IT8820859A0 - Impiego di sali dell'acido gamma idrossi butirrico per lapreparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell'alcolismo e composizioni relative. - Google Patents

Impiego di sali dell'acido gamma idrossi butirrico per lapreparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell'alcolismo e composizioni relative.

Info

Publication number
IT8820859A0
IT8820859A0 IT8820859A IT2085988A IT8820859A0 IT 8820859 A0 IT8820859 A0 IT 8820859A0 IT 8820859 A IT8820859 A IT 8820859A IT 2085988 A IT2085988 A IT 2085988A IT 8820859 A0 IT8820859 A0 IT 8820859A0
Authority
IT
Italy
Prior art keywords
alcoholism
therapy
preparation
butyric acid
acid salts
Prior art date
Application number
IT8820859A
Other languages
English (en)
Other versions
IT1217783B (it
Inventor
G L Gessa
F Fadda
C Mormile
Original Assignee
Farmaceutico Ct S R L Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutico Ct S R L Lab filed Critical Farmaceutico Ct S R L Lab
Publication of IT8820859A0 publication Critical patent/IT8820859A0/it
Priority to IT20859/88A priority Critical patent/IT1217783B/it
Priority to DE68923819T priority patent/DE68923819T2/de
Priority to ZA894128A priority patent/ZA894128B/xx
Priority to EP89109712A priority patent/EP0344704B1/en
Priority to ES89109712T priority patent/ES2075011T3/es
Priority to AT89109712T priority patent/ATE126433T1/de
Priority to AU35904/89A priority patent/AU633002B2/en
Priority to US07/361,490 priority patent/US4983632A/en
Priority to NO89892270A priority patent/NO892270L/no
Priority to NZ229399A priority patent/NZ229399A/en
Priority to CA000601648A priority patent/CA1330423C/en
Priority to PT90732A priority patent/PT90732B/pt
Priority to FI892718A priority patent/FI892718A/fi
Priority to DK198902723A priority patent/DK174017B1/da
Priority to AR89314068A priority patent/AR241512A1/es
Priority to IE178589A priority patent/IE68685B1/en
Application granted granted Critical
Publication of IT1217783B publication Critical patent/IT1217783B/it
Priority to GR950403119T priority patent/GR3018009T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT20859/88A 1988-06-03 1988-06-03 Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative IT1217783B (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IT20859/88A IT1217783B (it) 1988-06-03 1988-06-03 Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative
DE68923819T DE68923819T2 (de) 1988-06-03 1989-05-30 Verwendung von gamma-Hydroxy-Buttersäuresalzen zur Herstellung von pharmazeutischen Zusammensetzungen zur Verwendung bei der Behandlung von Alkoholismus und die hergestellten Zusammensetzungen.
ZA894128A ZA894128B (en) 1988-06-03 1989-05-30 Use of gamma-hydroxybutryic acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism,and the compositions obtained
EP89109712A EP0344704B1 (en) 1988-06-03 1989-05-30 Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained
ES89109712T ES2075011T3 (es) 1988-06-03 1989-05-30 Uso de sales del acido gamma-hidroxibutirico para preparar composiciones farmaceuticas para uso en el tratamiento del alcoholismo, y las composiciones obtenidas.
AT89109712T ATE126433T1 (de) 1988-06-03 1989-05-30 Verwendung von gamma-hydroxy-buttersäuresalzen zur herstellung von pharmazeutischen zusammensetzungen zur verwendung bei der behandlung von alkoholismus und die hergestellten zusammensetzungen.
AU35904/89A AU633002B2 (en) 1988-06-03 1989-06-01 Use of gamma-hydroxybutyric acid salts in the treatment of alcoholism and pharmaceutical compositions thereof
NO89892270A NO892270L (no) 1988-06-03 1989-06-02 Fremgangsmaate for fremstilling av preparater for anvendelse ved behandlingen av alkoholisme.
US07/361,490 US4983632A (en) 1988-06-03 1989-06-02 Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained
NZ229399A NZ229399A (en) 1988-06-03 1989-06-02 Pharmaceutical compositions comprising gamma-hydroxy-butyric acid salts
CA000601648A CA1330423C (en) 1988-06-03 1989-06-02 Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained
PT90732A PT90732B (pt) 1988-06-03 1989-06-02 Processo para a preparacao de composicoes farmaceuticas adequadas para serem empregues na terapia do alcoolismo, a base de sais do acido gama-hidroxibutirico
FI892718A FI892718A (fi) 1988-06-03 1989-06-02 Foerfarande foer framstaellning av farmaceutiska kompositioner foer anvaendning vid behandling av alkoholism.
DK198902723A DK174017B1 (da) 1988-06-03 1989-06-02 Anvendelse af gamma-hydroxysmørsyresalte til fremstilling af farmaceutiske præparater til behandling af alkoholisme
AR89314068A AR241512A1 (es) 1988-06-03 1989-06-02 Un procedimiento para la preparacion de composiciones utiles para la terapia del alcolismo.
IE178589A IE68685B1 (en) 1988-06-03 1989-06-12 Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism and the compositions obtained
GR950403119T GR3018009T3 (en) 1988-06-03 1995-11-08 Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20859/88A IT1217783B (it) 1988-06-03 1988-06-03 Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative

Publications (2)

Publication Number Publication Date
IT8820859A0 true IT8820859A0 (it) 1988-06-03
IT1217783B IT1217783B (it) 1990-03-30

Family

ID=11173141

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20859/88A IT1217783B (it) 1988-06-03 1988-06-03 Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative

Country Status (16)

Country Link
US (1) US4983632A (it)
EP (1) EP0344704B1 (it)
AR (1) AR241512A1 (it)
AT (1) ATE126433T1 (it)
AU (1) AU633002B2 (it)
CA (1) CA1330423C (it)
DE (1) DE68923819T2 (it)
DK (1) DK174017B1 (it)
ES (1) ES2075011T3 (it)
FI (1) FI892718A (it)
GR (1) GR3018009T3 (it)
IT (1) IT1217783B (it)
NO (1) NO892270L (it)
NZ (1) NZ229399A (it)
PT (1) PT90732B (it)
ZA (1) ZA894128B (it)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153219A (en) * 1991-04-22 1992-10-06 Morris D. Faiman Thiocarbamate sulfoxide composition for deterring ethanol ingestion
IT1248588B (it) * 1991-06-28 1995-01-19 Gaetano Crepaldi Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari.
WO1993002682A1 (en) * 1991-08-06 1993-02-18 Labco Pharmaceuticals, Inc. Method and compositions for reducing craving for alcohol and stimulants
US5366990A (en) * 1991-11-14 1994-11-22 Reid Larry D Method for treating alcohol abuse and alcoholism
IT1261432B (it) * 1993-03-26 1996-05-23 Sigma Tau Ind Farmaceuti Uso di acil l- carnitina gammaidrossibutirrato per il trattamento dell'alcolismo.
IT1261485B (it) * 1993-06-24 1996-05-23 Sigma Tau Ind Farmaceuti Uso di acil l-carnitine gamma-idrossibutirrato per il trattamento di tossicodipendenze.
IT1266565B1 (it) * 1993-07-22 1997-01-09 Ct Lab Farm Srl Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico.
IT1283782B1 (it) * 1996-08-09 1998-04-30 Ct Lab Farm Srl Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo
EP1140061B1 (en) * 1998-12-23 2003-05-02 Orphan Medical Inc. Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
EP1316309A1 (en) * 1998-12-23 2003-06-04 Orphan Medical Inc. Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
JP4723143B2 (ja) 1999-09-14 2011-07-13 テファ， インコーポレイテッド γ−ヒドロキシブチレートを含むポリマーおよびオリゴマーの治療的用途
ITMI20020754A1 (it) * 2002-04-09 2003-10-09 Aboca S P A Composizioni effervescenti contenenti succhi di frutta essicati
JP2007525601A (ja) 2003-05-08 2007-09-06 テファ， インコーポレイテッド ポリヒドロキシアルカノエート医療用織物および医療用繊維
DK1778305T3 (da) 2004-08-03 2010-10-18 Tepha Inc Ikke-krøllende polyhydroxyalkanoatsuturer
US7838556B2 (en) * 2006-02-21 2010-11-23 University Of Maryland, Baltimore Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands
EP2073812A4 (en) * 2006-09-29 2012-08-08 Univ Illinois ACTIVISTS OF HISTONE ACETYLTRANSFERASE AND INHIBITORS OF HISTONE DEACETYLASE IN THE TREATMENT OF ALCOHOLISM
US7943683B2 (en) 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
US8778398B2 (en) 2008-11-04 2014-07-15 Jazz Pharmaceuticals, Inc. Immediate release formulations and dosage forms of gamma-hydroxybutyrate
US8771735B2 (en) 2008-11-04 2014-07-08 Jazz Pharmaceuticals, Inc. Immediate release dosage forms of sodium oxybate
FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
US20120076865A1 (en) 2010-03-24 2012-03-29 Jazz Pharmaceuticals, Inc. Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances
EP2566462B1 (en) * 2010-05-04 2020-07-08 Jazz Pharmaceuticals Inc. Immediate release formulations and dosage forms of gamma-hydroxybutyrate
US8591922B1 (en) 2012-12-14 2013-11-26 Jazz Pharmacuticals, Inc. Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
US9050302B2 (en) 2013-03-01 2015-06-09 Jazz Pharmaceuticals Ireland Limited Method of administration of gamma hydroxybutyrate with monocarboxylate transporters
CA2958747C (en) 2014-08-15 2022-08-16 Tepha, Inc. Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof
WO2016094669A1 (en) 2014-12-11 2016-06-16 Tepha, Inc. Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
US10398662B1 (en) 2015-02-18 2019-09-03 Jazz Pharma Ireland Limited GHB formulation and method for its manufacture
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602513B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US20180263936A1 (en) 2017-03-17 2018-09-20 Jazz Pharmaceuticals Ireland Limited Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
AU2019383389A1 (en) 2018-11-19 2021-05-06 Jazz Pharmaceuticals Ireland Limited Alcohol-resistant drug formulations
CA3127871A1 (en) 2019-03-01 2020-09-10 Flamel Ireland Limited Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044801B1 (de) * 1980-07-17 1984-02-15 Josef Dr. Klosa Nichthygroskopische Salze der 4-Hydroxybuttersäure, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Mittel

Also Published As

Publication number Publication date
US4983632A (en) 1991-01-08
PT90732A (pt) 1989-12-29
DK272389D0 (da) 1989-06-02
AR241512A1 (es) 1992-08-31
DK272389A (da) 1989-12-04
IT1217783B (it) 1990-03-30
DE68923819D1 (de) 1995-09-21
ATE126433T1 (de) 1995-09-15
PT90732B (pt) 1994-10-31
DE68923819T2 (de) 1996-01-18
AU3590489A (en) 1989-12-07
EP0344704A1 (en) 1989-12-06
DK174017B1 (da) 2002-04-15
ES2075011T3 (es) 1995-10-01
AU633002B2 (en) 1993-01-21
GR3018009T3 (en) 1996-02-29
FI892718A (fi) 1989-12-04
NZ229399A (en) 1997-02-24
ZA894128B (en) 1990-03-28
NO892270D0 (no) 1989-06-02
FI892718A0 (fi) 1989-06-02
CA1330423C (en) 1994-06-28
NO892270L (no) 1989-12-04
EP0344704B1 (en) 1995-08-16

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970630