IE790237L - Benzimidazol-2-ones. - Google Patents
Benzimidazol-2-ones.Info
- Publication number
- IE790237L IE790237L IE790237A IE23779A IE790237L IE 790237 L IE790237 L IE 790237L IE 790237 A IE790237 A IE 790237A IE 23779 A IE23779 A IE 23779A IE 790237 L IE790237 L IE 790237L
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- receptor
- formula
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention relates to etherified hydroxy-benzodiheterocyclic compounds of the formula <IMAGE> in which alk denotes vicinal alkylene containing 2 or 3 carbon atoms and acid addition salts thereof and processes for the manufacture of these compounds and also pharmaceutical formulations containing compounds of the formula or pharmaceutically acceptable acid addition salts. These new compounds display valuable pharmacological properties, in particular strong and long- lasting, cardio-selective beta-receptor- blocking activity and also alpha- receptor-blocking activity and can be used, e.g., for the treatment of disorders of the cardiac rhythme and coronary heart diseases and also as hypotensive agents.
[EP0003758A1]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH145078 | 1978-02-09 | ||
CH559478 | 1978-05-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
IE790237L true IE790237L (en) | 1979-08-09 |
Family
ID=25687688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE790237A IE790237L (en) | 1978-02-09 | 1979-02-08 | Benzimidazol-2-ones. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0003758A1 (en) |
JP (1) | JPS54117475A (en) |
AU (1) | AU4410279A (en) |
DD (1) | DD141926A6 (en) |
DK (1) | DK52179A (en) |
FI (1) | FI790397A (en) |
GB (1) | GB2014146A (en) |
GR (1) | GR72461B (en) |
IE (1) | IE790237L (en) |
IL (1) | IL56617A0 (en) |
NO (1) | NO790409L (en) |
PL (1) | PL213252A3 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2905877A1 (en) * | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | NEW AMINOPROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
PT71175A (en) | 1979-05-04 | 1980-05-01 | Continental Pharma | PROCESS FOR PREPARING BENZIMIDAZOLE DERIVATIVES |
WO1995004047A1 (en) * | 1993-07-31 | 1995-02-09 | Smithkline Beecham Plc | 2-benzoheterocyclyloxy or thiopropanolamine derivatives with adreno receptor agonist activity |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
CH476719A (en) * | 1963-07-30 | 1969-08-15 | Ici Ltd | Process for the preparation of new heterocyclic derivatives |
CH624395A5 (en) * | 1976-01-08 | 1981-07-31 | Ciba Geigy Ag | |
GB1595316A (en) * | 1977-05-03 | 1981-08-12 | Roche Products Ltd | 4-(3-amino-2-hydroxy-propoxy)-benzimidazole derivatives and pharmaceutical compositions containing them |
NZ187066A (en) * | 1977-05-03 | 1981-02-11 | Hoffmann La Roche | 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones) |
-
1979
- 1979-01-31 EP EP79100273A patent/EP0003758A1/en not_active Withdrawn
- 1979-02-07 PL PL21325279A patent/PL213252A3/xx unknown
- 1979-02-07 IL IL56617A patent/IL56617A0/en unknown
- 1979-02-07 FI FI790397A patent/FI790397A/en unknown
- 1979-02-07 GR GR58288A patent/GR72461B/el unknown
- 1979-02-08 AU AU44102/79A patent/AU4410279A/en not_active Abandoned
- 1979-02-08 IE IE790237A patent/IE790237L/en unknown
- 1979-02-08 NO NO790409A patent/NO790409L/en unknown
- 1979-02-08 DD DD79210909A patent/DD141926A6/en unknown
- 1979-02-08 GB GB7904509A patent/GB2014146A/en not_active Withdrawn
- 1979-02-08 DK DK52179A patent/DK52179A/en unknown
- 1979-02-09 JP JP1346479A patent/JPS54117475A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
PL213252A3 (en) | 1980-03-24 |
JPS54117475A (en) | 1979-09-12 |
IL56617A0 (en) | 1979-05-31 |
GR72461B (en) | 1983-11-10 |
GB2014146A (en) | 1979-08-22 |
EP0003758A1 (en) | 1979-09-05 |
DK52179A (en) | 1979-08-10 |
DD141926A6 (en) | 1980-05-28 |
FI790397A (en) | 1979-08-10 |
AU4410279A (en) | 1979-08-16 |
NO790409L (en) | 1979-08-10 |
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