ES473441A1 - Procedimiento para la preparacion de nuevos derivados de 5,-11-dihidro-6h-pirido (2,3-b)(1,4-benzodiazepin-6-ona). - Google Patents

Procedimiento para la preparacion de nuevos derivados de 5,-11-dihidro-6h-pirido (2,3-b)(1,4-benzodiazepin-6-ona).

Info

Publication number
ES473441A1
ES473441A1 ES473441A ES473441A ES473441A1 ES 473441 A1 ES473441 A1 ES 473441A1 ES 473441 A ES473441 A ES 473441A ES 473441 A ES473441 A ES 473441A ES 473441 A1 ES473441 A1 ES 473441A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
methyl
ethyl
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES473441A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES473441A1 publication Critical patent/ES473441A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedimiento para la preparación de nuevos derivados de 5,11-dihidro-6H-pirido[2,3-b][1,4]benzodiazepin-6-ona de la fórmula general: **(Fórmula)** en la que R1 significa un grupo alcohilo de cadena recta o ramificada, con 3 a 12 átomos de carbono, un radical hidrocarbonado alifático insaturado, de cadena recta o ramificada, con 3 a 20 átomos de carbono y 1 a 3 dobles enlaces y7o un enlace triple, un grupo fenilalcohilo con 2 a 4 átomos de carbono en el radical alcohileno de cadena recta o ramificado.
ES473441A 1977-05-31 1978-09-18 Procedimiento para la preparacion de nuevos derivados de 5,-11-dihidro-6h-pirido (2,3-b)(1,4-benzodiazepin-6-ona). Expired ES473441A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772724434 DE2724434A1 (de) 1977-05-31 1977-05-31 Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES473441A1 true ES473441A1 (es) 1979-05-01

Family

ID=6010263

Family Applications (2)

Application Number Title Priority Date Filing Date
ES470270A Expired ES470270A1 (es) 1977-05-31 1978-05-29 Procedimiento para la preparacion de nuevos derivados de 5, 11 - dihidro-6h-pirido(2,3-b) (1,4) benzodiaxepin-6-ona
ES473441A Expired ES473441A1 (es) 1977-05-31 1978-09-18 Procedimiento para la preparacion de nuevos derivados de 5,-11-dihidro-6h-pirido (2,3-b)(1,4-benzodiazepin-6-ona).

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES470270A Expired ES470270A1 (es) 1977-05-31 1978-05-29 Procedimiento para la preparacion de nuevos derivados de 5, 11 - dihidro-6h-pirido(2,3-b) (1,4) benzodiaxepin-6-ona

Country Status (31)

Country Link
US (1) US4213984A (es)
JP (1) JPS543096A (es)
AT (1) AT361491B (es)
AU (1) AU516893B2 (es)
BE (1) BE867638A (es)
BG (2) BG26949A4 (es)
CA (1) CA1109064A (es)
CH (1) CH637652A5 (es)
CS (1) CS207617B2 (es)
DD (1) DD137106A5 (es)
DE (1) DE2724434A1 (es)
DK (1) DK239578A (es)
ES (2) ES470270A1 (es)
FI (1) FI63232C (es)
FR (1) FR2392993A1 (es)
GB (1) GB1571781A (es)
GR (1) GR66164B (es)
HK (1) HK11182A (es)
HU (1) HU180999B (es)
IE (1) IE46907B1 (es)
IL (1) IL54813A (es)
MY (1) MY8200242A (es)
NL (1) NL7805847A (es)
NO (1) NO149313C (es)
NZ (1) NZ187426A (es)
PH (1) PH14609A (es)
PL (2) PL112911B1 (es)
PT (1) PT68112A (es)
SE (1) SE7806288L (es)
SU (1) SU772484A3 (es)
ZA (1) ZA783084B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3204401A1 (de) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3204403A1 (de) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820345A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage
CA2573674A1 (en) 2004-07-16 2006-01-26 Proteosys Ag Muscarinic antagonists with parp and sir modulating activity as agents for inflammatory diseases
EP2379080A1 (en) 2009-01-13 2011-10-26 ProteoSys AG Pirenzepine as otoprotective agent
CN103242246A (zh) * 2013-05-21 2013-08-14 苏州科捷生物医药有限公司 3-位取代的n-甲基哌嗪的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel

Also Published As

Publication number Publication date
BE867638A (fr) 1978-11-30
FI63232C (fi) 1983-05-10
BG28711A3 (en) 1980-06-16
ZA783084B (en) 1980-02-27
FR2392993A1 (fr) 1978-12-29
SU772484A3 (ru) 1980-10-15
CH637652A5 (de) 1983-08-15
ES470270A1 (es) 1979-01-01
HU180999B (en) 1983-05-30
AU3662278A (en) 1979-12-06
MY8200242A (en) 1982-12-31
PL214169A1 (es) 1979-11-05
FR2392993B1 (es) 1981-06-26
GR66164B (es) 1981-01-20
PT68112A (de) 1978-06-01
DD137106A5 (de) 1979-08-15
PL112911B1 (en) 1980-11-29
NL7805847A (nl) 1978-12-04
ATA367878A (de) 1980-08-15
SE7806288L (sv) 1978-12-01
PL207191A1 (pl) 1979-07-16
AU516893B2 (en) 1981-06-25
JPS543096A (en) 1979-01-11
US4213984A (en) 1980-07-22
BG26949A4 (bg) 1979-07-12
NO149313C (no) 1984-03-28
NZ187426A (en) 1981-10-19
AT361491B (de) 1981-03-10
HK11182A (en) 1982-03-19
IE781071L (en) 1978-11-30
DK239578A (da) 1978-12-01
IL54813A (en) 1982-02-28
CA1109064A (en) 1981-09-15
FI63232B (fi) 1983-01-31
DE2724434A1 (de) 1979-02-22
CS207617B2 (en) 1981-08-31
PL113628B1 (en) 1980-12-31
GB1571781A (en) 1980-07-16
IL54813A0 (en) 1978-07-31
PH14609A (en) 1981-10-02
NO149313B (no) 1983-12-19
FI781474A (fi) 1978-12-01
NO781878L (no) 1978-12-01
IE46907B1 (en) 1983-11-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103