CS207788B2 - Method of making the new aminoderivatives of the 3-alcyl-5/2-hydroxystyryl/isoxazoles - Google Patents

Method of making the new aminoderivatives of the 3-alcyl-5/2-hydroxystyryl/isoxazoles Download PDF

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Publication number
CS207788B2
CS207788B2 CS792882A CS288279A CS207788B2 CS 207788 B2 CS207788 B2 CS 207788B2 CS 792882 A CS792882 A CS 792882A CS 288279 A CS288279 A CS 288279A CS 207788 B2 CS207788 B2 CS 207788B2
Authority
CS
Czechoslovakia
Prior art keywords
isoxazole
styryl
methyl
acid addition
addition salt
Prior art date
Application number
CS792882A
Other languages
Czech (cs)
English (en)
Inventor
Peter C Thieme
Fritz-Frieder Frickel
Hans Theobald
Albrecht Franke
Dieter Lenke
Josef Gries
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of CS207788B2 publication Critical patent/CS207788B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS792882A 1978-04-29 1979-04-25 Method of making the new aminoderivatives of the 3-alcyl-5/2-hydroxystyryl/isoxazoles CS207788B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782818999 DE2818999A1 (de) 1978-04-29 1978-04-29 Aminoderivate von 3-alkyl-5-(2- hydroxystyryl)-isoxazolen

Publications (1)

Publication Number Publication Date
CS207788B2 true CS207788B2 (en) 1981-08-31

Family

ID=6038372

Family Applications (1)

Application Number Title Priority Date Filing Date
CS792882A CS207788B2 (en) 1978-04-29 1979-04-25 Method of making the new aminoderivatives of the 3-alcyl-5/2-hydroxystyryl/isoxazoles

Country Status (19)

Country Link
US (1) US4251539A (ja)
EP (1) EP0005192B1 (ja)
JP (1) JPS54144365A (ja)
AT (1) AT366674B (ja)
AU (1) AU522924B2 (ja)
CA (1) CA1128051A (ja)
CS (1) CS207788B2 (ja)
DD (1) DD143257A5 (ja)
DE (2) DE2818999A1 (ja)
DK (1) DK150602C (ja)
ES (1) ES480046A1 (ja)
FI (1) FI791363A (ja)
GR (1) GR68708B (ja)
HU (1) HU178989B (ja)
IE (1) IE48277B1 (ja)
IL (1) IL57088A0 (ja)
NO (1) NO791428L (ja)
YU (1) YU40994B (ja)
ZA (1) ZA792025B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2943405A1 (de) * 1979-10-26 1981-05-07 Basf Ag, 6700 Ludwigshafen Neue aminoderivate des 5-(2-hydroxystyryl)-isoxazols
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
DE69425882T2 (de) * 1993-03-29 2001-01-11 Basf Ag 1-amino-3-phenoxy-propan-derivate als modulatoren bei multi-drug resistenz
EP0814081A1 (en) 1996-06-17 1997-12-29 Eli Lilly And Company Drug resistance and multidrug resistance modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451115A (de) * 1964-09-10 1968-05-15 Ciba Geigy Verfahren zur Herstellung eines neuen Amins
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives
US3836671A (en) * 1969-02-21 1974-09-17 Ici Ltd Alkanolamine derivatives for producing beta-adrenergic blockade
BE754405A (fr) * 1969-08-05 1971-02-04 Thomae Gmbh Dr K Nouveaux beta-aryl-2-aminoalcoxystyrenes
US3624079A (en) * 1969-10-20 1971-11-30 Upjohn Co 5-(phenylstryl)-3methylisoxazoles
DE2624918A1 (de) * 1976-06-03 1977-12-15 Thomae Gmbh Dr K Arzneimittel mit antiarrhythmischer wirkung

Also Published As

Publication number Publication date
AU522924B2 (en) 1982-07-01
AT366674B (de) 1982-04-26
IL57088A0 (en) 1979-07-25
DK150602B (da) 1987-04-13
DD143257A5 (de) 1980-08-13
HU178989B (en) 1982-07-28
EP0005192B1 (de) 1981-12-30
GR68708B (ja) 1982-02-02
FI791363A (fi) 1979-10-30
JPS54144365A (en) 1979-11-10
DE2961653D1 (en) 1982-02-18
CA1128051A (en) 1982-07-20
ES480046A1 (es) 1980-09-01
DK175179A (da) 1979-10-30
AU4655779A (en) 1979-11-01
DE2818999A1 (de) 1979-11-15
ZA792025B (en) 1980-06-25
EP0005192A1 (de) 1979-11-14
YU40994B (en) 1986-10-31
JPS6320819B2 (ja) 1988-04-30
US4251539A (en) 1981-02-17
IE790857L (en) 1979-10-29
DK150602C (da) 1987-12-07
NO791428L (no) 1979-10-30
IE48277B1 (en) 1984-11-28
ATA319779A (de) 1981-09-15
YU102179A (en) 1983-02-28

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