CY1107086T1 - Παραγωγα ουριας ως ανταγωνιστες ιντεγκρινης αλφα 4 - Google Patents

Παραγωγα ουριας ως ανταγωνιστες ιντεγκρινης αλφα 4

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Publication number
CY1107086T1
CY1107086T1 CY20071101582T CY071101582T CY1107086T1 CY 1107086 T1 CY1107086 T1 CY 1107086T1 CY 20071101582 T CY20071101582 T CY 20071101582T CY 071101582 T CY071101582 T CY 071101582T CY 1107086 T1 CY1107086 T1 CY 1107086T1
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Cyprus
Prior art keywords
integrine
competitors
alpha
urine
products
Prior art date
Application number
CY20071101582T
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English (en)
Inventor
Mayorga Juan Miguel Jimenez
Tana Jordi Bach
Ontoria Jesus Maria Ontoria
Romero Eloisa Navarro
Original Assignee
Laboratorios Almirall, S.A.
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Application filed by Laboratorios Almirall, S.A. filed Critical Laboratorios Almirall, S.A.
Publication of CY1107086T1 publication Critical patent/CY1107086T1/el

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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
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    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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Abstract

Νέοι ανταγωνιστές της ιντεγκρίνης α4β1 και/ή της ιντεγκρίνης α4β7 γενικού Χημικού Τύπου (Ι): στον οποίον τα R1, R2, R5, L1, L2, Rb, W και Z ορίζονται σύμφωνα με την οποιανδήποτε των αξιώσεων 1 έως 13, το Α αναπαριστά το –CH- ή ένα άτομο αζώτου, και το p είναι από το 0 έως το 4.
CY20071101582T 2001-01-19 2007-12-13 Παραγωγα ουριας ως ανταγωνιστες ιντεγκρινης αλφα 4 CY1107086T1 (el)

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EP02710010A EP1383750B1 (en) 2001-01-19 2002-01-15 Urea derivatives as integrin alpha 4 antagonists

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