CS248012B2 - Production method of the raw material containing heparin with the enriched of active compound - Google Patents

Production method of the raw material containing heparin with the enriched of active compound Download PDF

Info

Publication number
CS248012B2
CS248012B2 CS801898A CS189880A CS248012B2 CS 248012 B2 CS248012 B2 CS 248012B2 CS 801898 A CS801898 A CS 801898A CS 189880 A CS189880 A CS 189880A CS 248012 B2 CS248012 B2 CS 248012B2
Authority
CS
Czechoslovakia
Prior art keywords
heparin
content
temperature
raw material
range
Prior art date
Application number
CS801898A
Other languages
Czech (cs)
English (en)
Inventor
Istvan Takacs
Gyorgy Kerey
Janos Illes
Peter Rudolf
Pal Gere
Laszlo Czebe
Erzsebet Neszmelyi
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of CS248012B2 publication Critical patent/CS248012B2/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CS801898A 1979-03-21 1980-03-19 Production method of the raw material containing heparin with the enriched of active compound CS248012B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79RI705A HU177887B (en) 1979-03-21 1979-03-21 Process for preparing a raw material containing heparin

Publications (1)

Publication Number Publication Date
CS248012B2 true CS248012B2 (en) 1987-01-15

Family

ID=11001090

Family Applications (2)

Application Number Title Priority Date Filing Date
CS801898A CS248012B2 (en) 1979-03-21 1980-03-19 Production method of the raw material containing heparin with the enriched of active compound
CS801897A CS248011B2 (en) 1979-03-21 1980-03-19 Preparation method of water extracts of permanent composition with low content of fat and other contaminating components with high content of heparin

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS801897A CS248011B2 (en) 1979-03-21 1980-03-19 Preparation method of water extracts of permanent composition with low content of fat and other contaminating components with high content of heparin

Country Status (26)

Country Link
US (1) US4315923A (en, 2012)
JP (2) JPS55164201A (en, 2012)
AR (2) AR222215A1 (en, 2012)
AT (2) AT368004B (en, 2012)
AU (2) AU533021B2 (en, 2012)
BE (2) BE882370A (en, 2012)
BR (2) BR8001717A (en, 2012)
CA (2) CA1152894A (en, 2012)
CS (2) CS248012B2 (en, 2012)
DD (2) DD149532A5 (en, 2012)
DE (2) DE3011062A1 (en, 2012)
DK (2) DK166393C (en, 2012)
ES (2) ES8102580A1 (en, 2012)
FR (2) FR2451743A1 (en, 2012)
GB (2) GB2045272B (en, 2012)
GR (2) GR67681B (en, 2012)
HU (1) HU177887B (en, 2012)
IN (1) IN153527B (en, 2012)
IT (2) IT1133068B (en, 2012)
NL (2) NL8001693A (en, 2012)
NZ (2) NZ193188A (en, 2012)
PL (2) PL134709B1 (en, 2012)
SE (2) SE453725B (en, 2012)
SU (2) SU1366042A3 (en, 2012)
YU (2) YU76580A (en, 2012)
ZA (2) ZA801480B (en, 2012)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE449753B (sv) * 1978-11-06 1987-05-18 Choay Sa Mukopolysackaridkomposition med reglerande verkan pa koagulation, lekemedel innehallande densamma samt forfarande for framstellning derav
US4692435A (en) * 1978-11-06 1987-09-08 Choay, S.A. Mucopolysaccharide composition having a regulatory action on coagulation, medicament containing same and process of preparation
US4826600A (en) * 1987-06-24 1989-05-02 Amoco Corporation Process for treatment of wastewater
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
EP0996642B1 (en) * 1997-07-16 2006-01-11 Akzo Nobel N.V. Process for the production of heparin
CN1662151A (zh) * 2002-06-19 2005-08-31 肯技术股份有限公司 包含粘膜副产品的动物饲料组合物
CN118829681A (zh) * 2022-03-08 2024-10-22 霍里松Ip有限公司 来自被屠宰动物的废弃组织的肝素以及天然蛋白质和肽的混合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2410084A (en) * 1943-12-09 1946-10-29 Upjohn Co Recovery of heparin
US2587924A (en) * 1948-05-27 1952-03-04 Univ Alberta Methods of producing heparin
US2571679A (en) * 1948-07-08 1951-10-16 Carlo Erba S A Process for preparing purified heparin
DE950594C (de) * 1953-07-01 1956-10-11 Upjohn Co Verfahren zur Gewinnung von Heparin
GB872214A (en) * 1957-09-23 1961-07-05 Upjohn Co Extraction process for the recovery of heparin
US2989438A (en) * 1958-12-29 1961-06-20 Roussel Uclaf Process of purifying heparin, and product produced therefrom
GB1221784A (en) * 1967-04-07 1971-02-10 John Ernest Scott Precipitation of heparin from aqueous solution
US3451996A (en) * 1968-02-12 1969-06-24 Thompson Farms Co Method for the preparation of heparin
IT1019525B (it) * 1972-03-21 1977-11-30 Ferdinando D Metodo apparecchio e prodotto per formare complessi stabili di polia nioni
DE2646678C2 (de) * 1975-10-31 1985-11-28 A. H. Robins Co. Inc., Richmond, Va. Verfahren zur Herstellung eines entfetteten Heparin-Gewebes
DE2646677C2 (de) * 1975-10-31 1985-11-07 A. H. Robins Co. Inc., Richmond, Va. Verfahren zum Tempern von gefrorenem, Heparin führendem tierischem Gewebe
US4188467A (en) * 1975-10-31 1980-02-12 A. H. Robins Company, Incorporated Process for tempering tissue for heparin production
US4192916A (en) * 1975-10-31 1980-03-11 A. H. Robins Company, Incorporated Process for producing defatted heparin tissue for heparin production
DE2652272C2 (de) * 1976-11-12 1979-02-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Heparin
DE2660052A1 (de) * 1976-11-12 1979-01-25 Schering Ag Verfahren zur herstellung von heparin
US4175182A (en) * 1978-07-03 1979-11-20 Research Corporation Separation of high-activity heparin by affinity chromatography on supported protamine

Also Published As

Publication number Publication date
BE882369A (fr) 1980-09-22
DE3011062A1 (de) 1980-10-02
HU177887B (en) 1982-01-28
CS248011B2 (en) 1987-01-15
AR219226A1 (es) 1980-07-31
DE3010972A1 (de) 1980-10-02
GB2045271B (en) 1983-04-20
DK166393B (da) 1993-05-10
SU1375115A3 (ru) 1988-02-15
PL134709B1 (en) 1985-09-30
YU76580A (en) 1983-10-31
CA1137081A (en) 1982-12-07
IT1133074B (it) 1986-07-09
AU533021B2 (en) 1983-10-27
FR2451743B1 (en, 2012) 1983-05-27
DD149532A5 (de) 1981-07-15
YU76980A (en) 1984-02-29
IT8067444A0 (it) 1980-03-21
NL8001693A (nl) 1980-09-23
SE453725B (sv) 1988-02-29
PL128250B1 (en) 1984-01-31
ZA801480B (en) 1981-03-25
NZ193215A (en) 1984-11-09
ES490538A0 (es) 1981-02-16
SE8002125L (sv) 1980-09-22
FR2451744B1 (en, 2012) 1983-07-29
DK166504C (da) 1993-10-18
IT1133068B (it) 1986-07-09
DK119480A (da) 1980-09-22
CA1152894A (en) 1983-08-30
SU1366042A3 (ru) 1988-01-07
GB2045272B (en) 1983-03-30
BE882370A (fr) 1980-09-22
JPH0232282B2 (en, 2012) 1990-07-19
JPS55164202A (en) 1980-12-20
AU5663780A (en) 1980-09-25
JPH039121B2 (en, 2012) 1991-02-07
DD149467A5 (de) 1981-07-15
AU5663680A (en) 1980-09-25
DK119780A (da) 1980-09-22
GB2045271A (en) 1980-10-29
ZA801564B (en) 1981-03-25
ES8102581A1 (es) 1981-02-16
AR222215A1 (es) 1981-04-30
IN153527B (en, 2012) 1984-07-21
FR2451743A1 (fr) 1980-10-17
NL8001695A (nl) 1980-09-23
GB2045272A (en) 1980-10-29
SE451297B (sv) 1987-09-28
FR2451744A1 (fr) 1980-10-17
SE8002126L (sv) 1980-09-22
PL222794A1 (en, 2012) 1981-01-02
NZ193188A (en) 1984-11-09
GR67681B (en, 2012) 1981-09-04
AU529809B2 (en) 1983-06-23
ATA144280A (de) 1981-07-15
BR8001717A (pt) 1980-11-18
DK166504B (da) 1993-06-01
BR8001711A (pt) 1980-11-18
ATA134880A (de) 1982-01-15
AT365927B (de) 1982-02-25
IT8067438A0 (it) 1980-03-21
DE3010972C2 (en, 2012) 1989-08-31
GR67682B (en, 2012) 1981-09-04
PL222906A1 (en, 2012) 1981-01-02
ES490537A0 (es) 1981-02-16
AT368004B (de) 1982-08-25
DK166393C (da) 1993-09-27
JPS55164201A (en) 1980-12-20
ES8102580A1 (es) 1981-02-16
US4315923A (en) 1982-02-16

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