methods of manufacture
US8932328B2 (en) 2008-11-03 2015-01-13 Ethicon, Inc. Length of self-retaining suture and method and device for using the same
CN102439210B (zh) 2009-03-31 2015-12-16 3M创新有限公司 尺寸上稳定的非织造纤维幅材及其制造和使用方法
BR112012014963A2 (pt) * 2009-12-17 2018-06-05 3M Innovative Properties Co mantas fibrosas não tecidas dimensionalmente estáveis e métodos de fabricação e uso das mesmas
BR112012014945A2 (pt) 2009-12-17 2018-10-09 3M Innovative Properties Co manta fibrosa não tecida dimensionalmente estável, fibras finas produzidas por sopro em fusão (meltblown), e métodos de fabricação e uso das mesmas
WO2011090628A2 (en) 2009-12-29 2011-07-28 Angiotech Pharmaceuticals, Inc. Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods
WO2011119742A2 (en) 2010-03-26 2011-09-29 Tepha, Inc. Coatings for the manufacture and application of polyhydroxyalkanoate medical devices
US20130180966A1 (en) 2010-05-04 2013-07-18 Jeffrey M. Gross Laser cutting system and methods for creating self-retaining sutures
MX337815B (es) 2010-06-11 2016-03-18 Ethicon Llc Herramientas para dispensar suturas para cirugía endoscópica y asistida por robot y métodos.
CA2802212C (en) 2010-06-15 2015-03-24 Tepha, Inc. Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers
US9511169B2 (en) 2010-06-15 2016-12-06 Tepha, Inc. Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers with anisotropic properties
EP2425865A1 (en) * 2010-08-06 2012-03-07 Aesculap AG Medicinal thread having a polyhydroxyalkanoate coating
TW201221714A (en) 2010-10-14 2012-06-01 3M Innovative Properties Co Dimensionally stable nonwoven fibrous webs and methods of making and using the same
MX2013005072A (es) 2010-11-03 2013-12-02 Tissuegen Inc Hilos de sutura de autorretención eluyentes de fármacos y métodos relacionados con estos.
WO2012064902A2 (en) 2010-11-09 2012-05-18 Angiotech Pharmaceuticals, Inc. Emergency self-retaining sutures and packaging
CN102108562B (zh) * 2010-11-16 2013-02-13 清华大学 一种聚羟基脂肪酸酯纤维的制备方法
WO2012129534A2 (en) 2011-03-23 2012-09-27 Angiotech Pharmaceuticals, Inc. Self-retaining variable loop sutures
US20130172931A1 (en) 2011-06-06 2013-07-04 Jeffrey M. Gross Methods and devices for soft palate tissue elevation procedures
US9370482B1 (en) 2011-09-09 2016-06-21 Harrison Yu Method of incorporating additives to shaped porous monocomponent biopolymer fibers during fiber orienting step
WO2013146788A1 (ja) * 2012-03-27 2013-10-03 国立大学法人名古屋大学 ポリヒドロキシアルカノエートを含む材料から作製された３次元構造体、骨充填材の調製用キット、及び髄内釘
WO2013176734A1 (en) 2012-05-21 2013-11-28 Tepha, Inc. Resorbable bioceramic compositions of poly-4-hydroxybutyrate and copolymers
EP2945655B1 (en) 2013-01-15 2019-09-25 Tepha, Inc. Implants for soft and hard tissue regeneration
US9290612B2 (en) 2013-03-13 2016-03-22 Tepha, Inc. Compositions and devices of poly-4-hydroxybutyrate
US10201640B2 (en) 2013-03-13 2019-02-12 Tepha, Inc. Ultrafine electrospun fibers of poly-4-hydroxybutyrate and copolymers thereof
ES2878122T3 (es) 2013-08-20 2021-11-18 Tepha Inc Espumas de celda cerrada que incluyen poli-4-hidroxibutirato y copolímeros del mismo
US9687585B2 (en) 2013-08-20 2017-06-27 Tepha, Inc. Thermoformed poly-4-hydroxybutyrate medical implants
US9302029B2 (en) 2013-10-31 2016-04-05 Tepha, Inc. Pultrusion of poly-4-hydroxybutyrate and copolymers thereof
US9480780B2 (en) 2013-11-05 2016-11-01 Tepha, Inc. Compositions and devices of poly-4-hydroxybutyrate
EP3082617B1 (en) 2013-12-19 2022-11-16 Tornier, Inc. High-strength bioabsorbable suture
CA2933746C (en) 2013-12-26 2018-12-04 Tepha, Inc. Medical implants including laminates of poly-4-hydroxybutyrate and copolymers thereof
ES2685963T3 (es) 2014-03-18 2018-10-15 Tepha, Inc. Bandas de microfibras de poli-4-hidroxibutirato y sus copolímeros producidas por hilado centrífugo
CA2947141C (en) 2014-04-30 2019-01-15 Tepha, Inc. Three-dimensional resorbable implants for tissue reinforcement and hernia repair
ES2807178T3 (es) 2014-08-15 2021-02-22 Tepha Inc Suturas de autorretención de poli-4-hidroxibutirato y copolímeros del mismo
CA2958544C (en) 2014-08-20 2019-05-21 Tepha, Inc. Thermoformed poly-4-hydroxybutyrate medical implants
ES2802383T3 (es) 2014-09-22 2021-01-19 Tepha Inc Implantes de P4HB orientados que contienen agentes antimicrobianos
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
CA2969429C (en) 2014-12-11 2020-10-27 Tepha, Inc. Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof
CA3064729C (en) 2017-05-25 2022-03-29 Tepha, Inc. Continuous formation of tubes of poly-4-hydroxybutyrate and copolymers thereof
CA3074733C (en) 2017-09-06 2022-06-21 Tepha, Inc. Calendered surgical meshes comprising polyhydroxyalkanoates
EP3720514B1 (en) 2017-12-04 2022-04-13 Tepha, Inc. Vacuum membrane thermoformed poly-4-hydroxybutyrate medical implants
CA3102277A1 (en) 2018-06-11 2019-12-19 Tepha, Inc. Methods for 3d printing of poly-4-hydroxybutyrate and copolymers
ES2956815T3 (es) 2018-10-29 2023-12-28 Tepha Inc Procedimientos de fabricación de suturas de malla a partir de poli-4-hidroxibutirato y sus copolímeros

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3731683A (en) * 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US3982543A (en) * 1973-04-24 1976-09-28 American Cyanamid Company Reducing capillarity of polyglycolic acid sutures
US4031894A (en) * 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4205399A (en) * 1977-06-13 1980-06-03 Ethicon, Inc. Synthetic absorbable surgical devices of poly(alkylene oxalates)
US4201211A (en) * 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4849226A (en) * 1981-06-29 1989-07-18 Alza Corporation Method for increasing oxygen supply by administering vasodilator
US4435180A (en) * 1982-05-25 1984-03-06 Alza Corporation Elastomeric active agent delivery system and method of use
DE3374698D1 (en) * 1982-08-27 1988-01-07 Ici Plc 3-hydroxybutyrate polymers
US4559222A (en) 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
US4856188A (en) * 1984-10-12 1989-08-15 Drug Delivery Systems Inc. Method for making disposable and/or replenishable transdermal drug applicators
EP0145233B2 (en) * 1983-11-23 1991-11-06 Imperial Chemical Industries Plc Separation processfor a 3-hydroxybutyrate polymer
US4704282A (en) 1984-06-29 1987-11-03 Alza Corporation Transdermal therapeutic system having improved delivery characteristics
US4588580B2 (en) * 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
GB8424950D0 (en) * 1984-10-03 1984-11-07 Ici Plc Non-woven fibrous materials
US4573995A (en) * 1984-10-09 1986-03-04 Alza Corporation Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine
GB2166354B (en) 1984-10-10 1987-12-09 Ici Plc Wound dressings
US4648978A (en) * 1985-04-24 1987-03-10 American Sterilizer Company Process for the continuous preparation of sterile, depyrogenated solutions
US4645502A (en) * 1985-05-03 1987-02-24 Alza Corporation Transdermal delivery of highly ionized fat insoluble drugs
AU603076B2 (en) * 1985-12-09 1990-11-08 W.R. Grace & Co.-Conn. Polymeric products and their manufacture
US4792336A (en) 1986-03-03 1988-12-20 American Cyanamid Company Flat braided ligament or tendon implant device having texturized yarns
US4664655A (en) * 1986-03-20 1987-05-12 Norman Orentreich High viscosity fluid delivery system
US4758234A (en) * 1986-03-20 1988-07-19 Norman Orentreich High viscosity fluid delivery system
US5032638A (en) * 1986-09-05 1991-07-16 American Cyanamid Company Bioabsorbable coating for a surgical device
US4711241A (en) 1986-09-05 1987-12-08 American Cyanamid Company Surgical filament coating
US4908027A (en) * 1986-09-12 1990-03-13 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
JPH0725689B2 (ja) * 1986-10-07 1995-03-22 中外製薬株式会社 顆粒球コロニ−刺激因子を含有する徐放性製剤
NL8603073A (nl) * 1986-12-02 1988-07-01 Rijksuniversiteit Werkwijze voor het bereiden van polyesters door fermentatie; werkwijze voor het bereiden van optisch actieve carbonzuren en esters; polyester omvattende voortbrengselen.
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
US4788062A (en) 1987-02-26 1988-11-29 Alza Corporation Transdermal administration of progesterone, estradiol esters, and mixtures thereof
US5059211A (en) * 1987-06-25 1991-10-22 Duke University Absorbable vascular stent
US5250430A (en) 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
US5480794A (en) * 1987-06-29 1996-01-02 Massachusetts Institute Of Technology And Metabolix, Inc. Overproduction and purification of soluble PHA synthase
US5245023A (en) * 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US5229279A (en) * 1987-06-29 1993-07-20 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
SE8802414D0 (sv) 1988-06-27 1988-06-28 Astra Meditec Ab Nytt kirurgiskt material
US4943435A (en) * 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
IT1217783B (it) 1988-06-03 1990-03-30 Farmaceutico Ct S R L Lab Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative
US5502158A (en) 1988-08-08 1996-03-26 Ecopol, Llc Degradable polymer composition
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5085629A (en) * 1988-10-06 1992-02-04 Medical Engineering Corporation Biodegradable stent
US5026381A (en) * 1989-04-20 1991-06-25 Colla-Tec, Incorporated Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit
US5041100A (en) * 1989-04-28 1991-08-20 Cordis Corporation Catheter and hydrophilic, friction-reducing coating thereon
US5002067A (en) * 1989-08-23 1991-03-26 Medtronic, Inc. Medical electrical lead employing improved penetrating electrode
EP0423484B1 (de) 1989-10-16 1993-11-03 PCD-Polymere Gesellschaft m.b.H. Pressling mit retardierter Wirkstofffreisetzung
IT1238344B (it) 1989-10-20 1993-07-13 Sigma Tau Ind Farmaceuti Estere della l-carnitina con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che lo contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma
US5271961A (en) 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
DE3937649A1 (de) 1989-11-11 1991-05-16 Boehringer Ingelheim Kg Polyester auf der basis von 4-hydroxyalkansaeuren und verfahren zu ihrer herstellung
JPH0662839B2 (ja) * 1989-11-14 1994-08-17 工業技術院長 微生物分解性プラスチック成形物及びその製造方法
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
EP0452111B1 (en) 1990-04-13 1998-07-15 Takeda Chemical Industries, Ltd. Biodegradable high-molecular polymers, production and use thereof
US5171308A (en) * 1990-05-11 1992-12-15 E. I. Du Pont De Nemours And Company Polyesters and their use in compostable products such as disposable diapers
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
IT1247157B (it) * 1991-02-11 1994-12-12 Fidia Spa Canali di guida biodegradabili e bioassorbibili da impiegare per la rigenerazione nervosa.
CA2064410A1 (en) 1991-04-01 1992-10-02 Masanobu Ajioka Degradable foam and use of same
DE4113984C2 (de) * 1991-04-29 2002-05-08 Koehler Chemie Dr Franz Salze der 4-Hydroxy-Buttersäure
FR2676927B1 (fr) * 1991-05-29 1995-06-23 Ibf Microspheres utilisables pour les occlusions vasculaires therapeutiques et solutions injectables les contenant.
US5236431A (en) * 1991-07-22 1993-08-17 Synthes Resorbable fixation device with controlled stiffness for treating bodily material in vivo and introducer therefor
JP2777757B2 (ja) * 1991-09-17 1998-07-23 鐘淵化学工業株式会社 共重合体およびその製造方法
EP0560984B1 (en) * 1991-09-27 1999-05-26 Terumo Kabushiki Kaisha Flexible member for medical use
WO1993006792A1 (en) 1991-10-04 1993-04-15 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
US5204382A (en) * 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
CH689767A5 (de) * 1992-03-24 1999-10-15 Balzers Hochvakuum Verfahren zur Werkstueckbehandlung in einer Vakuumatmosphaere und Vakuumbehandlungsanlage.
US5939467A (en) * 1992-06-26 1999-08-17 The Procter & Gamble Company Biodegradable polymeric compositions and products thereof
US5703160A (en) 1992-07-15 1997-12-30 Solvay S.A. Biodegradable moulding compositions comprising a starch, a biodegradable polyester, and a salt of a hydroxycarboxylic acid
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5278256A (en) * 1992-09-16 1994-01-11 E. I. Du Pont De Nemours And Company Rapidly degradable poly (hydroxyacid) compositions
GB9223351D0 (en) * 1992-11-06 1992-12-23 Ici Plc Polyesters
GB9223350D0 (en) * 1992-11-06 1992-12-23 Ici Plc Polymer composition
EP0601885B1 (en) 1992-12-11 1998-06-03 Takasago International Corporation Biodegradable optically active polymer of lactones and process for production thereof
JP3263710B2 (ja) * 1992-12-11 2002-03-11 高砂香料工業株式会社 生分解性光学活性ポリマー及びその製造方法
US5443458A (en) * 1992-12-22 1995-08-22 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method of manufacture
US5468253A (en) 1993-01-21 1995-11-21 Ethicon, Inc. Elastomeric medical device
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5412067A (en) * 1993-05-10 1995-05-02 Mitsui Toatsu Chemicals, Inc. Preparation process of polyester
GB9311402D0 (en) * 1993-06-02 1993-07-21 Zeneca Ltd Processing of polyesters
US5874040A (en) * 1993-06-02 1999-02-23 Monsanto Company Processing of polyesters
JP3243334B2 (ja) 1993-06-10 2002-01-07 テルモ株式会社 ヒドロキシアルカノエート重合体組成物
WO1995001167A2 (en) * 1993-06-25 1995-01-12 Alza Corporation Incorporating poly-n-vinyl amide in a transdermal system
US5814599A (en) 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs
WO1995018781A1 (en) * 1994-01-06 1995-07-13 Metabolix, Inc. Methods for synthesizing oligomers containing hydroxy acid units
ZA95627B (en) * 1994-01-28 1995-10-05 Procter & Gamble Biodegradable copolymers and plastic articles comprising biodegradable copolymers
ES2251716T3 (es) * 1994-01-28 2006-05-01 THE PROCTER & GAMBLE COMPANY Copolimeros biodegradables y articulos de plastico que comprenden copolimeros biodegradables de 3-hidroxihexanoato.
US5584885A (en) 1994-04-28 1996-12-17 Seckel; Brooke R. Nerve regeneration chamber
DE69531638T2 (de) * 1994-06-06 2004-06-17 Osiris Therapeutics, Inc. Biomatrix für geweberegenaration
US5629077A (en) * 1994-06-27 1997-05-13 Advanced Cardiovascular Systems, Inc. Biodegradable mesh and film stent
CA2195787A1 (en) * 1994-08-12 1996-02-22 Denise R. Rutherford Poly(.beta.-hydroxyorganoate) pressure sensitive adhesive compositions
US5599852A (en) * 1994-10-18 1997-02-04 Ethicon, Inc. Injectable microdispersions for soft tissue repair and augmentation
AU706434B2 (en) 1994-10-18 1999-06-17 Ethicon Inc. Injectable liquid copolymers for soft tissue repair and augmentation
US5563239A (en) 1994-11-09 1996-10-08 Eastman Chemical Company Composition and process for the production of poly(3-hydroxyalkanoates)
US5814071A (en) 1994-11-10 1998-09-29 Innovasive Devices, Inc. Suture anchor assembly and methods
US5824751A (en) 1995-01-26 1998-10-20 Takasago Koryo Kogyo Kabushiki Kaisha (Takasago International Corporation) Biodegradable high molecular composition
JP3519480B2 (ja) * 1995-02-16 2004-04-12 ユニチカ株式会社 微生物分解性モノフィラメントの製造法
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
US5840331A (en) 1995-06-07 1998-11-24 Arch Development Corporation Use of γ-hydroxybutyrate for the stimulation of sleep-related secretion growth hormone and prolactin
DE19539449A1 (de) * 1995-10-24 1997-04-30 Biotronik Mess & Therapieg Verfahren zur Herstellung intraluminaler Stents aus bioresorbierbarem Polymermaterial
US5842477A (en) 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
US5670161A (en) 1996-05-28 1997-09-23 Healy; Kevin E. Biodegradable stent
US5811272A (en) 1996-07-26 1998-09-22 Massachusetts Institute Of Technology Method for controlling molecular weight of polyhydroxyalkanoates
HUP0001256A3 (en) * 1997-04-03 2002-12-28 Univ Johns Hopkins Med Biodegradable terephthalate polyester-poly(phosphate) polymers, compositions, method for making the same and using them
ATE364709T1 (de) 1997-04-21 2007-07-15 Metabolix Inc Endstellige hydroxyl aufweisende polyhydroxyalkanoate
US6245537B1 (en) 1997-05-12 2001-06-12 Metabolix, Inc. Removing endotoxin with an oxdizing agent from polyhydroxyalkanoates produced by fermentation
US6610764B1 (en) * 1997-05-12 2003-08-26 Metabolix, Inc. Polyhydroxyalkanoate compositions having controlled degradation rates
US6119567A (en) 1997-07-10 2000-09-19 Ktm Industries, Inc. Method and apparatus for producing a shaped article
US5876455A (en) * 1997-07-24 1999-03-02 Harwin; Steven F. Bio-shim
US5990162A (en) 1997-08-29 1999-11-23 Orphan Medical, Inc. Method for treatment of fibromyalgia and chronic fatigue syndrome
US6316262B1 (en) 1997-09-19 2001-11-13 Metabolix, Inc. Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids
AU751082B2 (en) 1997-10-31 2002-08-08 Children's Medical Center Corporation Penile reconstruction
US6626939B1 (en) * 1997-12-18 2003-09-30 Boston Scientific Scimed, Inc. Stent-graft with bioabsorbable structural support
AU751610B2 (en) 1997-12-22 2002-08-22 Tepha, Inc. Polyhydroxyalkanoate compositions having controlled degradation rates
JPH11199514A (ja) 1998-01-13 1999-07-27 Meiji Seika Kaisha Ltd 徐放性製剤組成物
US6056970A (en) * 1998-05-07 2000-05-02 Genzyme Corporation Compositions comprising hemostatic compounds and bioabsorbable polymers
DE69942799D1 (en) 1998-05-22 2010-11-11 Metabolix Inc Polyhydroxyalkanoatbiopolymere
US7662409B2 (en) * 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
JP2002527144A (ja) 1998-10-12 2002-08-27 セリックス， インコーポレイテッド 組織再生のための複合体およびその製造方法
FR2784580B1 (fr) * 1998-10-16 2004-06-25 Biosepra Inc Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
JP2000220032A (ja) * 1999-01-28 2000-08-08 Toray Ind Inc 極細ポリエステルマルチフィラメント糸、混繊糸および織編物
US6656489B1 (en) 1999-02-10 2003-12-02 Isotis N.V. Scaffold for tissue engineering cartilage having outer surface layers of copolymer and ceramic material
AU3722800A (en) 1999-03-04 2000-09-21 Tepha, Inc. Bioabsorbable, biocompatible polymers for tissue engineering
EP1867348B1 (en) * 1999-03-25 2012-05-16 Metabolix, Inc. Medical devices and applications of polyhydroxyalkanoate polymers
US7025980B1 (en) * 1999-09-14 2006-04-11 Tepha, Inc. Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation
EP1130043B1 (en) 2000-02-29 2006-01-25 Canon Kabushiki Kaisha Polyhydroxyalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same
US6867249B2 (en) * 2000-08-18 2005-03-15 Kin Man Amazon Lee Lightweight and porous construction materials containing rubber
WO2002085983A1 (en) * 2001-04-20 2002-10-31 E.I. Du Pont De Nemours And Company Processing of polyhydroxyalkanoates using a nucleant and a plasticizer
US20020168518A1 (en) * 2001-05-10 2002-11-14 The Procter & Gamble Company Fibers comprising starch and polymers
JP4562316B2 (ja) 2001-06-11 2010-10-13 株式会社カネカ 生分解性繊維およびその製造方法
US6770356B2 (en) * 2001-08-07 2004-08-03 The Procter & Gamble Company Fibers and webs capable of high speed solid state deformation
US20050107505A1 (en) * 2002-02-05 2005-05-19 Hosei Shinoda Biodegradable resin composition and molded object thereof
US7094369B2 (en) 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
ES2741964T3 (es) 2002-05-10 2020-02-12 Tepha Inc Polímero bioabsorbible que contiene monómeros de 2-hidroxiácido
US6838492B2 (en) * 2002-06-17 2005-01-04 Scentco, Llc. Scented paints, paint scenting additive mixtures and processes for producing scented paints
DK1638615T3 (en) * 2003-05-08 2015-01-12 Tepha Inc MEDICAL POLYHYDROXYALKANOATE TEXTILES AND FIBERS
US20060263754A1 (en) * 2003-10-07 2006-11-23 Ann Brazil Educational system
US7834092B2 (en) * 2003-12-12 2010-11-16 E. I. Du Pont De Nemours And Company Article comprising poly(hydroxyalkanoic acid)
JP4326932B2 (ja) 2003-12-16 2009-09-09 本田技研工業株式会社 固定子とその製造方法
US20050267516A1 (en) 2004-06-01 2005-12-01 Farzad Soleimani Embolic protection device for the prevention of stroke
ATE473021T1 (de) * 2004-08-03 2010-07-15 Tepha Inc Nichtkräuselnde polyhydroxyalkanoatnähte
US7594928B2 (en) * 2006-05-17 2009-09-29 Boston Scientific Scimed, Inc. Bioabsorbable stents with reinforced filaments
US20090112259A1 (en) * 2007-10-31 2009-04-30 Angiotech Pharmaceuticals, Inc. Recombinant expressed bioadsorbable polyhydroxyalkonate monofilament and multi-filaments self-retaining sutures

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US7641825B2 (en) 2010-01-05
ATE473021T1 (de) 2010-07-15
DK1778305T3 (da) 2010-10-18
US20100093237A1 (en) 2010-04-15
ES2395464T3 (es) 2013-02-12
DE602005022197D1 (de) 2010-08-19
ATE556727T1 (de) 2012-05-15
US8084125B2 (en) 2011-12-27
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