CY1107086T1 - Παραγωγα ουριας ως ανταγωνιστες ιντεγκρινης αλφα 4 - Google Patents
Παραγωγα ουριας ως ανταγωνιστες ιντεγκρινης αλφα 4Info
- Publication number
- CY1107086T1 CY1107086T1 CY20071101582T CY071101582T CY1107086T1 CY 1107086 T1 CY1107086 T1 CY 1107086T1 CY 20071101582 T CY20071101582 T CY 20071101582T CY 071101582 T CY071101582 T CY 071101582T CY 1107086 T1 CY1107086 T1 CY 1107086T1
- Authority
- CY
- Cyprus
- Prior art keywords
- integrine
- competitors
- alpha
- urine
- products
- Prior art date
Links
- 210000002700 urine Anatomy 0.000 title 1
- 108010008212 Integrin alpha4beta1 Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 108010043603 integrin alpha4beta7 Proteins 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07D213/40—Acylated substituent nitrogen atom
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract
Νέοι ανταγωνιστές της ιντεγκρίνης α4β1 και/ή της ιντεγκρίνης α4β7 γενικού Χημικού Τύπου (Ι): στον οποίον τα R1, R2, R5, L1, L2, Rb, W και Z ορίζονται σύμφωνα με την οποιανδήποτε των αξιώσεων 1 έως 13, το Α αναπαριστά το –CH- ή ένα άτομο αζώτου, και το p είναι από το 0 έως το 4.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200100126A ES2200617B1 (es) | 2001-01-19 | 2001-01-19 | Derivados de urea como antagonistas de integrinas alfa 4. |
EP02710010A EP1383750B1 (en) | 2001-01-19 | 2002-01-15 | Urea derivatives as integrin alpha 4 antagonists |
Publications (1)
Publication Number | Publication Date |
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CY1107086T1 true CY1107086T1 (el) | 2012-10-24 |
Family
ID=8496447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CY20071101582T CY1107086T1 (el) | 2001-01-19 | 2007-12-13 | Παραγωγα ουριας ως ανταγωνιστες ιντεγκρινης αλφα 4 |
Country Status (33)
Country | Link |
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US (2) | US7253171B2 (el) |
EP (1) | EP1383750B1 (el) |
JP (1) | JP4173003B2 (el) |
KR (1) | KR100861471B1 (el) |
CN (1) | CN100536839C (el) |
AR (1) | AR032256A1 (el) |
AT (1) | ATE374191T1 (el) |
AU (1) | AU2002228048B2 (el) |
BG (1) | BG108004A (el) |
BR (1) | BR0206588A (el) |
CA (1) | CA2434939A1 (el) |
CY (1) | CY1107086T1 (el) |
CZ (1) | CZ20031964A3 (el) |
DE (1) | DE60222647T2 (el) |
DK (1) | DK1383750T3 (el) |
EC (1) | ECSP034707A (el) |
EE (1) | EE200300327A (el) |
ES (2) | ES2200617B1 (el) |
HK (1) | HK1058361A1 (el) |
HU (1) | HUP0303722A3 (el) |
IL (1) | IL156939A0 (el) |
MX (1) | MXPA03006363A (el) |
MY (1) | MY129423A (el) |
NO (1) | NO327002B1 (el) |
NZ (1) | NZ527031A (el) |
PL (1) | PL369120A1 (el) |
PT (1) | PT1383750E (el) |
RU (1) | RU2296120C2 (el) |
SK (1) | SK9232003A3 (el) |
UA (1) | UA81603C2 (el) |
UY (1) | UY27127A1 (el) |
WO (1) | WO2002057242A2 (el) |
ZA (1) | ZA200305535B (el) |
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