SG11201600038UA - Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof - Google Patents
Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereofInfo
- Publication number
- SG11201600038UA SG11201600038UA SG11201600038UA SG11201600038UA SG11201600038UA SG 11201600038U A SG11201600038U A SG 11201600038UA SG 11201600038U A SG11201600038U A SG 11201600038UA SG 11201600038U A SG11201600038U A SG 11201600038UA SG 11201600038U A SG11201600038U A SG 11201600038UA
- Authority
- SG
- Singapore
- Prior art keywords
- pyrazolo
- pyridines
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13175904 | 2013-07-10 | ||
EP13175894 | 2013-07-10 | ||
EP13175889 | 2013-07-10 | ||
EP13175898 | 2013-07-10 | ||
EP13175890 | 2013-07-10 | ||
EP13175895 | 2013-07-10 | ||
EP13175899 | 2013-07-10 | ||
EP13175903 | 2013-07-10 | ||
EP13175892 | 2013-07-10 | ||
EP13175896 | 2013-07-10 | ||
PCT/EP2014/064547 WO2015004105A1 (en) | 2013-07-10 | 2014-07-08 | Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201600038UA true SG11201600038UA (en) | 2016-02-26 |
Family
ID=51162805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201600038UA SG11201600038UA (en) | 2013-07-10 | 2014-07-08 | Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof |
Country Status (22)
Country | Link |
---|---|
US (1) | US9605008B2 (en) |
EP (1) | EP3019506A1 (en) |
JP (1) | JP2016523944A (en) |
KR (1) | KR20160030541A (en) |
CN (1) | CN105745215A (en) |
AP (1) | AP2016008970A0 (en) |
AU (1) | AU2014289312A1 (en) |
CA (1) | CA2917682A1 (en) |
CL (1) | CL2016000030A1 (en) |
CU (1) | CU20160004A7 (en) |
DO (1) | DOP2016000006A (en) |
EA (1) | EA201600096A1 (en) |
GT (1) | GT201600002A (en) |
IL (1) | IL243525A0 (en) |
MX (1) | MX2016000258A (en) |
PE (1) | PE20160201A1 (en) |
PH (1) | PH12016500065A1 (en) |
SG (1) | SG11201600038UA (en) |
TN (1) | TN2016000006A1 (en) |
TW (1) | TW201542569A (en) |
UY (1) | UY35652A (en) |
WO (1) | WO2015004105A1 (en) |
Families Citing this family (12)
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DE102012200349A1 (en) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituted fused pyrimidines and triazines and their use |
BR112017023855A2 (en) | 2015-05-06 | 2018-07-17 | Bayer Pharma Aktiengesellschaft | the use of separate sgc stimulants, scg activators and combinations with pde5 inhibitors for the treatment of multiple sclerosis (ssc) concurrent digital (du) ulcers |
EP3325013B2 (en) | 2015-07-23 | 2023-07-19 | Bayer Pharma Aktiengesellschaft | Stimulators / activators of soluble guanylat cyclase in combination with a nep-inhibitor and an angiotensin aii-antagonist and the use thereof |
WO2017107052A1 (en) | 2015-12-22 | 2017-06-29 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase stimulators |
WO2017121692A1 (en) | 2016-01-15 | 2017-07-20 | Bayer Pharma Aktiengesellschaft | Substituted sulfamides and use of same |
WO2017121700A1 (en) | 2016-01-15 | 2017-07-20 | Bayer Pharma Aktiengesellschaft | 1,3-disubstituted 1h-pyrazolo[3,4-b]pyridine derivatives and use thereof as stimulators of soluble guanylate cyclase |
EP3525778A1 (en) | 2016-10-11 | 2019-08-21 | Bayer Pharma Aktiengesellschaft | Combination containing sgc activators and mineralocorticoid receptor antagonists |
EP3525779A1 (en) | 2016-10-11 | 2019-08-21 | Bayer Pharma Aktiengesellschaft | Combination containing sgc stimulators and mineralocorticoid receptor antagonists |
AU2018252099B2 (en) | 2017-04-11 | 2021-08-12 | Sunshine Lake Pharma Co., Ltd. | Fluorine-substituted indazole compounds and uses thereof |
WO2018234488A1 (en) | 2017-06-23 | 2018-12-27 | Basf Se | Substituted cyclopropyl derivatives |
CN112384213A (en) | 2018-05-15 | 2021-02-19 | 拜耳公司 | 1, 3-thiazol-2-yl substituted benzamides for the treatment of diseases associated with nerve fiber sensitization |
WO2020164008A1 (en) | 2019-02-13 | 2020-08-20 | Bayer Aktiengesellschaft | Process for the preparation of porous microparticles |
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GB9314412D0 (en) | 1993-07-13 | 1993-08-25 | Rhone Poulenc Agriculture | New compositions of matter |
JPH11505524A (en) | 1995-05-01 | 1999-05-21 | 藤沢薬品工業株式会社 | Imidazo 1,2-A pyridine and imidazo 1,2-A pyrididine derivatives and their use as bone resorption inhibitors |
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US6451805B1 (en) | 1997-11-14 | 2002-09-17 | Bayer Aktiengesellschaft | Substituted pyrazole derivatives for the treatment of cardiocirculatory diseases |
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DE10132416A1 (en) | 2001-07-04 | 2003-01-16 | Bayer Ag | New morpholine-bridged pyrazolopyridine derivatives |
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DE602004029025D1 (en) | 2003-05-09 | 2010-10-21 | Asahi Glass Co Ltd | PROCESS FOR PREPARING 3-SUBSTITUTED 2-CHLORO-5-FLUORO-PYRIDINE BZW. A SALT OF IT |
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CN101146796A (en) | 2005-01-26 | 2008-03-19 | 先灵公司 | 3-(indazol-5-yl)-(1,2,4)triazine derivatives and related compounds as protein kinase inhibitors for the treatment of cancer |
WO2006130673A1 (en) | 2005-05-31 | 2006-12-07 | Janssen Pharmaceutica, N.V. | 3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders |
WO2007041052A2 (en) | 2005-09-29 | 2007-04-12 | Merck & Co., Inc. | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
DE102006043443A1 (en) | 2006-09-15 | 2008-03-27 | Bayer Healthcare Ag | Novel aza-bicyclic compounds and their use |
EP2176261B1 (en) | 2007-07-31 | 2012-12-19 | Vertex Pharmaceuticals Incorporated | Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof |
JP2011513483A (en) | 2008-03-10 | 2011-04-28 | バーテックス ファーマシューティカルズ インコーポレイテッド | Pyrimidines and pyridines useful as inhibitors of protein kinases |
EP2373317B1 (en) * | 2008-11-25 | 2016-12-14 | Merck Sharp & Dohme Corp. | 4-amino-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one or 4-amino-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one derivatives as activators of the soluble guanylat cyclase for the treatment of cardiovascular diseases |
DE102009004245A1 (en) | 2009-01-09 | 2010-07-15 | Bayer Schering Pharma Aktiengesellschaft | Novel fused, heteroatom-bridged pyrazole and imidazole derivatives and their use |
EP2432776B1 (en) | 2009-05-21 | 2019-09-11 | Universite Laval | Methyl sulfanyl pyrimidines useful as antiinflammatories, analgesics, and antiepileptics |
US20130178475A1 (en) | 2010-03-17 | 2013-07-11 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
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US20130158028A1 (en) | 2010-06-25 | 2013-06-20 | Bayer Intellectual Property Gmbh | Use of stimulators and activators of soluble guanylate cyclase for treating sickle-cell anemia and conserving blood substitutes |
BR112013000596A2 (en) | 2010-07-09 | 2019-09-24 | Bayer Intelectual Property Gmbh | fused pyridines and thiazines and their uses. |
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CN105308055B (en) | 2013-03-01 | 2017-07-14 | 拜耳制药股份公司 | Annelated pyrimidines class of trifluoromethyl substitution and application thereof |
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-
2014
- 2014-07-08 CA CA2917682A patent/CA2917682A1/en not_active Abandoned
- 2014-07-08 MX MX2016000258A patent/MX2016000258A/en unknown
- 2014-07-08 TN TN2016000006A patent/TN2016000006A1/en unknown
- 2014-07-08 EA EA201600096A patent/EA201600096A1/en unknown
- 2014-07-08 WO PCT/EP2014/064547 patent/WO2015004105A1/en active Application Filing
- 2014-07-08 CN CN201480049852.8A patent/CN105745215A/en active Pending
- 2014-07-08 PE PE2016000026A patent/PE20160201A1/en not_active Application Discontinuation
- 2014-07-08 TW TW103123391A patent/TW201542569A/en unknown
- 2014-07-08 US US14/903,347 patent/US9605008B2/en not_active Expired - Fee Related
- 2014-07-08 KR KR1020167003065A patent/KR20160030541A/en not_active Application Discontinuation
- 2014-07-08 JP JP2016524789A patent/JP2016523944A/en active Pending
- 2014-07-08 UY UY0001035652A patent/UY35652A/en not_active Application Discontinuation
- 2014-07-08 AP AP2016008970A patent/AP2016008970A0/en unknown
- 2014-07-08 AU AU2014289312A patent/AU2014289312A1/en not_active Abandoned
- 2014-07-08 EP EP14736803.9A patent/EP3019506A1/en not_active Withdrawn
- 2014-07-08 SG SG11201600038UA patent/SG11201600038UA/en unknown
-
2016
- 2016-01-07 DO DO2016000006A patent/DOP2016000006A/en unknown
- 2016-01-08 GT GT201600002A patent/GT201600002A/en unknown
- 2016-01-08 PH PH12016500065A patent/PH12016500065A1/en unknown
- 2016-01-08 CL CL2016000030A patent/CL2016000030A1/en unknown
- 2016-01-10 IL IL243525A patent/IL243525A0/en unknown
- 2016-01-11 CU CUP2016000004A patent/CU20160004A7/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN105745215A (en) | 2016-07-06 |
CA2917682A1 (en) | 2015-01-15 |
AP2016008970A0 (en) | 2016-01-31 |
JP2016523944A (en) | 2016-08-12 |
CL2016000030A1 (en) | 2016-08-19 |
WO2015004105A1 (en) | 2015-01-15 |
DOP2016000006A (en) | 2016-02-15 |
IL243525A0 (en) | 2016-02-29 |
GT201600002A (en) | 2018-12-19 |
MX2016000258A (en) | 2016-04-28 |
CU20160004A7 (en) | 2016-06-29 |
AU2014289312A1 (en) | 2016-02-11 |
EP3019506A1 (en) | 2016-05-18 |
EA201600096A1 (en) | 2016-10-31 |
US20160145271A1 (en) | 2016-05-26 |
UY35652A (en) | 2015-01-30 |
US9605008B2 (en) | 2017-03-28 |
PH12016500065A1 (en) | 2016-07-04 |
KR20160030541A (en) | 2016-03-18 |
TW201542569A (en) | 2015-11-16 |
TN2016000006A1 (en) | 2017-07-05 |
PE20160201A1 (en) | 2016-05-06 |
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