CS257757B2 - Method of reaction determination between antigen and antibody and reaction agent for realization of this process - Google Patents
Method of reaction determination between antigen and antibody and reaction agent for realization of this process Download PDFInfo
- Publication number
- CS257757B2 CS257757B2 CS823121A CS312182A CS257757B2 CS 257757 B2 CS257757 B2 CS 257757B2 CS 823121 A CS823121 A CS 823121A CS 312182 A CS312182 A CS 312182A CS 257757 B2 CS257757 B2 CS 257757B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- antigen
- reaction
- antibody
- reaction medium
- reactions
- Prior art date
Links
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 43
- 239000000427 antigen Substances 0.000 title claims abstract description 40
- 102000036639 antigens Human genes 0.000 title claims abstract description 39
- 108091007433 antigens Proteins 0.000 title claims abstract description 39
- 238000000034 method Methods 0.000 title claims abstract description 18
- 230000008569 process Effects 0.000 title claims description 3
- 239000003795 chemical substances by application Substances 0.000 title description 2
- 239000012429 reaction media Substances 0.000 claims abstract description 17
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 10
- 230000004520 agglutination Effects 0.000 claims description 10
- 229960000633 dextran sulfate Drugs 0.000 claims description 9
- 239000000872 buffer Substances 0.000 claims description 8
- -1 carboxyl anions Chemical class 0.000 claims description 7
- 229920005615 natural polymer Polymers 0.000 claims description 6
- 229920001059 synthetic polymer Polymers 0.000 claims description 6
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 5
- 229920000669 heparin Polymers 0.000 claims description 5
- 229960002897 heparin Drugs 0.000 claims description 5
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 4
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims description 4
- 239000004471 Glycine Substances 0.000 claims description 2
- 239000012431 aqueous reaction media Substances 0.000 claims description 2
- 239000007853 buffer solution Substances 0.000 claims description 2
- 239000008363 phosphate buffer Substances 0.000 claims description 2
- 239000011541 reaction mixture Substances 0.000 claims description 2
- 230000002441 reversible effect Effects 0.000 claims description 2
- 229920000447 polyanionic polymer Polymers 0.000 abstract description 17
- 239000000523 sample Substances 0.000 description 9
- 239000004816 latex Substances 0.000 description 7
- 229920000126 latex Polymers 0.000 description 7
- 238000003556 assay Methods 0.000 description 6
- 239000000243 solution Substances 0.000 description 5
- 230000008105 immune reaction Effects 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 206010029719 Nonspecific reaction Diseases 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 3
- 238000003018 immunoassay Methods 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 150000001450 anions Chemical class 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920000172 poly(styrenesulfonic acid) Polymers 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 229940005642 polystyrene sulfonic acid Drugs 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 238000003127 radioimmunoassay Methods 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 150000003431 steroids Chemical class 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- RNMCCPMYXUKHAZ-UHFFFAOYSA-N 2-[3,3-diamino-1,2,2-tris(carboxymethyl)cyclohexyl]acetic acid Chemical compound NC1(N)CCCC(CC(O)=O)(CC(O)=O)C1(CC(O)=O)CC(O)=O RNMCCPMYXUKHAZ-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 1
- 229920000623 Cellulose acetate phthalate Polymers 0.000 description 1
- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 206010049190 Red blood cell agglutination Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- GAMPNQJDUFQVQO-UHFFFAOYSA-N acetic acid;phthalic acid Chemical compound CC(O)=O.OC(=O)C1=CC=CC=C1C(O)=O GAMPNQJDUFQVQO-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 229940098773 bovine serum albumin Drugs 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229940081734 cellulose acetate phthalate Drugs 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 229960002086 dextran Drugs 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 230000000984 immunochemical effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000002329 infrared spectrum Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 229940049920 malate Drugs 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004848 nephelometry Methods 0.000 description 1
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- CBXWGGFGZDVPNV-UHFFFAOYSA-N so4-so4 Chemical compound OS(O)(=O)=O.OS(O)(=O)=O CBXWGGFGZDVPNV-UHFFFAOYSA-N 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 150000003457 sulfones Chemical class 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229920005613 synthetic organic polymer Polymers 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Photoreceptors In Electrophotography (AREA)
- Detergent Compositions (AREA)
- Data Exchanges In Wide-Area Networks (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56067333A JPS57182169A (en) | 1981-05-02 | 1981-05-02 | Measuring method for antigen-antibody reaction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS312182A2 CS312182A2 (en) | 1987-09-17 |
| CS257757B2 true CS257757B2 (en) | 1988-06-15 |
Family
ID=13341982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS823121A CS257757B2 (en) | 1981-05-02 | 1982-04-30 | Method of reaction determination between antigen and antibody and reaction agent for realization of this process |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4672045A (en, 2012) |
| EP (1) | EP0064274B1 (en, 2012) |
| JP (1) | JPS57182169A (en, 2012) |
| KR (1) | KR880001533B1 (en, 2012) |
| AT (1) | ATE12010T1 (en, 2012) |
| AU (1) | AU559966B2 (en, 2012) |
| CA (1) | CA1195925A (en, 2012) |
| CS (1) | CS257757B2 (en, 2012) |
| DD (1) | DD202178A5 (en, 2012) |
| DE (1) | DE3262469D1 (en, 2012) |
| DK (1) | DK158481C (en, 2012) |
| ES (1) | ES8302313A1 (en, 2012) |
| HU (1) | HU188057B (en, 2012) |
| IL (1) | IL65767A (en, 2012) |
| NO (1) | NO159820C (en, 2012) |
| PT (1) | PT74835B (en, 2012) |
| SU (1) | SU1554782A3 (en, 2012) |
| ZA (1) | ZA822726B (en, 2012) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61241665A (ja) * | 1985-04-18 | 1986-10-27 | Toyobo Co Ltd | 安定化された固相試薬 |
| US5866322A (en) * | 1988-01-29 | 1999-02-02 | Abbott Laboratories | Method for performing Rubella assay |
| US5459078A (en) * | 1988-01-29 | 1995-10-17 | Abbott Laboratories | Methods and reagents for performing ion-capture digoxin assays |
| US5459080A (en) * | 1988-01-29 | 1995-10-17 | Abbott Laboratories | Ion-capture assays using a specific binding member conjugated to carboxymethylamylose |
| US5141853A (en) * | 1988-07-22 | 1992-08-25 | Abbott Laboratories | Determination of ammonia levels in a sample |
| JPH0750110B2 (ja) * | 1988-12-22 | 1995-05-31 | 積水化学工業株式会社 | 免疫測定法 |
| JPH0750108B2 (ja) * | 1988-12-26 | 1995-05-31 | 積水化学工業株式会社 | 免疫反応測定法 |
| JP3267613B2 (ja) * | 1991-05-30 | 2002-03-18 | アボツト・ラボラトリーズ | イオン捕獲結合アッセイにおける非特異的結合遮断薬を含む試薬 |
| DE4328684A1 (de) * | 1993-08-26 | 1995-03-02 | Boehringer Mannheim Gmbh | Verfahren zur Bestimmung eines Analyten nach dem Agglutinationsprinzip |
| US5486479A (en) * | 1994-05-02 | 1996-01-23 | Mitsubishi Chemical Corporation | Buffer for immunoassay, kit including same and immunoassay method using said buffer |
| RU2170434C2 (ru) * | 1996-09-12 | 2001-07-10 | Мешандин Алексей Гаврилович | Способ агглютинационного иммунологического анализа |
| JP2003066047A (ja) * | 2001-06-14 | 2003-03-05 | Matsushita Electric Ind Co Ltd | 免疫反応測定方法及びそれに用いる免疫反応測定用試薬 |
| DE60225788T2 (de) * | 2001-12-27 | 2008-07-17 | Matsushita Electric Industrial Co., Ltd., Kadoma | Immunreaktionsmessverfahren für die immunreaktionsmessung |
| KR20050083623A (ko) * | 2002-12-10 | 2005-08-26 | 마쯔시다덴기산교 가부시키가이샤 | 면역반응 측정방법 |
| AU2004225599B2 (en) * | 2003-03-31 | 2008-09-04 | Denka Company Limited | Turbidimetric immunoassy for lipoprotein (a) and reagent therefor |
| JP4580180B2 (ja) * | 2004-02-26 | 2010-11-10 | デンカ生研株式会社 | 免疫測定法用測定値低下抑制剤及びそれを用いた免疫測定法 |
| JP5238190B2 (ja) * | 2007-05-24 | 2013-07-17 | 株式会社ビーエル | ヒアルロン酸存在下における免疫測定法及びそれに用いられる物 |
| JP2010127827A (ja) * | 2008-11-28 | 2010-06-10 | Abbott Japan Co Ltd | 非特異的相互作用抑制剤及びその診断測定系への応用 |
| JP5535601B2 (ja) * | 2009-12-01 | 2014-07-02 | デンカ生研株式会社 | 免疫測定法用測定値低下抑制剤及びそれを用いた免疫測定法 |
| JP6116268B2 (ja) * | 2013-01-31 | 2017-04-19 | デンカ生研株式会社 | 生体粘膜由来検体測定イムノアッセイにおいて偽陰性を抑制する方法 |
| JP6675834B2 (ja) * | 2015-05-21 | 2020-04-08 | デンカ生研株式会社 | イムノクロマト試験片及びそれを用いたイムノクロマト法 |
| JP6651794B2 (ja) * | 2015-11-05 | 2020-02-19 | 富士レビオ株式会社 | 心筋トロポニンｉ測定試薬及び方法 |
| WO2017179611A1 (ja) * | 2016-04-13 | 2017-10-19 | 株式会社Ｌｓｉメディエンス | 硫酸化多糖類を用いた免疫学的測定法 |
| CN115335700A (zh) * | 2020-03-31 | 2022-11-11 | 富士瑞必欧株式会社 | 血中β淀粉样蛋白的免疫测定方法及用于该方法的试剂盒 |
| CN113030470B (zh) * | 2021-02-24 | 2022-03-18 | 江西英大生物技术有限公司 | 肌酸激酶同工酶测定试剂盒 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4148869A (en) * | 1975-03-06 | 1979-04-10 | Baxter Travenol Laboratories, Inc. | Immunological reagent and method of using same |
| US4162192A (en) * | 1978-09-28 | 1979-07-24 | Juridical Foundation | Method for purification of HBs antigen |
| US4223005A (en) * | 1979-02-15 | 1980-09-16 | University Of Illinois Foundation | Antibody coated bacteria |
-
1981
- 1981-05-02 JP JP56067333A patent/JPS57182169A/ja active Granted
-
1982
- 1982-04-19 AU AU82823/82A patent/AU559966B2/en not_active Expired
- 1982-04-21 ZA ZA822726A patent/ZA822726B/xx unknown
- 1982-04-28 DE DE8282103639T patent/DE3262469D1/de not_active Expired
- 1982-04-28 EP EP82103639A patent/EP0064274B1/en not_active Expired
- 1982-04-28 DK DK190682A patent/DK158481C/da active
- 1982-04-28 KR KR8201863A patent/KR880001533B1/ko not_active Expired
- 1982-04-28 AT AT82103639T patent/ATE12010T1/de not_active IP Right Cessation
- 1982-04-29 ES ES511797A patent/ES8302313A1/es not_active Expired
- 1982-04-29 IL IL65767A patent/IL65767A/xx not_active IP Right Cessation
- 1982-04-30 HU HU821359A patent/HU188057B/hu not_active IP Right Cessation
- 1982-04-30 DD DD82239478A patent/DD202178A5/de not_active IP Right Cessation
- 1982-04-30 NO NO821444A patent/NO159820C/no unknown
- 1982-04-30 PT PT74835A patent/PT74835B/pt not_active IP Right Cessation
- 1982-04-30 CS CS823121A patent/CS257757B2/cs unknown
- 1982-05-03 CA CA000402117A patent/CA1195925A/en not_active Expired
- 1982-05-03 SU SU823430145A patent/SU1554782A3/ru active
-
1984
- 1984-10-09 US US06/658,456 patent/US4672045A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR830010384A (ko) | 1983-12-30 |
| AU559966B2 (en) | 1987-03-26 |
| US4672045A (en) | 1987-06-09 |
| DK158481B (da) | 1990-05-21 |
| HU188057B (en) | 1986-03-28 |
| NO159820C (no) | 1989-02-08 |
| EP0064274B1 (en) | 1985-02-27 |
| JPS6367864B2 (en, 2012) | 1988-12-27 |
| CA1195925A (en) | 1985-10-29 |
| IL65767A (en) | 1985-06-30 |
| PT74835A (en) | 1982-05-01 |
| DD202178A5 (de) | 1983-08-31 |
| DE3262469D1 (en) | 1985-04-04 |
| ES511797A0 (es) | 1983-02-01 |
| ZA822726B (en) | 1983-11-30 |
| NO821444L (no) | 1982-11-03 |
| JPS57182169A (en) | 1982-11-09 |
| KR880001533B1 (ko) | 1988-08-19 |
| CS312182A2 (en) | 1987-09-17 |
| DK158481C (da) | 1990-10-08 |
| NO159820B (no) | 1988-10-31 |
| EP0064274A1 (en) | 1982-11-10 |
| ATE12010T1 (de) | 1985-03-15 |
| AU8282382A (en) | 1982-07-01 |
| DK190682A (da) | 1982-11-03 |
| PT74835B (en) | 1983-10-28 |
| ES8302313A1 (es) | 1983-02-01 |
| SU1554782A3 (ru) | 1990-03-30 |
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