CS207617B2 - Method of making the new derivatives of 5,11-dihydro-6h-pyrido-2,3-b 1,4 benzodiazepin-6-one - Google Patents

Method of making the new derivatives of 5,11-dihydro-6h-pyrido-2,3-b 1,4 benzodiazepin-6-one Download PDF

Info

Publication number
CS207617B2
CS207617B2 CS783471A CS347178A CS207617B2 CS 207617 B2 CS207617 B2 CS 207617B2 CS 783471 A CS783471 A CS 783471A CS 347178 A CS347178 A CS 347178A CS 207617 B2 CS207617 B2 CS 207617B2
Authority
CS
Czechoslovakia
Prior art keywords
carbon atoms
methyl
dihydro
pyrido
benzodiazepin
Prior art date
Application number
CS783471A
Other languages
Czech (cs)
English (en)
Inventor
Guenter Schmidt
Matyas Leitold
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Priority to CS798701A priority Critical patent/CS207618B2/cs
Publication of CS207617B2 publication Critical patent/CS207617B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS783471A 1977-05-31 1978-05-29 Method of making the new derivatives of 5,11-dihydro-6h-pyrido-2,3-b 1,4 benzodiazepin-6-one CS207617B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS798701A CS207618B2 (cs) 1977-05-31 1979-12-12 Způsob výroby nových derivátů 5,ll-dihydro-6H-pyrido[2,3-b] [1,4]- benzodiazepin-B-onu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772724434 DE2724434A1 (de) 1977-05-31 1977-05-31 Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
CS207617B2 true CS207617B2 (en) 1981-08-31

Family

ID=6010263

Family Applications (1)

Application Number Title Priority Date Filing Date
CS783471A CS207617B2 (en) 1977-05-31 1978-05-29 Method of making the new derivatives of 5,11-dihydro-6h-pyrido-2,3-b 1,4 benzodiazepin-6-one

Country Status (31)

Country Link
US (1) US4213984A (fi)
JP (1) JPS543096A (fi)
AT (1) AT361491B (fi)
AU (1) AU516893B2 (fi)
BE (1) BE867638A (fi)
BG (2) BG28711A3 (fi)
CA (1) CA1109064A (fi)
CH (1) CH637652A5 (fi)
CS (1) CS207617B2 (fi)
DD (1) DD137106A5 (fi)
DE (1) DE2724434A1 (fi)
DK (1) DK239578A (fi)
ES (2) ES470270A1 (fi)
FI (1) FI63232C (fi)
FR (1) FR2392993A1 (fi)
GB (1) GB1571781A (fi)
GR (1) GR66164B (fi)
HK (1) HK11182A (fi)
HU (1) HU180999B (fi)
IE (1) IE46907B1 (fi)
IL (1) IL54813A (fi)
MY (1) MY8200242A (fi)
NL (1) NL7805847A (fi)
NO (1) NO149313C (fi)
NZ (1) NZ187426A (fi)
PH (1) PH14609A (fi)
PL (2) PL113628B1 (fi)
PT (1) PT68112A (fi)
SE (1) SE7806288L (fi)
SU (1) SU772484A3 (fi)
ZA (1) ZA783084B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3204403A1 (de) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3204401A1 (de) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820345A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage
AU2005263577C1 (en) 2004-07-16 2010-08-26 Proteosys Ag Muscarinic antagonists with PARP and SiR modulating activity as cytoprotective agents
EP2379080A1 (en) 2009-01-13 2011-10-26 ProteoSys AG Pirenzepine as otoprotective agent
CN103242246A (zh) * 2013-05-21 2013-08-14 苏州科捷生物医药有限公司 3-位取代的n-甲基哌嗪的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel

Also Published As

Publication number Publication date
ATA367878A (de) 1980-08-15
JPS543096A (en) 1979-01-11
IE781071L (en) 1978-11-30
GB1571781A (en) 1980-07-16
GR66164B (fi) 1981-01-20
PL207191A1 (pl) 1979-07-16
FI781474A (fi) 1978-12-01
DD137106A5 (de) 1979-08-15
FI63232C (fi) 1983-05-10
NO781878L (no) 1978-12-01
SE7806288L (sv) 1978-12-01
NO149313B (no) 1983-12-19
NL7805847A (nl) 1978-12-04
AU516893B2 (en) 1981-06-25
FR2392993A1 (fr) 1978-12-29
NO149313C (no) 1984-03-28
BG26949A4 (fi) 1979-07-12
PL112911B1 (en) 1980-11-29
US4213984A (en) 1980-07-22
PH14609A (en) 1981-10-02
BG28711A3 (en) 1980-06-16
ZA783084B (en) 1980-02-27
AT361491B (de) 1981-03-10
AU3662278A (en) 1979-12-06
PT68112A (de) 1978-06-01
ES473441A1 (es) 1979-05-01
IL54813A0 (en) 1978-07-31
CA1109064A (en) 1981-09-15
SU772484A3 (ru) 1980-10-15
BE867638A (fr) 1978-11-30
DK239578A (da) 1978-12-01
FI63232B (fi) 1983-01-31
IE46907B1 (en) 1983-11-02
FR2392993B1 (fi) 1981-06-26
ES470270A1 (es) 1979-01-01
HU180999B (en) 1983-05-30
IL54813A (en) 1982-02-28
MY8200242A (en) 1982-12-31
PL214169A1 (fi) 1979-11-05
NZ187426A (en) 1981-10-19
HK11182A (en) 1982-03-19
PL113628B1 (en) 1980-12-31
CH637652A5 (de) 1983-08-15
DE2724434A1 (de) 1979-02-22

Similar Documents

Publication Publication Date Title
KR0138529B1 (ko) 카르보스티릴 유도체
US4675319A (en) Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use
US4788191A (en) 1,3-dithiolano-, 1,4-dithiino- and 1,4-dithiepino[2,3-C]pyrrole derivatives, their production and use
US4500525A (en) Pharmacologically active pyrazolo/4,3-c/pyridines
EP1891067B1 (en) Androgen receptor modulator compounds and methods
US4556653A (en) Pyrido[1,5]benzodiazepinone derivatives and pharmacological activities thereof
JPH05222048A (ja) 水溶性カンプトテシン誘導体
CS207617B2 (en) Method of making the new derivatives of 5,11-dihydro-6h-pyrido-2,3-b 1,4 benzodiazepin-6-one
AU2003292320A1 (en) Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same
US3705907A (en) 4-(2-hydroxy)-3-aminopropoxy)-indole derivatives
EP0198456A2 (en) 1,7-Naphthyridine derivatives and medicinal preparations containing same
CS202600B2 (en) Process for preparing new derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-one
US4596809A (en) Substituted 1,8-naphthyridinones, useful as anti-allergic agents
CS207619B2 (en) Method of making the new derivatives of 5,11-dihydro-6h-pyrido 2,3-b 1,4 benzodiazepin-6-on
SU1644717A3 (ru) Способ получени производных N-(4-пиперидинил)-бициклического конденсированного 2-имидазоламина, их фармацевтически приемлемых солей присоединени кислот или их стереоизомеров
SU936809A3 (ru) Способ получени серосодержащих производных изохинолина
JPH10505333A (ja) イミダゾピリジン−アゾリジノン
CA1337201C (en) 4,5,6,7-tetrahydroisothiazolo [4,5-c] pyridine derivatives
JPH10505332A (ja) アシルイミダゾピリジン
PT92494B (pt) Processo para a preparacao de novos derivados do indol
CS207618B2 (cs) Způsob výroby nových derivátů 5,ll-dihydro-6H-pyrido[2,3-b] [1,4]- benzodiazepin-B-onu
EP0090275A2 (en) Isoxazole (5,4-b) pyridines
KR810000811B1 (ko) 11-위치 치환된 5,11-디하이드로-6H-피리도[2,3-b][1,4] 벤조디아제핀-6-온의 제조방법
US3823153A (en) 2-substituted-3a,4,5,6,7,7a-hexahydro-3a-hydroxybenzothiazolium halides
CS207620B2 (cs) Způsob výroby nových derivátů 5,11-dihydro-BH-pyrido [ 2,3-b ] [ 1,4 ] - benzodiazepin-6-onu