CS545984A2 - Zpusob vyroby novych substituovanych derivatu benzofuranalkylovych a benzenthiofenalkylovych kyselin - Google Patents

Zpusob vyroby novych substituovanych derivatu benzofuranalkylovych a benzenthiofenalkylovych kyselin

Info

Publication number
CS545984A2
CS545984A2 CS845459A CS545984A CS545984A2 CS 545984 A2 CS545984 A2 CS 545984A2 CS 845459 A CS845459 A CS 845459A CS 545984 A CS545984 A CS 545984A CS 545984 A2 CS545984 A2 CS 545984A2
Authority
CS
Czechoslovakia
Prior art keywords
substituovanych
benzofuranalkylovych
benzenthiofenalkylovych
kyselin
derivatu
Prior art date
Application number
CS845459A
Other languages
English (en)
Other versions
CS252476B2 (en
Inventor
James Patrick Dunn
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Priority to CS856654A priority Critical patent/CS252495B2/cs
Priority to CS856653A priority patent/CS252494B2/cs
Priority to CS856652A priority patent/CS252493B2/cs
Publication of CS545984A2 publication Critical patent/CS545984A2/cs
Publication of CS252476B2 publication Critical patent/CS252476B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS845459A 1983-07-14 1984-07-13 Method of benzofuranalkyl and benzothiophenylalkyl acids' new substituted derivatives production CS252476B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CS856654A CS252495B2 (cs) 1983-07-14 1985-09-18 Způsob výroby nových substituovaných derivátů benzofuranalkylových a benzothiofenalkylových kyselin
CS856653A CS252494B2 (cs) 1983-07-14 1985-09-18 Způsob výroby nových substituovaných derivátů benzofuranalkylových a benzothiofenalkylových kyselin
CS856652A CS252493B2 (cs) 1983-07-14 1985-09-18 Způsob výroby nových substituove^ých derivátů benzofuranalkylových a benzothiaofenalkylových kyselin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51354583A 1983-07-14 1983-07-14

Publications (2)

Publication Number Publication Date
CS545984A2 true CS545984A2 (en) 1987-01-15
CS252476B2 CS252476B2 (en) 1987-09-17

Family

ID=24043724

Family Applications (1)

Application Number Title Priority Date Filing Date
CS845459A CS252476B2 (en) 1983-07-14 1984-07-13 Method of benzofuranalkyl and benzothiophenylalkyl acids' new substituted derivatives production

Country Status (22)

Country Link
EP (1) EP0132130B1 (cs)
JP (1) JPS6038376A (cs)
KR (1) KR880002533B1 (cs)
AR (1) AR240815A1 (cs)
AT (1) ATE50769T1 (cs)
AU (1) AU567953B2 (cs)
CA (1) CA1241008A (cs)
CS (1) CS252476B2 (cs)
DE (1) DE3481512D1 (cs)
DK (1) DK347484A (cs)
ES (2) ES8604554A1 (cs)
FI (1) FI842738A (cs)
GR (1) GR79949B (cs)
HU (1) HU200450B (cs)
IL (1) IL72409A (cs)
NO (1) NO842878L (cs)
NZ (1) NZ208894A (cs)
PH (1) PH20790A (cs)
PL (4) PL255162A1 (cs)
PT (1) PT78905B (cs)
SU (2) SU1409130A3 (cs)
ZA (1) ZA845445B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226670B1 (en) * 1985-12-04 1991-04-10 Imperial Chemical Industries Plc Process for hydroxyaraldehydes
GB8825505D0 (en) 1988-11-01 1988-12-07 Pfizer Ltd Therapeutic agents
AU704085B2 (en) * 1994-07-27 1999-04-15 Vanderbilt University Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5674891A (en) * 1994-07-27 1997-10-07 The Procter & Gamble Company Dihydrobenzothiophene compounds useful as anti-inflammatory agents
US5684002A (en) * 1994-09-07 1997-11-04 The Procter & Gamble Company Dihydorbenzofuran and related compounds useful as anti-inflammatory agents
US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
GB9814801D0 (en) * 1998-07-09 1998-09-09 Univ Strathclyde Integrin dependent cell adhesion inhibitors
EP1572648B1 (en) 2002-12-10 2008-07-09 Ranbaxy Laboratories, Ltd. 3,6-disubstituted azabicyclo (3.1.0)-hexane derivatives as muscarinic receptor antagonists
TW202345792A (zh) * 2022-04-28 2023-12-01 日商第一三共股份有限公司 苯并噻吩化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2077733B1 (cs) * 1970-02-10 1973-03-16 Roussel Uclaf
DE2909754A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue benzofuran- und benzothiophenderivate, deren herstellung und deren verwendung als arzneimittel
US4237144A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans
DE2931672A1 (de) * 1979-08-04 1981-02-26 Basf Ag Substituierte 2,3-dihydrobenzofurylmethylester, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen
JPS5951275A (ja) * 1982-05-31 1984-03-24 Sumitomo Chem Co Ltd 新規な複素環化合物
DE3460315D1 (en) * 1983-02-19 1986-08-28 Beecham Group Plc Benzofuran and benzothiophene-carboxylic-acid derivatives

Also Published As

Publication number Publication date
ES8604554A1 (es) 1986-02-16
DK347484A (da) 1985-01-15
AR240815A1 (es) 1991-02-28
NZ208894A (en) 1987-01-23
EP0132130B1 (en) 1990-03-07
PL255164A1 (en) 1986-07-15
PT78905B (en) 1986-07-22
ATE50769T1 (de) 1990-03-15
EP0132130A3 (en) 1986-12-10
PT78905A (en) 1984-08-01
ZA845445B (en) 1986-02-26
HU200450B (en) 1990-06-28
ES534324A0 (es) 1986-02-16
SU1614762A3 (ru) 1990-12-15
EP0132130A2 (en) 1985-01-23
JPS6038376A (ja) 1985-02-27
PH20790A (en) 1987-04-14
HUT36108A (en) 1985-08-28
KR850001202A (ko) 1985-03-16
ES8607960A1 (es) 1986-06-16
AU567953B2 (en) 1987-12-10
CA1241008A (en) 1988-08-23
IL72409A0 (en) 1984-11-30
AU3059384A (en) 1985-01-17
PL248729A1 (en) 1986-06-17
SU1409130A3 (ru) 1988-07-07
FI842738A (fi) 1985-01-15
IL72409A (en) 1988-05-31
DK347484D0 (da) 1984-07-13
KR880002533B1 (ko) 1988-11-28
PL146523B1 (en) 1989-02-28
CS252476B2 (en) 1987-09-17
AR240815A2 (es) 1991-02-28
FI842738A0 (fi) 1984-07-09
PL255162A1 (en) 1986-07-15
PL255163A1 (en) 1986-07-15
NO842878L (no) 1985-01-15
ES544539A0 (es) 1986-06-16
PL145622B1 (en) 1988-10-31
PL146833B1 (en) 1989-03-31
DE3481512D1 (de) 1990-04-12
GR79949B (cs) 1984-10-31

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