ES480046A1 - Procedimiento para la obtencion de derivados amino de 3-al- quil-5-2-hidroxiestiril. - Google Patents

Procedimiento para la obtencion de derivados amino de 3-al- quil-5-2-hidroxiestiril.

Info

Publication number
ES480046A1
ES480046A1 ES480046A ES480046A ES480046A1 ES 480046 A1 ES480046 A1 ES 480046A1 ES 480046 A ES480046 A ES 480046A ES 480046 A ES480046 A ES 480046A ES 480046 A1 ES480046 A1 ES 480046A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
hydroxystyryl
preparation
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480046A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of ES480046A1 publication Critical patent/ES480046A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Procedimiento para la obtención de derivados amino de 3- alquil-5-(2-hidroxiestiril)-isoxazoles de la fórmula general I: **(Fórmula)** en la cual R es un átomo de hidrógeno, un radical alquilo con 1 a 8 átomos de carbono que en caso dado está sustituido por hidroxi, alcoxi con 1 hasta 3 átomos de carbono o cicloalquilo con 3 hasta 8 átomos de carbono en el anillo, un radical alquenilo o alquinilo con 2 hasta 8 átomos de carbono, un radical cicloalquilo con 3 hasta 8 átomos de carbono en el anillo, pudiendo los anillos cicloalquilo estar mono o disustituidos por un radical alquilo con 1 hasta 3 átomos de carbono, R1 es un radical alquilo con 1 hasta 3 átomos de carbono, y las sales de adición ácidas de estos compuestos.
ES480046A 1978-04-29 1979-04-27 Procedimiento para la obtencion de derivados amino de 3-al- quil-5-2-hidroxiestiril. Expired ES480046A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782818999 DE2818999A1 (de) 1978-04-29 1978-04-29 Aminoderivate von 3-alkyl-5-(2- hydroxystyryl)-isoxazolen

Publications (1)

Publication Number Publication Date
ES480046A1 true ES480046A1 (es) 1980-09-01

Family

ID=6038372

Family Applications (1)

Application Number Title Priority Date Filing Date
ES480046A Expired ES480046A1 (es) 1978-04-29 1979-04-27 Procedimiento para la obtencion de derivados amino de 3-al- quil-5-2-hidroxiestiril.

Country Status (19)

Country Link
US (1) US4251539A (es)
EP (1) EP0005192B1 (es)
JP (1) JPS54144365A (es)
AT (1) AT366674B (es)
AU (1) AU522924B2 (es)
CA (1) CA1128051A (es)
CS (1) CS207788B2 (es)
DD (1) DD143257A5 (es)
DE (2) DE2818999A1 (es)
DK (1) DK150602C (es)
ES (1) ES480046A1 (es)
FI (1) FI791363A (es)
GR (1) GR68708B (es)
HU (1) HU178989B (es)
IE (1) IE48277B1 (es)
IL (1) IL57088A0 (es)
NO (1) NO791428L (es)
YU (1) YU40994B (es)
ZA (1) ZA792025B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2943405A1 (de) * 1979-10-26 1981-05-07 Basf Ag, 6700 Ludwigshafen Neue aminoderivate des 5-(2-hydroxystyryl)-isoxazols
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
DE69425882T2 (de) * 1993-03-29 2001-01-11 Basf Ag 1-amino-3-phenoxy-propan-derivate als modulatoren bei multi-drug resistenz
EP0814081A1 (en) 1996-06-17 1997-12-29 Eli Lilly And Company Drug resistance and multidrug resistance modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451115A (de) * 1964-09-10 1968-05-15 Ciba Geigy Verfahren zur Herstellung eines neuen Amins
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives
US3836671A (en) * 1969-02-21 1974-09-17 Ici Ltd Alkanolamine derivatives for producing beta-adrenergic blockade
BE754405A (fr) * 1969-08-05 1971-02-04 Thomae Gmbh Dr K Nouveaux beta-aryl-2-aminoalcoxystyrenes
US3624079A (en) * 1969-10-20 1971-11-30 Upjohn Co 5-(phenylstryl)-3methylisoxazoles
DE2624918A1 (de) * 1976-06-03 1977-12-15 Thomae Gmbh Dr K Arzneimittel mit antiarrhythmischer wirkung

Also Published As

Publication number Publication date
AU522924B2 (en) 1982-07-01
AT366674B (de) 1982-04-26
IL57088A0 (en) 1979-07-25
DK150602B (da) 1987-04-13
DD143257A5 (de) 1980-08-13
HU178989B (en) 1982-07-28
EP0005192B1 (de) 1981-12-30
GR68708B (es) 1982-02-02
FI791363A (fi) 1979-10-30
JPS54144365A (en) 1979-11-10
DE2961653D1 (en) 1982-02-18
CA1128051A (en) 1982-07-20
DK175179A (da) 1979-10-30
AU4655779A (en) 1979-11-01
DE2818999A1 (de) 1979-11-15
ZA792025B (en) 1980-06-25
EP0005192A1 (de) 1979-11-14
YU40994B (en) 1986-10-31
JPS6320819B2 (es) 1988-04-30
US4251539A (en) 1981-02-17
IE790857L (en) 1979-10-29
DK150602C (da) 1987-12-07
NO791428L (no) 1979-10-30
IE48277B1 (en) 1984-11-28
ATA319779A (de) 1981-09-15
YU102179A (en) 1983-02-28
CS207788B2 (en) 1981-08-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203