CS219342B2 - Method of preparation of the glycoside of the pleuromutiline - Google Patents

Method of preparation of the glycoside of the pleuromutiline Download PDF

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Publication number
CS219342B2
CS219342B2 CS788007A CS800778A CS219342B2 CS 219342 B2 CS219342 B2 CS 219342B2 CS 788007 A CS788007 A CS 788007A CS 800778 A CS800778 A CS 800778A CS 219342 B2 CS219342 B2 CS 219342B2
Authority
CS
Czechoslovakia
Prior art keywords
thio
acetyl
deoxy
anomers
tri
Prior art date
Application number
CS788007A
Other languages
Czech (cs)
English (en)
Inventor
Ramakrishnan Nagarajan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to CS804090A priority Critical patent/CS219343B2/cs
Publication of CS219342B2 publication Critical patent/CS219342B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS788007A 1977-12-08 1978-12-04 Method of preparation of the glycoside of the pleuromutiline CS219342B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS804090A CS219343B2 (cs) 1977-12-08 1980-06-10 Způsob přípravy glykosidů plsuromutilinu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/858,507 US4130709A (en) 1977-12-08 1977-12-08 Pleuromutilin glycoside derivatives

Publications (1)

Publication Number Publication Date
CS219342B2 true CS219342B2 (en) 1983-03-25

Family

ID=25328471

Family Applications (2)

Application Number Title Priority Date Filing Date
CS788007A CS219342B2 (en) 1977-12-08 1978-12-04 Method of preparation of the glycoside of the pleuromutiline
CS804091A CS219344B2 (en) 1977-12-08 1978-12-04 Method of preparation of the pleuromutiline glycoside

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS804091A CS219344B2 (en) 1977-12-08 1978-12-04 Method of preparation of the pleuromutiline glycoside

Country Status (28)

Country Link
US (1) US4130709A (ro)
EP (1) EP0002588B1 (ro)
JP (1) JPS5498751A (ro)
AT (1) AT362065B (ro)
AU (1) AU524665B2 (ro)
BE (1) BE872489A (ro)
CA (1) CA1109866A (ro)
CH (1) CH639103A5 (ro)
CS (2) CS219342B2 (ro)
DD (1) DD139858A5 (ro)
DE (1) DE2862226D1 (ro)
DK (1) DK539578A (ro)
ES (1) ES475854A1 (ro)
FI (1) FI783709A7 (ro)
FR (1) FR2411205A1 (ro)
GB (1) GB2009738B (ro)
GR (1) GR72774B (ro)
HU (1) HU181429B (ro)
IE (1) IE47533B1 (ro)
IL (1) IL56115A (ro)
IT (1) IT1160316B (ro)
LU (1) LU80619A1 (ro)
PL (1) PL123850B1 (ro)
PT (1) PT68857A (ro)
RO (3) RO84425B (ro)
SU (1) SU902666A3 (ro)
YU (1) YU281878A (ro)
ZA (1) ZA786872B (ro)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA80175B (en) * 1979-01-12 1981-08-26 Sandoz Ltd New pleuromutilin derivatives, their production and use
US5041534A (en) * 1983-03-22 1991-08-20 Merrell Dow Pharmaceuticals Process for preparing antibiotic L 17054
FR2551442B1 (fr) * 1983-09-05 1987-04-30 Centre Nat Rech Scient Nouveaux derives furaniques, leur preparation et leur application
US5077398A (en) * 1986-11-18 1991-12-31 Merck & Co., Inc. Process for isolation of avermectin B1 components with improved purity and subsequent isolaton of B2 components
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
AT400674B (de) * 1991-07-24 1996-02-26 Biochemie Gmbh Pharmazeutische pleuromutilin-zubereitung
JP3816570B2 (ja) * 1996-02-16 2006-08-30 塩水港精糖株式会社 アシル化剤
GB9614017D0 (en) * 1996-07-04 1996-09-04 Biochemie Gmbh Organic compounds
UY25225A1 (es) 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
ES2182703B1 (es) * 2001-06-18 2004-06-01 Consejo Superior De Investigaciones Cientificas Un procedimiento enzimatico para obtener 4-0-b-d-galactopiranosil-d-xilosa, 4-o-b-d-galactopiranosil-d-xilosa obtenida de acuerdo con el pr cedimiento, composiciones que la contienen y su uso en la evaluacion de la lactasa intestinal.
GB0218578D0 (en) * 2002-08-09 2002-09-18 Glaxo Group Ltd Novel method
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
ES2335284T3 (es) 2003-09-03 2010-03-24 Glaxo Group Limited Nuevo procedimiento para preparar derivados de pleuromutilina.
US6838576B1 (en) 2003-10-23 2005-01-04 3M Innovative Properties Company Process for preparing functional group-containing olefinic compounds
US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
US20060046962A1 (en) 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
GB0513058D0 (en) * 2005-06-27 2005-08-03 Sandoz Ag Organic compounds
US8173594B2 (en) * 2006-06-23 2012-05-08 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
US8084022B2 (en) 2006-06-23 2011-12-27 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
US7998927B2 (en) * 2006-06-23 2011-08-16 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
US20090326193A1 (en) * 2006-06-23 2009-12-31 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
EP1972618A1 (en) 2007-03-20 2008-09-24 Nabriva Therapeutics AG Pleuromutilin derivatives for the treatment of diseases mediated by microbes
ES2586032T3 (es) 2008-03-28 2016-10-11 Hale Biopharma Ventures, Llc Administración de composiciones de benzodiazepinas
US8440631B2 (en) 2008-12-22 2013-05-14 Aegis Therapeutics, Llc Compositions for drug administration
ES2683902T3 (es) 2011-06-14 2018-09-28 Hale Biopharma Ventures, Llc Administración de benzodiacepina
US20170274087A1 (en) * 2014-09-19 2017-09-28 Emory University Saccharide analogs and agents for the diagnosis and therapy of bacterial infections
JP6818019B2 (ja) 2015-06-17 2021-01-20 ナブリヴァ セラピュティクス ゲーエムベーハー レファムリンの注射可能医薬組成物

Also Published As

Publication number Publication date
RO80082B (ro) 1983-01-30
PL123850B1 (en) 1982-12-31
IT1160316B (it) 1987-03-11
AU524665B2 (en) 1982-09-30
RO84425B (ro) 1984-08-30
HU181429B (en) 1983-07-28
RO84425A (ro) 1984-06-21
FR2411205A1 (fr) 1979-07-06
GB2009738A (en) 1979-06-20
PL211492A1 (pl) 1979-11-19
JPS5498751A (en) 1979-08-03
DE2862226D1 (en) 1983-05-11
ZA786872B (en) 1980-08-27
IL56115A0 (en) 1979-03-12
RO84426A (ro) 1984-06-21
IE782421L (en) 1979-06-08
IE47533B1 (en) 1984-04-18
IL56115A (en) 1984-01-31
DK539578A (da) 1979-07-05
RO84426B (ro) 1984-08-30
LU80619A1 (fr) 1979-06-05
BE872489A (fr) 1979-06-05
EP0002588B1 (en) 1983-04-06
AT362065B (de) 1981-04-27
YU281878A (en) 1983-06-30
CA1109866A (en) 1981-09-29
US4130709A (en) 1978-12-19
RO80082A (ro) 1983-02-01
GB2009738B (en) 1982-11-10
ES475854A1 (es) 1980-05-16
CH639103A5 (fr) 1983-10-31
CS219344B2 (en) 1983-03-25
EP0002588A1 (en) 1979-06-27
GR72774B (ro) 1983-12-05
FR2411205B1 (ro) 1981-08-14
DD139858A5 (de) 1980-01-23
IT7830657A0 (it) 1978-12-06
PT68857A (en) 1979-01-01
AU4216278A (en) 1979-06-14
FI783709A7 (fi) 1979-06-09
ATA871578A (de) 1980-09-15
SU902666A3 (ru) 1982-01-30

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