CU20160004A7 - Bencil-1 h-pirazolo[3,4-b]piridinas - Google Patents

Bencil-1 h-pirazolo[3,4-b]piridinas

Info

Publication number
CU20160004A7
CU20160004A7 CUP2016000004A CU20160004A CU20160004A7 CU 20160004 A7 CU20160004 A7 CU 20160004A7 CU P2016000004 A CUP2016000004 A CU P2016000004A CU 20160004 A CU20160004 A CU 20160004A CU 20160004 A7 CU20160004 A7 CU 20160004A7
Authority
CU
Cuba
Prior art keywords
piridines
pirazolo
bencil
formula
pyrazolo
Prior art date
Application number
CUP2016000004A
Other languages
English (en)
Inventor
Alexandros Vakalopoulos
Alexey Gromov
Markus Follmann
Damian Brockschnieder
Johannes-Peter Stasch
Tobias Marquardt
Adrian Tersteegen
Frank Wunder
Gorden Redlich
Dieter Lang
Volkhart Min-Jian Li
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CU20160004A7 publication Critical patent/CU20160004A7/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente solicitud se relaciona con bencil-1 H-pirazolo[3,4-b]piridinas novedosas de fórmula (I) ESPACIO PARA LA FÓRMULA
CUP2016000004A 2013-07-10 2016-01-11 Bencil-1 h-pirazolo[3,4-b]piridinas CU20160004A7 (es)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
EP13175889 2013-07-10
EP13175892 2013-07-10
EP13175898 2013-07-10
EP13175899 2013-07-10
EP13175890 2013-07-10
EP13175903 2013-07-10
EP13175896 2013-07-10
EP13175904 2013-07-10
EP13175895 2013-07-10
EP13175894 2013-07-10
PCT/EP2014/064547 WO2015004105A1 (de) 2013-07-10 2014-07-08 Benzyl-1h-pyrazolo[3,4-b]pyridine und ihre verwendung

Publications (1)

Publication Number Publication Date
CU20160004A7 true CU20160004A7 (es) 2016-06-29

Family

ID=51162805

Family Applications (1)

Application Number Title Priority Date Filing Date
CUP2016000004A CU20160004A7 (es) 2013-07-10 2016-01-11 Bencil-1 h-pirazolo[3,4-b]piridinas

Country Status (22)

Country Link
US (1) US9605008B2 (es)
EP (1) EP3019506A1 (es)
JP (1) JP2016523944A (es)
KR (1) KR20160030541A (es)
CN (1) CN105745215A (es)
AP (1) AP2016008970A0 (es)
AU (1) AU2014289312A1 (es)
CA (1) CA2917682A1 (es)
CL (1) CL2016000030A1 (es)
CU (1) CU20160004A7 (es)
DO (1) DOP2016000006A (es)
EA (1) EA201600096A1 (es)
GT (1) GT201600002A (es)
IL (1) IL243525A0 (es)
MX (1) MX2016000258A (es)
PE (1) PE20160201A1 (es)
PH (1) PH12016500065A1 (es)
SG (1) SG11201600038UA (es)
TN (1) TN2016000006A1 (es)
TW (1) TW201542569A (es)
UY (1) UY35652A (es)
WO (1) WO2015004105A1 (es)

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LT3325013T (lt) 2015-07-23 2020-11-10 Bayer Pharma Aktiengesellschaft Tirpios guanilatciklazės (sgc) stimuliatoriai/aktyvatoriai derinyje su nep inhibitoriumi ir (arba) angiotenzino aii antagonistu ir jų naudojimas
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WO2017121692A1 (de) 2016-01-15 2017-07-20 Bayer Pharma Aktiengesellschaft Substituierte sulfamide und ihre verwendung
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ES2985316T3 (es) 2016-10-11 2024-11-05 Bayer Pharma AG Combinación que contiene el estimulador sGC vericuguat y el antagonista de los receptores de corticoides minerales finerenona
US11331308B2 (en) 2016-10-11 2022-05-17 Bayer Pharma Aktiengesellschaft Combination containing sGC activators and mineralocorticoid receptor antagonists
KR102615821B1 (ko) 2017-04-11 2023-12-21 선샤인 레이크 파르마 컴퍼니 리미티드 불소-치환된 인다졸 화합물 및 이의 용도
WO2018234488A1 (en) 2017-06-23 2018-12-27 Basf Se Substituted cyclopropyl derivatives
MA52616A (fr) 2018-05-15 2021-03-24 Bayer Ag Benzamides à substitution 1,3-thiazol-2-yl pour le traitement de maladies associées à la sensibilisation de fibres nerveuses
WO2020164008A1 (en) 2019-02-13 2020-08-20 Bayer Aktiengesellschaft Process for the preparation of porous microparticles
US11884672B2 (en) 2019-05-14 2024-01-30 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin
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Also Published As

Publication number Publication date
AU2014289312A1 (en) 2016-02-11
DOP2016000006A (es) 2016-02-15
JP2016523944A (ja) 2016-08-12
EP3019506A1 (de) 2016-05-18
CL2016000030A1 (es) 2016-08-19
CA2917682A1 (en) 2015-01-15
GT201600002A (es) 2018-12-19
KR20160030541A (ko) 2016-03-18
US9605008B2 (en) 2017-03-28
PH12016500065A1 (en) 2016-07-04
PE20160201A1 (es) 2016-05-06
TN2016000006A1 (en) 2017-07-05
AP2016008970A0 (en) 2016-01-31
IL243525A0 (en) 2016-02-29
US20160145271A1 (en) 2016-05-26
WO2015004105A1 (de) 2015-01-15
TW201542569A (zh) 2015-11-16
EA201600096A1 (ru) 2016-10-31
CN105745215A (zh) 2016-07-06
MX2016000258A (es) 2016-04-28
SG11201600038UA (en) 2016-02-26
UY35652A (es) 2015-01-30

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