IT1142201B - Procedimento per la produzione enzimatica di l-carnitina - Google Patents

Procedimento per la produzione enzimatica di l-carnitina

Info

Publication number
IT1142201B
IT1142201B IT86253/80A IT8625380A IT1142201B IT 1142201 B IT1142201 B IT 1142201B IT 86253/80 A IT86253/80 A IT 86253/80A IT 8625380 A IT8625380 A IT 8625380A IT 1142201 B IT1142201 B IT 1142201B
Authority
IT
Italy
Prior art keywords
carnitina
procedure
enzymatic production
enzymatic
production
Prior art date
Application number
IT86253/80A
Other languages
English (en)
Other versions
IT8086253A0 (it
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IT8086253A0 publication Critical patent/IT8086253A0/it
Priority to IT86253/80A priority Critical patent/IT1142201B/it
Priority to SE8103851A priority patent/SE443803B/sv
Priority to DE19813123975 priority patent/DE3123975A1/de
Priority to CH4159/81A priority patent/CH650274A5/it
Priority to FR8112332A priority patent/FR2485564B1/fr
Priority to AT0276881A priority patent/AT379615B/de
Priority to GB8119340A priority patent/GB2078742B/en
Priority to JP56098128A priority patent/JPS5739791A/ja
Priority to US06/277,008 priority patent/US4371618A/en
Application granted granted Critical
Publication of IT1142201B publication Critical patent/IT1142201B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/007Carnitine; Butyrobetaine; Crotonobetaine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01108Carnitine 3-dehydrogenase (1.1.1.108)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
IT86253/80A 1980-06-24 1980-06-24 Procedimento per la produzione enzimatica di l-carnitina IT1142201B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT86253/80A IT1142201B (it) 1980-06-24 1980-06-24 Procedimento per la produzione enzimatica di l-carnitina
SE8103851A SE443803B (sv) 1980-06-24 1981-06-18 Forfarande for enzymatisk framstellning av l-karnitin
DE19813123975 DE3123975A1 (de) 1980-06-24 1981-06-19 Verfahren zur enzymatischen herstellung von l-carnitin
FR8112332A FR2485564B1 (fr) 1980-06-24 1981-06-23 Procede pour la production enzymatique de l-carnitine
CH4159/81A CH650274A5 (it) 1980-06-24 1981-06-23 Procedimento per la produzione enzimatica di l-carnitina.
AT0276881A AT379615B (de) 1980-06-24 1981-06-23 Verfahren zur herstellung von l-carnitin
GB8119340A GB2078742B (en) 1980-06-24 1981-06-23 Enzymatic production of l-carnitine
JP56098128A JPS5739791A (en) 1980-06-24 1981-06-23 Production of l-calnitine
US06/277,008 US4371618A (en) 1980-06-24 1981-06-24 Process for enzymatically producing L-carnitine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT86253/80A IT1142201B (it) 1980-06-24 1980-06-24 Procedimento per la produzione enzimatica di l-carnitina

Publications (2)

Publication Number Publication Date
IT8086253A0 IT8086253A0 (it) 1980-06-24
IT1142201B true IT1142201B (it) 1986-10-08

Family

ID=11330417

Family Applications (1)

Application Number Title Priority Date Filing Date
IT86253/80A IT1142201B (it) 1980-06-24 1980-06-24 Procedimento per la produzione enzimatica di l-carnitina

Country Status (9)

Country Link
US (1) US4371618A (it)
JP (1) JPS5739791A (it)
AT (1) AT379615B (it)
CH (1) CH650274A5 (it)
DE (1) DE3123975A1 (it)
FR (1) FR2485564B1 (it)
GB (1) GB2078742B (it)
IT (1) IT1142201B (it)
SE (1) SE443803B (it)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642290A (en) * 1982-12-06 1987-02-10 Sih Charles J Process for preparing a compound for use in the production of L-carnitine
JPS59183694A (ja) * 1983-04-05 1984-10-18 Hamari Yakuhin Kogyo Kk 光学活性なカルニチンの生化学的製造法
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc L−カルニチンの製造法
US4710468A (en) * 1983-10-24 1987-12-01 Sigma-Tau Industrie Pharmaceutiche Riunite S.P.A. Process for preparing L-carnitine and chemical intermediates employed therein
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
US4584270A (en) * 1984-01-23 1986-04-22 Wisconsin Alumni Research Foundation Process for preparing optically-active 4-amino-3-hydroxybutyric acid
FI86889C (fi) * 1984-03-29 1992-10-26 Lonza Ag Foerfarande foer framstaellning av av l-karnitin pao mikrobiologiskt saett
US4751182A (en) * 1984-04-20 1988-06-14 Wisconsin Alumni Research Foundation Process for preparing L-carnitine from DL-carnitine
ZA852808B (en) * 1984-04-20 1985-11-27 Wisconsin Alumni Res Found Process for preparing l-carnitine
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
US5248601A (en) * 1986-03-14 1993-09-28 Franco Francalanci Process for preparing L(-)-carnitine chloride
GB2195630B (en) * 1986-08-26 1990-07-18 Chuo Kaseihin Co Inc Method for producing carnitine, l-carnitineamide hydrolase and method for producing same
JPH0669381B2 (ja) * 1987-12-04 1994-09-07 協和醗酵工業株式会社 カルニチンの製造法
JPH0291049A (ja) * 1988-09-21 1990-03-30 Lonza Ag r―ブチロベタインの製造方法
CA2018137C (en) * 1989-06-14 2000-01-11 Thomas Scholl L-carnitine magnesium citrate
KR100255039B1 (ko) 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
EP1452604A3 (en) 1998-10-27 2005-03-30 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Coenzyme useful for the synthesis of L-Carnitine
US6337197B2 (en) * 1998-10-27 2002-01-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Coenzymes useful for the synthesis of L-carnitine
DE10315760A1 (de) * 2003-04-07 2004-10-21 Basf Ag L-Carnitin Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von substituierten (S)-Alkanolen
KR100565732B1 (ko) 2004-02-26 2006-03-28 씨제이 주식회사 뉴로스포라 크라사 기원의 감마부티로베타인 하이드록실라제
KR100713103B1 (ko) 2005-07-07 2007-05-02 씨제이 주식회사 뉴로스포라 크라사 유래 l-카르니틴 생합성 관련 유전자를포함하는 엔테로박테리아세 속 미생물 및 이를 이용한l-카르니틴의 제조방법
JP4639235B2 (ja) 2005-07-19 2011-02-23 シージェイ チェイルジェダン コーポレーション L−カルニチン生合成関連遺伝子を含む腸内細菌属微生物、およびその微生物を用いたl−カルニチンの産生方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2398046A1 (fr) * 1977-07-18 1979-02-16 Inst Francais Du Petrole Synthese enzymatique de la l-carnitine

Also Published As

Publication number Publication date
CH650274A5 (it) 1985-07-15
JPH022591B2 (it) 1990-01-18
FR2485564A1 (fr) 1981-12-31
US4371618A (en) 1983-02-01
IT8086253A0 (it) 1980-06-24
JPS5739791A (en) 1982-03-05
DE3123975C2 (it) 1990-10-11
SE443803B (sv) 1986-03-10
SE8103851L (sv) 1981-12-25
DE3123975A1 (de) 1982-03-11
GB2078742B (en) 1984-01-18
AT379615B (de) 1986-02-10
ATA276881A (de) 1985-06-15
FR2485564B1 (fr) 1985-07-12
GB2078742A (en) 1982-01-13

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