IT1217783B - Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative - Google Patents
Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relativeInfo
- Publication number
- IT1217783B IT1217783B IT20859/88A IT2085988A IT1217783B IT 1217783 B IT1217783 B IT 1217783B IT 20859/88 A IT20859/88 A IT 20859/88A IT 2085988 A IT2085988 A IT 2085988A IT 1217783 B IT1217783 B IT 1217783B
- Authority
- IT
- Italy
- Prior art keywords
- salo
- dell
- butyric
- alcoholic
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20859/88A IT1217783B (it) | 1988-06-03 | 1988-06-03 | Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative |
ES89109712T ES2075011T3 (es) | 1988-06-03 | 1989-05-30 | Uso de sales del acido gamma-hidroxibutirico para preparar composiciones farmaceuticas para uso en el tratamiento del alcoholismo, y las composiciones obtenidas. |
ZA894128A ZA894128B (en) | 1988-06-03 | 1989-05-30 | Use of gamma-hydroxybutryic acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism,and the compositions obtained |
EP89109712A EP0344704B1 (en) | 1988-06-03 | 1989-05-30 | Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained |
AT89109712T ATE126433T1 (de) | 1988-06-03 | 1989-05-30 | Verwendung von gamma-hydroxy-buttersäuresalzen zur herstellung von pharmazeutischen zusammensetzungen zur verwendung bei der behandlung von alkoholismus und die hergestellten zusammensetzungen. |
DE68923819T DE68923819T2 (de) | 1988-06-03 | 1989-05-30 | Verwendung von gamma-Hydroxy-Buttersäuresalzen zur Herstellung von pharmazeutischen Zusammensetzungen zur Verwendung bei der Behandlung von Alkoholismus und die hergestellten Zusammensetzungen. |
AU35904/89A AU633002B2 (en) | 1988-06-03 | 1989-06-01 | Use of gamma-hydroxybutyric acid salts in the treatment of alcoholism and pharmaceutical compositions thereof |
PT90732A PT90732B (pt) | 1988-06-03 | 1989-06-02 | Processo para a preparacao de composicoes farmaceuticas adequadas para serem empregues na terapia do alcoolismo, a base de sais do acido gama-hidroxibutirico |
DK198902723A DK174017B1 (da) | 1988-06-03 | 1989-06-02 | Anvendelse af gamma-hydroxysmørsyresalte til fremstilling af farmaceutiske præparater til behandling af alkoholisme |
NO89892270A NO892270L (no) | 1988-06-03 | 1989-06-02 | Fremgangsmaate for fremstilling av preparater for anvendelse ved behandlingen av alkoholisme. |
CA000601648A CA1330423C (en) | 1988-06-03 | 1989-06-02 | Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained |
NZ229399A NZ229399A (en) | 1988-06-03 | 1989-06-02 | Pharmaceutical compositions comprising gamma-hydroxy-butyric acid salts |
AR89314068A AR241512A1 (es) | 1988-06-03 | 1989-06-02 | Un procedimiento para la preparacion de composiciones utiles para la terapia del alcolismo. |
US07/361,490 US4983632A (en) | 1988-06-03 | 1989-06-02 | Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained |
FI892718A FI892718A (fi) | 1988-06-03 | 1989-06-02 | Foerfarande foer framstaellning av farmaceutiska kompositioner foer anvaendning vid behandling av alkoholism. |
IE178589A IE68685B1 (en) | 1988-06-03 | 1989-06-12 | Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism and the compositions obtained |
GR950403119T GR3018009T3 (en) | 1988-06-03 | 1995-11-08 | Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20859/88A IT1217783B (it) | 1988-06-03 | 1988-06-03 | Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8820859A0 IT8820859A0 (it) | 1988-06-03 |
IT1217783B true IT1217783B (it) | 1990-03-30 |
Family
ID=11173141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT20859/88A IT1217783B (it) | 1988-06-03 | 1988-06-03 | Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative |
Country Status (16)
Country | Link |
---|---|
US (1) | US4983632A (it) |
EP (1) | EP0344704B1 (it) |
AR (1) | AR241512A1 (it) |
AT (1) | ATE126433T1 (it) |
AU (1) | AU633002B2 (it) |
CA (1) | CA1330423C (it) |
DE (1) | DE68923819T2 (it) |
DK (1) | DK174017B1 (it) |
ES (1) | ES2075011T3 (it) |
FI (1) | FI892718A (it) |
GR (1) | GR3018009T3 (it) |
IT (1) | IT1217783B (it) |
NO (1) | NO892270L (it) |
NZ (1) | NZ229399A (it) |
PT (1) | PT90732B (it) |
ZA (1) | ZA894128B (it) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5153219A (en) * | 1991-04-22 | 1992-10-06 | Morris D. Faiman | Thiocarbamate sulfoxide composition for deterring ethanol ingestion |
IT1248588B (it) * | 1991-06-28 | 1995-01-19 | Gaetano Crepaldi | Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari. |
WO1993002682A1 (en) * | 1991-08-06 | 1993-02-18 | Labco Pharmaceuticals, Inc. | Method and compositions for reducing craving for alcohol and stimulants |
US5366990A (en) * | 1991-11-14 | 1994-11-22 | Reid Larry D | Method for treating alcohol abuse and alcoholism |
IT1261432B (it) * | 1993-03-26 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Uso di acil l- carnitina gammaidrossibutirrato per il trattamento dell'alcolismo. |
IT1261485B (it) * | 1993-06-24 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Uso di acil l-carnitine gamma-idrossibutirrato per il trattamento di tossicodipendenze. |
IT1266565B1 (it) * | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
IT1283782B1 (it) * | 1996-08-09 | 1998-04-30 | Ct Lab Farm Srl | Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo |
EP1316309A1 (en) * | 1998-12-23 | 2003-06-04 | Orphan Medical Inc. | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy |
JP4374441B2 (ja) | 1998-12-23 | 2009-12-02 | ジェイピーアイ コマーシャル,リミティド ライアビリティ カンパニー | 睡眠発作治療のための、ガンマ−ヒドロキシ酪酸塩の微生物的に安全で安定な液剤 |
JP4723143B2 (ja) | 1999-09-14 | 2011-07-13 | テファ, インコーポレイテッド | γ−ヒドロキシブチレートを含むポリマーおよびオリゴマーの治療的用途 |
ITMI20020754A1 (it) * | 2002-04-09 | 2003-10-09 | Aboca S P A | Composizioni effervescenti contenenti succhi di frutta essicati |
EP2860292B1 (en) | 2003-05-08 | 2020-07-22 | Tepha, Inc. | Polyhydroxyalkanoate medical textiles and fibers |
EP1778305B1 (en) | 2004-08-03 | 2010-07-07 | Tepha, Inc. | Non-curling polyhydroxyalkanoate sutures |
US7838556B2 (en) * | 2006-02-21 | 2010-11-23 | University Of Maryland, Baltimore | Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands |
US20100144885A1 (en) * | 2006-09-29 | 2010-06-10 | The Board Of Trustees Of The University Of Illinois | Histone acetyl transferase activators and histone deacetylase inhibitors in the treatment of alcoholism |
US7943683B2 (en) | 2006-12-01 | 2011-05-17 | Tepha, Inc. | Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers |
US8778398B2 (en) | 2008-11-04 | 2014-07-15 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
US8771735B2 (en) | 2008-11-04 | 2014-07-08 | Jazz Pharmaceuticals, Inc. | Immediate release dosage forms of sodium oxybate |
FR2938431B1 (fr) | 2008-11-14 | 2013-12-20 | Debregeas Et Associes Pharma | Nouvelle composition a base d'acide gamma-hydroxybutyrique |
FR2949062B1 (fr) | 2009-08-12 | 2011-09-02 | Debregeas Et Associes Pharma | Nouvelles formulations pharmaceutiques contre le mesusage des medicaments |
FR2949061B1 (fr) | 2009-08-12 | 2013-04-19 | Debregeas Et Associes Pharma | Microgranules flottants |
BR112012024019B1 (pt) | 2010-03-24 | 2021-10-19 | Jazz Phamaceuticals, Inc | Forma de dosagem de liberação controlada para administração oral |
CA2798178C (en) * | 2010-05-04 | 2017-06-13 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
US8591922B1 (en) | 2012-12-14 | 2013-11-26 | Jazz Pharmacuticals, Inc. | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
US9050302B2 (en) | 2013-03-01 | 2015-06-09 | Jazz Pharmaceuticals Ireland Limited | Method of administration of gamma hydroxybutyrate with monocarboxylate transporters |
US10500303B2 (en) | 2014-08-15 | 2019-12-10 | Tepha, Inc. | Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof |
US10626521B2 (en) | 2014-12-11 | 2020-04-21 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
US9555155B2 (en) | 2014-12-11 | 2017-01-31 | Tepha, Inc. | Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof |
US10398662B1 (en) | 2015-02-18 | 2019-09-03 | Jazz Pharma Ireland Limited | GHB formulation and method for its manufacture |
UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US20180263936A1 (en) | 2017-03-17 | 2018-09-20 | Jazz Pharmaceuticals Ireland Limited | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
AU2019383389A1 (en) | 2018-11-19 | 2021-05-06 | Jazz Pharmaceuticals Ireland Limited | Alcohol-resistant drug formulations |
US11400065B2 (en) | 2019-03-01 | 2022-08-02 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0044801B1 (de) * | 1980-07-17 | 1984-02-15 | Josef Dr. Klosa | Nichthygroskopische Salze der 4-Hydroxybuttersäure, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Mittel |
-
1988
- 1988-06-03 IT IT20859/88A patent/IT1217783B/it active
-
1989
- 1989-05-30 AT AT89109712T patent/ATE126433T1/de not_active IP Right Cessation
- 1989-05-30 ZA ZA894128A patent/ZA894128B/xx unknown
- 1989-05-30 ES ES89109712T patent/ES2075011T3/es not_active Expired - Lifetime
- 1989-05-30 DE DE68923819T patent/DE68923819T2/de not_active Expired - Lifetime
- 1989-05-30 EP EP89109712A patent/EP0344704B1/en not_active Expired - Lifetime
- 1989-06-01 AU AU35904/89A patent/AU633002B2/en not_active Expired
- 1989-06-02 PT PT90732A patent/PT90732B/pt not_active IP Right Cessation
- 1989-06-02 AR AR89314068A patent/AR241512A1/es active
- 1989-06-02 FI FI892718A patent/FI892718A/fi not_active Application Discontinuation
- 1989-06-02 NZ NZ229399A patent/NZ229399A/en unknown
- 1989-06-02 CA CA000601648A patent/CA1330423C/en not_active Expired - Lifetime
- 1989-06-02 NO NO89892270A patent/NO892270L/no unknown
- 1989-06-02 DK DK198902723A patent/DK174017B1/da not_active IP Right Cessation
- 1989-06-02 US US07/361,490 patent/US4983632A/en not_active Expired - Lifetime
-
1995
- 1995-11-08 GR GR950403119T patent/GR3018009T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT90732A (pt) | 1989-12-29 |
AU633002B2 (en) | 1993-01-21 |
US4983632A (en) | 1991-01-08 |
NO892270D0 (no) | 1989-06-02 |
GR3018009T3 (en) | 1996-02-29 |
IT8820859A0 (it) | 1988-06-03 |
EP0344704B1 (en) | 1995-08-16 |
DK272389A (da) | 1989-12-04 |
DE68923819T2 (de) | 1996-01-18 |
AU3590489A (en) | 1989-12-07 |
AR241512A1 (es) | 1992-08-31 |
ES2075011T3 (es) | 1995-10-01 |
NO892270L (no) | 1989-12-04 |
NZ229399A (en) | 1997-02-24 |
CA1330423C (en) | 1994-06-28 |
ZA894128B (en) | 1990-03-28 |
PT90732B (pt) | 1994-10-31 |
DK272389D0 (da) | 1989-06-02 |
FI892718A0 (fi) | 1989-06-02 |
EP0344704A1 (en) | 1989-12-06 |
FI892718A (fi) | 1989-12-04 |
DK174017B1 (da) | 2002-04-15 |
ATE126433T1 (de) | 1995-09-15 |
DE68923819D1 (de) | 1995-09-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT1217783B (it) | Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative | |
EP0232849A3 (en) | Pyrrolidineamide derivative of acylamino acid, pharmaceutical composition and use | |
IT1221079B (it) | Derivati di anilina terapeuticamente attivi,procedimento per la loro preparazione e composizioni farmaceutiche che il contengono | |
AU6328586A (en) | Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade | |
AU1283588A (en) | New pharmaceutical compositions in the form of beadlets and method | |
IT8468281A0 (it) | Proglumide e composizioni farmaceutiche che la contengono per l impiego nella terapia di affezioni neoplastiche | |
IT8720389A0 (it) | Esteri retinoici di antibiotici, loro procedimento di preparazione e composizioni farmaceutiche e cosmetiche che li contengono. | |
IT8619284A0 (it) | Composizione per la preparazione estemporanea di formulazioni per applicazioni topiche per uso farmaceutico e cosmetico. | |
IT8920358A0 (it) | Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale. | |
IT1204571B (it) | Esteri di 1,4:3,6-dianidrosorbitolo-2-mononitrato e 5-mononitrato,loro procedimento di preparazione e loro composizioni farmaceutiche | |
IL109093A0 (en) | Phenylglycinamides of heterocyclically substituted phenylacetic acid derivatives, their preparation and pharmaceutical compositions containing them | |
IT8148166A0 (it) | Ne e loro uso terapeutico esteri di mercaptoacil-carnitine procedimento per la loro preparazio | |
IT1186754B (it) | Composizioni farmaceutiche e cosmetiche contenenti come ingrediente attivo diidrossi-1,8 fenil-10 antrone-9,e procedimento di preparazione dell'ingrediente attivo | |
IT8103423A0 (it) | Derivati di alcandioli conattivita' ipolipidemizzante, metodi per la loro preparazione e composizioni farmaceutiche che licontengono | |
IT7949403A0 (it) | Imminotiazolil ureido cefalosporine composizioni farmaceutiche che le contengono e procedimento per la loro preparazione | |
IT1164027B (it) | Procedimento per la preparazione di cloridrati di amminoacidi e bicloridrati di diamminoacidi | |
IT8622877A0 (it) | Esteri dell'azoniaspironortropanolo, procedimento per la loro preparazione, mezzi farmaceutici che li contengono e impiego di esteri dell'azoniaspironortropanolo come spasmolitico, asmaterapeutico e broncolitico. | |
IT1214729B (it) | Derivati di acido tiofenacetico,procedimento per la loro preparazione, composizioni farmaceutiche che licontengono e loro impiego come medicamenti | |
IT8520515A0 (it) | Composizioni di farmaci eprocedimento per la loro preparazione. | |
IT8321704A0 (it) | Derivato idrosolubile del1-(2-idrossietil)-2-metil-5-nitroimidazolo ad attivita' terapeutica, procedimento per la sua preparazione e relative composizioni farmaceutiche | |
DE3564806D1 (en) | Benzoylpropionic acid derivatives, their use and pharmaceutical compositions | |
IT1227158B (it) | Esteri dell'acido tiamorfolinone carbossilico e di suoi derivati, loro procedimento di preparazione e loro impiego nel settore cosmetico e nel settore dermo farmaceutico. | |
ITMI913398A1 (it) | Derivati dell'eserolina ad attivita' anticolinesterasica procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. | |
IT8521662A0 (it) | Derivato dell'acido chinolin-3-carbossilico, procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono. | |
IT8419262A0 (it) | Esteri della l-carnitina e della l-acetilcarnitina, procedimento per la loro preparazione e composizioni farmaceutiche che licontengono. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970630 |