GB1221784A - Precipitation of heparin from aqueous solution - Google Patents

Precipitation of heparin from aqueous solution

Info

Publication number
GB1221784A
GB1221784A GB1612667A GB1612667A GB1221784A GB 1221784 A GB1221784 A GB 1221784A GB 1612667 A GB1612667 A GB 1612667A GB 1612667 A GB1612667 A GB 1612667A GB 1221784 A GB1221784 A GB 1221784A
Authority
GB
United Kingdom
Prior art keywords
heparin
concentration
precipitation
aqueous solution
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1612667A
Inventor
John Ernest Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB1612667A priority Critical patent/GB1221784A/en
Priority to FR1577360D priority patent/FR1577360A/fr
Publication of GB1221784A publication Critical patent/GB1221784A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

1,221,784. Heparin. J. E. SCOTT. 21 Feb., 1968 [7 April, 1967], No. 16126/67. Heading C3U. Heparin is recovered from, e.g. lung or mucosal tissue or impure solid heparin, by treatment thereof with an aqueous solution of a potassium salt of a substituted or unsubstituted C 1-6 aliphatic carboxylic acid, and having a K ion activity at least equal to that of KCl at the equivalent K concentration, treatment being effected under concentration and temperature conditions such that substantially all the heparin present is dissolved, and the solution being finally cooled, after removal of insolubles, to precipitate K heparinate. Precipitation may be at pH 4À5-9À5. The salt concentration may be at least 1.0 M. The salt may be K acetate, citrate or trichloracetate. The conditions may be adjusted to yield the more active heparin in the precipitate.
GB1612667A 1967-04-07 1967-04-07 Precipitation of heparin from aqueous solution Expired GB1221784A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB1612667A GB1221784A (en) 1967-04-07 1967-04-07 Precipitation of heparin from aqueous solution
FR1577360D FR1577360A (en) 1967-04-07 1968-04-05

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1612667A GB1221784A (en) 1967-04-07 1967-04-07 Precipitation of heparin from aqueous solution

Publications (1)

Publication Number Publication Date
GB1221784A true GB1221784A (en) 1971-02-10

Family

ID=10071661

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1612667A Expired GB1221784A (en) 1967-04-07 1967-04-07 Precipitation of heparin from aqueous solution

Country Status (2)

Country Link
FR (1) FR1577360A (en)
GB (1) GB1221784A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4315923A (en) * 1979-03-21 1982-02-16 Richter Gedeon Vegyeszeti Gyar Rt Process for the production of organ extracts with high herparin content

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1189298B (en) * 1982-06-18 1988-02-04 Manetti & Roberts Italo Brit PROCEDURE FOR THE PRODUCTION OF DERMATAN-SULPHATE AND EPARAN-SULPHATE MINOGLICANS GLYCOS SUBSTANTIALLY PURE AND THEIR PHARMACEUTICAL USE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4315923A (en) * 1979-03-21 1982-02-16 Richter Gedeon Vegyeszeti Gyar Rt Process for the production of organ extracts with high herparin content

Also Published As

Publication number Publication date
FR1577360A (en) 1969-08-08

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