CY1108505T1 - Σκευασματα κολικου καθαρισμου - Google Patents
Σκευασματα κολικου καθαρισμουInfo
- Publication number
- CY1108505T1 CY1108505T1 CY20081101293T CY081101293T CY1108505T1 CY 1108505 T1 CY1108505 T1 CY 1108505T1 CY 20081101293 T CY20081101293 T CY 20081101293T CY 081101293 T CY081101293 T CY 081101293T CY 1108505 T1 CY1108505 T1 CY 1108505T1
- Authority
- CY
- Cyprus
- Prior art keywords
- ascorbic acid
- sodium phosphate
- sodium
- based formulations
- better
- Prior art date
Links
- 238000004140 cleaning Methods 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 238000009472 formulation Methods 0.000 abstract 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 2
- 235000010323 ascorbic acid Nutrition 0.000 abstract 2
- 239000011668 ascorbic acid Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 239000001488 sodium phosphate Substances 0.000 abstract 2
- 229910000162 sodium phosphate Inorganic materials 0.000 abstract 2
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 abstract 2
- 239000004097 EU approved flavor enhancer Substances 0.000 abstract 1
- 150000000996 L-ascorbic acids Chemical class 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 abstract 1
- 229910052936 alkali metal sulfate Inorganic materials 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000002052 colonoscopy Methods 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
- 235000019264 food flavour enhancer Nutrition 0.000 abstract 1
- 239000001103 potassium chloride Substances 0.000 abstract 1
- 235000011164 potassium chloride Nutrition 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 235000002639 sodium chloride Nutrition 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Detergent Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Ένα σκεύασμα που περιέχει, ανά λίτρο υδατικού διαλύματος, από 30 ως 350 g πολυαιθυλενογλυκόλης, από 3 ως 20 g ενός συστατικού ασκορβικού οξέος που επιλέγεται από την ομάδα που περιλαμβάνει ασκορβικό οξύ, ένα άλας ασκορβικού οξέος, ή ένα μίγμα αυτών, ένα θειικό άλας αλκαλιμετάλλου ή αλκαλικής γαίας, κατά προτίμηση 1 ως 15 g αυτού, και προαιρετικώς έναν ή περισσότερους ηλεκτρολύτες που επιλέγονται από χλωριούχο νάτριο, χλωριούχο κάλιο, και όξινο ανθρακικό νάτριο, και κατά προτίμηση επίσης βελτιωτικά γεύσης, είναι αποτελεσματικό για τον καθαρισμό του εντέρου κατά την προετοιμασία για ενδοσκοπική εξέταση, και ιδιαίτερα κολονοσκόπηση. Είναι ασφαλέστερο από συμβατικά σκευάσματα καθαρισμού του εντέρου που βασίζονται σε φωσφορικό νάτριο, και συνεπώς μπορεί να χρησιμοποιηθεί σε ασθενείς που κινδυνεύουν με σκευάσματα που βασίζονται σε φωσφορικό νάτριο, και είναι καλύτερα ανεκτό από συμβατικά σκευάσματα που βασίζονται σε PEG, πράγμα που οδηγεί σε καλύτερη συμμόρφωση ασθενών και καθιστά δυνατή την αποτελεσματική χρήση σε εξωτερικούς ασθενείς.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0224909.2A GB0224909D0 (en) | 2002-10-25 | 2002-10-25 | Colon cleansing compositions |
EP03758361A EP1567193B1 (en) | 2002-10-25 | 2003-10-24 | Colon cleansing compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108505T1 true CY1108505T1 (el) | 2014-04-09 |
Family
ID=9946609
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081101293T CY1108505T1 (el) | 2002-10-25 | 2008-11-12 | Σκευασματα κολικου καθαρισμου |
CY20131100308T CY1113933T1 (el) | 2002-10-25 | 2013-04-12 | Σκευασματα κολικου καθαρισμου |
CY20191100829T CY1121977T1 (el) | 2002-10-25 | 2019-08-05 | Συνθεσεις καθαρισμου του κολον |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20131100308T CY1113933T1 (el) | 2002-10-25 | 2013-04-12 | Σκευασματα κολικου καθαρισμου |
CY20191100829T CY1121977T1 (el) | 2002-10-25 | 2019-08-05 | Συνθεσεις καθαρισμου του κολον |
Country Status (23)
Country | Link |
---|---|
US (8) | US7169381B2 (el) |
EP (3) | EP2014304B9 (el) |
JP (3) | JP4131266B2 (el) |
CN (2) | CN101897721B (el) |
AT (1) | ATE404223T1 (el) |
AU (3) | AU2003274377B2 (el) |
CA (2) | CA2502103C (el) |
CY (3) | CY1108505T1 (el) |
DE (4) | DE20321510U1 (el) |
DK (3) | DK2014304T3 (el) |
ES (3) | ES2739387T3 (el) |
GB (1) | GB0224909D0 (el) |
HK (2) | HK1077196A1 (el) |
HU (1) | HUE045881T2 (el) |
LT (1) | LT2314319T (el) |
MX (1) | MXPA05004347A (el) |
PL (2) | PL216059B1 (el) |
PT (3) | PT1567193E (el) |
RU (3) | RU2519562C9 (el) |
SI (3) | SI1567193T1 (el) |
TR (1) | TR201909741T4 (el) |
WO (1) | WO2004037292A1 (el) |
ZA (1) | ZA200503247B (el) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0224909D0 (en) * | 2002-10-25 | 2002-12-04 | Norgine Europe Bv | Colon cleansing compositions |
WO2005049049A1 (en) * | 2003-11-17 | 2005-06-02 | Braintree Laboratories, Inc. | Therapeutic peg solution concentrate |
JP2005187448A (ja) * | 2004-04-02 | 2005-07-14 | Ajinomoto Co Inc | 腸管洗浄用組成物 |
BRPI0510004A (pt) * | 2004-04-20 | 2007-09-18 | Univ Chicago | artigo de manufatura, métodos para administrar uma composição terapêutica a um epitélio de um indivìduo, para tratar uma condição mediada por micróbio de um epitélio de um indivìduo, para melhorar um sintoma de uma condição e para prevenir uma condição, e, uso de composto tipo peg pma |
US20060051428A1 (en) * | 2004-09-03 | 2006-03-09 | Nelson Ayala | Aspartame and citrate flavored phosphate salt laxative |
GB2471037A (en) * | 2005-10-07 | 2010-12-15 | Cb Fleet Co Inc | Bowel cleansing composition comprising sweeteners |
US20070082061A1 (en) * | 2005-10-07 | 2007-04-12 | Nelson Ayala | Reduction of saltiness with sweeteners |
ES2278537B1 (es) * | 2006-01-30 | 2008-09-16 | Laboratorios Casen-Fleet, S.L. | Procedimiento de fabricacion de una solucion a base de polietilenglicol con electrolitos, producto obtenido y uso. |
US7985429B2 (en) | 2006-03-03 | 2011-07-26 | C. B. Fleet Company, Inc. | Flavored colonic cleansing system |
CN101804068B (zh) * | 2006-03-06 | 2012-05-02 | 桑苏君 | 聚乙二醇-电解质口服溶液 |
CN1850112B (zh) * | 2006-03-06 | 2011-06-29 | 北京圣永制药有限公司 | 聚乙二醇-电解质口服溶液 |
GB0608433D0 (en) * | 2006-04-28 | 2006-06-07 | Obrist Closures Switzerland | Closure with RFID device |
CN100389779C (zh) * | 2006-07-07 | 2008-05-28 | 北京昭衍博纳新药研究有限公司 | 一种用于肠道清洁的药物组合物 |
US7998510B2 (en) * | 2006-08-17 | 2011-08-16 | C. B. Fleet Company, Inc. | Low dose colonic cleansing system |
US20090053304A1 (en) * | 2007-08-23 | 2009-02-26 | Jinling Chen | Composition and method of producing a taste masking formulation of laxatives for bowel cleaning preparation prior to colonoscopy |
US20100297264A1 (en) * | 2007-10-17 | 2010-11-25 | Thomas Jefferson University | Bowel purgative and uses thereof |
ES2509892T3 (es) * | 2008-05-07 | 2014-10-20 | Salix Pharmaceuticals, Ltd. | Administración de un agente para limpieza del intestino y antibiótico para el tratamiento de enfermedad intestinal |
US20100178360A1 (en) * | 2009-01-13 | 2010-07-15 | Universite Libre De Bruxelles | Nutritive composition |
DK2421373T3 (da) * | 2009-04-21 | 2019-12-16 | Dale R Bachwich | Tarmrensningssystem |
GB0912487D0 (en) * | 2009-07-17 | 2009-08-26 | Norgine Bv | Improvements in and relating to colon cleansing compositions |
IT1404366B1 (it) | 2009-07-17 | 2013-11-22 | Norgine Bv | Composizioni perfezionate per la pulizia del colon |
AU2011101324B4 (en) * | 2009-07-17 | 2012-01-19 | Norgine Bv | Improvements in and relating to colon cleansing compositions |
GB0913295D0 (en) * | 2009-07-30 | 2009-09-02 | Norgine Bv | Improvements in and relating to pharmaceutical compositions |
ES2409842T3 (es) | 2009-11-02 | 2013-06-28 | Promefarm S.R.L. | Composiciones para la limpieza intestinal y uso de las mismas |
CA2792647A1 (en) * | 2010-03-10 | 2011-09-15 | Nogra Pharma Limited | Compositions for colon lavage and methods of making and using same |
EP2564875A4 (en) | 2010-04-30 | 2016-03-30 | Ajinomoto Kk | LIQUID PREPARATION FOR ORAL ADMINISTRATION THAT CAN BE USED IN CT COLONOGRAPHY, AND COMPOSITION FOR DIGESTIVE TRACT IMAGING |
CN102232969B (zh) * | 2010-05-07 | 2012-12-19 | 重庆健能医药开发有限公司 | 一种磷酸钠盐组合物 |
ES2951828T3 (es) | 2010-09-23 | 2023-10-25 | Leading Biosciences Inc | Administración de inhibidores de serina proteasa al estómago |
JP5910501B2 (ja) | 2010-10-08 | 2016-04-27 | 味の素株式会社 | Ctコロノグラフィに用いられる経口投与用液剤及び消化管造影用組成物 |
JP5870119B2 (ja) | 2011-01-28 | 2016-02-24 | ブレインツリー ラボラトリーズ、インク. | 腸洗浄のための、方法、組成物、およびパッケージ |
EA201300864A1 (ru) | 2011-01-31 | 2013-12-30 | Адзиномото Ко., Инк. | Многокамерный контейнер |
GB201103942D0 (en) * | 2011-03-08 | 2011-04-20 | Norgine Bv | Compositions |
TWI535461B (zh) * | 2011-03-11 | 2016-06-01 | 諾金私人有限公司 | 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法 |
JP5708141B2 (ja) * | 2011-03-30 | 2015-04-30 | 味の素株式会社 | 経口投与用液剤を調製するための経口投与用製剤 |
CN108904439A (zh) * | 2011-12-07 | 2018-11-30 | Msm创新有限公司 | 味道修饰物质用于修饰胃肠道准备组合物味道的用途 |
US20190314450A1 (en) * | 2011-12-07 | 2019-10-17 | Msm Innovations, Inc. | Method and kit for bowel preparation |
KR101210831B1 (ko) | 2012-02-10 | 2012-12-11 | 주식회사태준제약 | 폴리에틸렌글리콜과 비타민 씨를 함유하는 장관 하제 조성물 |
CN103520202B (zh) * | 2012-07-02 | 2015-09-02 | 舒泰神(北京)生物制药股份有限公司 | 用于通便和清肠的药物组合物 |
CN109260455A (zh) * | 2012-08-03 | 2019-01-25 | Msm创新有限公司 | 矫味试剂盒 |
CN102805753B (zh) * | 2012-08-20 | 2014-09-24 | 深圳万和制药有限公司 | 包含聚乙二醇和电解质的药物组合物 |
CN102805752B (zh) * | 2012-08-20 | 2014-04-02 | 深圳万和制药有限公司 | 复方聚乙二醇电解质散及其制备方法 |
CN102772427B (zh) * | 2012-08-20 | 2014-02-05 | 深圳万和制药有限公司 | 一种复方聚乙二醇电解质组合物 |
PL3473248T3 (pl) | 2012-09-11 | 2022-07-25 | Norgine Bv | Kompozycje zawierające glikol polietylenowy i siarczany metali alkalicznych lub metali ziem alkalicznych do zastosowania jako kompozycje do oczyszczania jelita grubego |
US20140087007A1 (en) * | 2012-09-27 | 2014-03-27 | Braintree Laboratories, Inc. | Bowel cleansing preparations |
KR20140044628A (ko) * | 2012-10-05 | 2014-04-15 | 주식회사태준제약 | 신규한 폴리에틸렌글리콜과 비타민 씨를 함유하는 안정성이 개선된 장관 하제 조성물 |
EP2722058A1 (en) * | 2012-10-19 | 2014-04-23 | Cosmo Technologies Ltd | Solid oral composition containing dyes for use in endoscopic diagnosis |
DE102012024434A1 (de) * | 2012-12-14 | 2014-06-18 | Regalismons S.A. | Verstärkung der entschäumenden Wirkung von Polysiloxanen, zugehöriger Zusammensetzungen und Lösungen |
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KR101423005B1 (ko) | 2013-10-17 | 2014-07-28 | 강윤식 | 장 세정용 조성물 |
KR101420315B1 (ko) | 2014-03-19 | 2014-07-17 | 남봉길 | 약학적 액제 조성물 |
KR102397379B1 (ko) | 2014-03-25 | 2022-05-13 | 리딩 바이오사이언시즈, 인크. | 자가소화의 치료용의 조성물 |
AU2015253178B2 (en) | 2014-04-29 | 2020-03-12 | Colonaryconcepts Llc | Foods, systems, methods, and kits for providing electrolyte replacement |
US9907912B2 (en) * | 2014-09-26 | 2018-03-06 | John B. RANSOME | Gelatin bowel prep with syringe for colonoscopy |
CN104337834B (zh) * | 2014-11-10 | 2017-06-30 | 河北爱能生物科技股份有限公司 | 一种羧甲基壳聚糖灌肠液 |
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CN109223849A (zh) * | 2018-08-10 | 2019-01-18 | 江汉大学 | 一种白菜冻干粉灌肠剂及其制备方法和应用 |
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KR102217932B1 (ko) * | 2019-03-21 | 2021-02-18 | 충남대학교산학협력단 | 비위관 삽입 보조기구 |
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2002
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