CS273163B2 - Method of l-carnitine production - Google Patents

Method of l-carnitine production Download PDF

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Publication number
CS273163B2
CS273163B2 CS222085A CS222085A CS273163B2 CS 273163 B2 CS273163 B2 CS 273163B2 CS 222085 A CS222085 A CS 222085A CS 222085 A CS222085 A CS 222085A CS 273163 B2 CS273163 B2 CS 273163B2
Authority
CS
Czechoslovakia
Prior art keywords
carnitine
crotonobetaine
betaine
dsm
butyrobetaine
Prior art date
Application number
CS222085A
Other languages
Czech (cs)
English (en)
Other versions
CS222085A2 (en
Inventor
Hans Dr Kulla
Pavel Dr Lehky
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of CS222085A2 publication Critical patent/CS222085A2/cs
Publication of CS273163B2 publication Critical patent/CS273163B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/007Carnitine; Butyrobetaine; Crotonobetaine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/824Achromobacter

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Prostheses (AREA)
  • Eye Examination Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Catalysts (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CS222085A 1984-03-29 1985-03-27 Method of l-carnitine production CS273163B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH160084 1984-03-29

Publications (2)

Publication Number Publication Date
CS222085A2 CS222085A2 (en) 1990-07-12
CS273163B2 true CS273163B2 (en) 1991-03-12

Family

ID=4214209

Family Applications (1)

Application Number Title Priority Date Filing Date
CS222085A CS273163B2 (en) 1984-03-29 1985-03-27 Method of l-carnitine production

Country Status (25)

Country Link
US (1) US5187093A (ro)
EP (1) EP0158194B1 (ro)
JP (1) JPS60224488A (ro)
CN (1) CN1004146B (ro)
AT (1) ATE64154T1 (ro)
AU (1) AU585216B2 (ro)
BG (1) BG50282A3 (ro)
BR (1) BR8501374A (ro)
CA (1) CA1265757A (ro)
CS (1) CS273163B2 (ro)
DD (1) DD232310A5 (ro)
DE (1) DE3583058D1 (ro)
DK (1) DK165191C (ro)
ES (1) ES8602940A1 (ro)
FI (1) FI86889C (ro)
HU (1) HU193744B (ro)
IE (1) IE58045B1 (ro)
IL (1) IL74552A (ro)
IN (1) IN164247B (ro)
NO (1) NO164918C (ro)
PL (1) PL145712B1 (ro)
RO (1) RO92477B (ro)
SU (1) SU1435159A3 (ro)
YU (1) YU45708B (ro)
ZA (1) ZA851959B (ro)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59183694A (ja) * 1983-04-05 1984-10-18 Hamari Yakuhin Kogyo Kk 光学活性なカルニチンの生化学的製造法
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc L−カルニチンの製造法
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
JPS62275689A (ja) * 1985-12-09 1987-11-30 Bio-Le Kk L−カルニチンの製造法
IE902689A1 (en) * 1989-07-28 1991-02-27 Lonza Ag A method of discontinuous production of l-carnitine by a¹microbiological process
DE4017595A1 (de) * 1990-05-31 1991-12-05 Consortium Elektrochem Ind Maltopentaose produzierende amylasen
DE4106375A1 (de) * 1991-02-28 1992-09-03 Degussa Eine l-carnitin-amidase produzierender mikroorganismus, l-carnitin-amidase, verfahren zu deren gewinnung und deren verwendung
CN1058995C (zh) * 1996-11-08 2000-11-29 江苏省微生物研究所 L-肉碱或其盐的制备方法
KR100255039B1 (ko) 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
DE19749480A1 (de) * 1997-11-08 1999-05-20 Univ Leipzig Verfahren zur Herstellung von L-Carnitin aus Crotonobetain
EP1370663B1 (de) * 2001-01-31 2007-03-07 Lonza Ag Mikrobiologisches verfahren zur herstellung von l-carnitin
US7700074B2 (en) * 2002-02-07 2010-04-20 Pettegrew Jay W Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
US7407778B2 (en) 2002-02-07 2008-08-05 Pettegrew Jay W Compounds, compositions and methods for treating neuropsychiatric disorders
ATE437884T1 (de) * 2003-05-29 2009-08-15 Jay W Pettegrew Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen
US20060257842A1 (en) * 2003-05-29 2006-11-16 Pettegrew Jay W Cryopreservation media and molecules
AU2006265280B2 (en) * 2005-07-05 2011-07-14 Lonza Ag Spray-drying process for producing a dry carnitine powder or granulate

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2313573A (en) * 1938-01-17 1943-03-09 Gen Aniline & Film Corp Capillary active compounds and process of preparing them
US2367878A (en) * 1939-05-04 1945-01-23 Hoffmann La Roche Betaine esters
GB1100295A (en) * 1964-11-30 1968-01-24 Daiichi Seiyaku Company Ltd Cosmetic preparations for hair-nourishing or hair-growing
FR1559839A (ro) * 1968-01-30 1969-03-14
ES370147A1 (es) * 1968-08-29 1971-04-01 Gulf Research Development Co Un procedimiento para fabricar ciclopropilamina.
US3711549A (en) * 1970-05-19 1973-01-16 Gulf Research Development Co Process for manufacturing cyclopropylamine
US3796632A (en) * 1971-12-10 1974-03-12 Toray Industries Process for racemizing alpha-amino-epsilon-caprolactam
DE2751134C2 (de) * 1977-11-16 1986-04-17 Degussa Ag, 6000 Frankfurt Verfahren zur Herstellung von γ-Chlorcarbonsäureestern
IT1142201B (it) * 1980-06-24 1986-10-08 Sigma Tau Ind Farmaceuti Procedimento per la produzione enzimatica di l-carnitina
DE3214953A1 (de) * 1982-04-22 1983-10-27 Hoechst Ag, 6230 Frankfurt Mikrobielle polysaccharide, verfahren zu ihrer herstellung, dafuer geeignete mikroorganismen und verwendung der polysaccharide
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc L−カルニチンの製造法
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
IT1190280B (it) * 1986-04-24 1988-02-16 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di gamma-butirrobetaina

Also Published As

Publication number Publication date
AU585216B2 (en) 1989-06-15
NO164918C (no) 1990-11-28
CS222085A2 (en) 1990-07-12
PL252628A1 (en) 1986-02-25
HUT37653A (en) 1986-01-23
ZA851959B (en) 1985-11-27
HU193744B (en) 1987-11-30
EP0158194A2 (de) 1985-10-16
YU50485A (en) 1987-12-31
DK138085D0 (da) 1985-03-27
FI86889C (fi) 1992-10-26
CN85101191A (zh) 1987-06-10
ES541663A0 (es) 1985-12-01
AU4019285A (en) 1985-10-03
US5187093A (en) 1993-02-16
EP0158194B1 (de) 1991-06-05
YU45708B (sh) 1992-07-20
IN164247B (ro) 1989-02-04
FI850781A0 (fi) 1985-02-26
BR8501374A (pt) 1985-11-26
ES8602940A1 (es) 1985-12-01
NO164918B (no) 1990-08-20
EP0158194A3 (en) 1987-07-22
CN1004146B (zh) 1989-05-10
DK138085A (da) 1985-09-30
DK165191C (da) 1993-03-01
SU1435159A3 (ru) 1988-10-30
FI86889B (fi) 1992-07-15
IE58045B1 (en) 1993-06-16
FI850781L (fi) 1985-09-30
PL145712B1 (en) 1988-10-31
RO92477B (ro) 1987-10-01
DD232310A5 (de) 1986-01-22
IL74552A0 (en) 1985-06-30
RO92477A (ro) 1987-09-30
CA1265757A (en) 1990-02-13
NO851261L (no) 1985-09-30
DK165191B (da) 1992-10-19
IL74552A (en) 1988-12-30
IE850533L (en) 1985-09-29
JPS60224488A (ja) 1985-11-08
DE3583058D1 (de) 1991-07-11
BG50282A3 (en) 1992-06-15
ATE64154T1 (de) 1991-06-15

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