CS219344B2 - Method of preparation of the pleuromutiline glycoside - Google Patents

Method of preparation of the pleuromutiline glycoside Download PDF

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Publication number
CS219344B2
CS219344B2 CS804091A CS409178A CS219344B2 CS 219344 B2 CS219344 B2 CS 219344B2 CS 804091 A CS804091 A CS 804091A CS 409178 A CS409178 A CS 409178A CS 219344 B2 CS219344 B2 CS 219344B2
Authority
CS
Czechoslovakia
Prior art keywords
deoxy
thioacetoxy
acetyl
preparation
mutilin
Prior art date
Application number
CS804091A
Other languages
Czech (cs)
English (en)
Inventor
Ramakrishnan Nagarajan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS219344B2 publication Critical patent/CS219344B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS804091A 1977-12-08 1978-12-04 Method of preparation of the pleuromutiline glycoside CS219344B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/858,507 US4130709A (en) 1977-12-08 1977-12-08 Pleuromutilin glycoside derivatives

Publications (1)

Publication Number Publication Date
CS219344B2 true CS219344B2 (en) 1983-03-25

Family

ID=25328471

Family Applications (2)

Application Number Title Priority Date Filing Date
CS804091A CS219344B2 (en) 1977-12-08 1978-12-04 Method of preparation of the pleuromutiline glycoside
CS788007A CS219342B2 (en) 1977-12-08 1978-12-04 Method of preparation of the glycoside of the pleuromutiline

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS788007A CS219342B2 (en) 1977-12-08 1978-12-04 Method of preparation of the glycoside of the pleuromutiline

Country Status (28)

Country Link
US (1) US4130709A (de)
EP (1) EP0002588B1 (de)
JP (1) JPS5498751A (de)
AT (1) AT362065B (de)
AU (1) AU524665B2 (de)
BE (1) BE872489A (de)
CA (1) CA1109866A (de)
CH (1) CH639103A5 (de)
CS (2) CS219344B2 (de)
DD (1) DD139858A5 (de)
DE (1) DE2862226D1 (de)
DK (1) DK539578A (de)
ES (1) ES475854A1 (de)
FI (1) FI783709A7 (de)
FR (1) FR2411205A1 (de)
GB (1) GB2009738B (de)
GR (1) GR72774B (de)
HU (1) HU181429B (de)
IE (1) IE47533B1 (de)
IL (1) IL56115A (de)
IT (1) IT1160316B (de)
LU (1) LU80619A1 (de)
PL (1) PL123850B1 (de)
PT (1) PT68857A (de)
RO (3) RO84425B (de)
SU (1) SU902666A3 (de)
YU (1) YU281878A (de)
ZA (1) ZA786872B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5594359A (en) * 1979-01-12 1980-07-17 Sandoz Ag Novel pleuromutilin derivatives*their manufacture and use
US5041534A (en) * 1983-03-22 1991-08-20 Merrell Dow Pharmaceuticals Process for preparing antibiotic L 17054
FR2551442B1 (fr) * 1983-09-05 1987-04-30 Centre Nat Rech Scient Nouveaux derives furaniques, leur preparation et leur application
US5077398A (en) * 1986-11-18 1991-12-31 Merck & Co., Inc. Process for isolation of avermectin B1 components with improved purity and subsequent isolaton of B2 components
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof
AT400674B (de) * 1991-07-24 1996-02-26 Biochemie Gmbh Pharmazeutische pleuromutilin-zubereitung
JP3816570B2 (ja) * 1996-02-16 2006-08-30 塩水港精糖株式会社 アシル化剤
GB9614017D0 (en) * 1996-07-04 1996-09-04 Biochemie Gmbh Organic compounds
UY25225A1 (es) 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
ES2182703B1 (es) * 2001-06-18 2004-06-01 Consejo Superior De Investigaciones Cientificas Un procedimiento enzimatico para obtener 4-0-b-d-galactopiranosil-d-xilosa, 4-o-b-d-galactopiranosil-d-xilosa obtenida de acuerdo con el pr cedimiento, composiciones que la contienen y su uso en la evaluacion de la lactasa intestinal.
GB0218578D0 (en) * 2002-08-09 2002-09-18 Glaxo Group Ltd Novel method
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
JP5460947B2 (ja) 2003-09-03 2014-04-02 グラクソ グループ リミテッド 新規調製方法、塩、組成物及び使用
US6838576B1 (en) 2003-10-23 2005-01-04 3M Innovative Properties Company Process for preparing functional group-containing olefinic compounds
US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
US20060046962A1 (en) 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
GB0513058D0 (en) * 2005-06-27 2005-08-03 Sandoz Ag Organic compounds
US7998927B2 (en) * 2006-06-23 2011-08-16 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
US8084022B2 (en) 2006-06-23 2011-12-27 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
US20090326193A1 (en) * 2006-06-23 2009-12-31 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
US8173594B2 (en) * 2006-06-23 2012-05-08 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
US8226949B2 (en) * 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
EP1972618A1 (de) 2007-03-20 2008-09-24 Nabriva Therapeutics AG Pleuromutilin-Derivate zur Behandlung von Krankheiten vermittelt durch Mikroben
CA2756690C (en) 2008-03-28 2016-08-16 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
US8440631B2 (en) 2008-12-22 2013-05-14 Aegis Therapeutics, Llc Compositions for drug administration
PL3415139T3 (pl) 2011-06-14 2022-07-11 Neurelis, Inc. Podawanie benzodiazepiny
US20170274087A1 (en) * 2014-09-19 2017-09-28 Emory University Saccharide analogs and agents for the diagnosis and therapy of bacterial infections
JP6818019B2 (ja) 2015-06-17 2021-01-20 ナブリヴァ セラピュティクス ゲーエムベーハー レファムリンの注射可能医薬組成物

Also Published As

Publication number Publication date
RO80082B (ro) 1983-01-30
CH639103A5 (fr) 1983-10-31
AU4216278A (en) 1979-06-14
PT68857A (en) 1979-01-01
DE2862226D1 (en) 1983-05-11
RO84425B (ro) 1984-08-30
JPS5498751A (en) 1979-08-03
IL56115A0 (en) 1979-03-12
DD139858A5 (de) 1980-01-23
FR2411205A1 (fr) 1979-07-06
PL123850B1 (en) 1982-12-31
US4130709A (en) 1978-12-19
CA1109866A (en) 1981-09-29
RO84426A (ro) 1984-06-21
RO84425A (ro) 1984-06-21
ATA871578A (de) 1980-09-15
ES475854A1 (es) 1980-05-16
RO84426B (ro) 1984-08-30
BE872489A (fr) 1979-06-05
LU80619A1 (fr) 1979-06-05
GB2009738B (en) 1982-11-10
IE782421L (en) 1979-06-08
YU281878A (en) 1983-06-30
DK539578A (da) 1979-07-05
FR2411205B1 (de) 1981-08-14
SU902666A3 (ru) 1982-01-30
IL56115A (en) 1984-01-31
GR72774B (de) 1983-12-05
HU181429B (en) 1983-07-28
PL211492A1 (pl) 1979-11-19
EP0002588A1 (de) 1979-06-27
FI783709A7 (fi) 1979-06-09
IE47533B1 (en) 1984-04-18
CS219342B2 (en) 1983-03-25
AT362065B (de) 1981-04-27
IT7830657A0 (it) 1978-12-06
GB2009738A (en) 1979-06-20
IT1160316B (it) 1987-03-11
EP0002588B1 (de) 1983-04-06
AU524665B2 (en) 1982-09-30
RO80082A (ro) 1983-02-01
ZA786872B (en) 1980-08-27

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