IL54813A - 11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL54813A
IL54813A IL54813A IL5481378A IL54813A IL 54813 A IL54813 A IL 54813A IL 54813 A IL54813 A IL 54813A IL 5481378 A IL5481378 A IL 5481378A IL 54813 A IL54813 A IL 54813A
Authority
IL
Israel
Prior art keywords
benzodiazepin
pyrido
dihydro
acetyl
derivatives
Prior art date
Application number
IL54813A
Other versions
IL54813A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL54813A0 publication Critical patent/IL54813A0/en
Publication of IL54813A publication Critical patent/IL54813A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL54813A 1977-05-31 1978-05-30 11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them IL54813A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772724434 DE2724434A1 (en) 1977-05-31 1977-05-31 NEW, 11-POSITION SUBSTITUTED 5,11-DIHYDRO-6H-PYRIDO SQUARE CLAMP ON 2.3-B SQUARE CLAMP ON SQUARE CLAMP ON 1.4 SQUARED CLAMP ON BENZODIAZEPIN-6-ONE, METHOD FOR THEIR PRODUCTION AND THESE CONNECTIONS DRUG

Publications (2)

Publication Number Publication Date
IL54813A0 IL54813A0 (en) 1978-07-31
IL54813A true IL54813A (en) 1982-02-28

Family

ID=6010263

Family Applications (1)

Application Number Title Priority Date Filing Date
IL54813A IL54813A (en) 1977-05-31 1978-05-30 11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them

Country Status (31)

Country Link
US (1) US4213984A (en)
JP (1) JPS543096A (en)
AT (1) AT361491B (en)
AU (1) AU516893B2 (en)
BE (1) BE867638A (en)
BG (2) BG26949A4 (en)
CA (1) CA1109064A (en)
CH (1) CH637652A5 (en)
CS (1) CS207617B2 (en)
DD (1) DD137106A5 (en)
DE (1) DE2724434A1 (en)
DK (1) DK239578A (en)
ES (2) ES470270A1 (en)
FI (1) FI63232C (en)
FR (1) FR2392993A1 (en)
GB (1) GB1571781A (en)
GR (1) GR66164B (en)
HK (1) HK11182A (en)
HU (1) HU180999B (en)
IE (1) IE46907B1 (en)
IL (1) IL54813A (en)
MY (1) MY8200242A (en)
NL (1) NL7805847A (en)
NO (1) NO149313C (en)
NZ (1) NZ187426A (en)
PH (1) PH14609A (en)
PL (2) PL112911B1 (en)
PT (1) PT68112A (en)
SE (1) SE7806288L (en)
SU (1) SU772484A3 (en)
ZA (1) ZA783084B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
IT1130973B (en) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C PROCESS FOR THE PREPARATION OF DERIVATIVES OF 5,11-DI-HYDRO-6H-PYRID (2,3-B) (1,4) -BENZODIAZEPIN-6-ONE, FINAL AND INTERMEDIATE DERIVATIVES OF SYNTHESIS IN THIS WAY OBTAINED
DE3204403A1 (en) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach NEW PYRIDOBENZODIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3204401A1 (en) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach PYRIDOBENZODIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
IT1212742B (en) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa DIBENZO DERIVATIVES [1,4] PYRID DIAZEPINONIC [1,4] BENZODIAZEPINONIC, PYRID [1,5] BENZODIAZEPINONIC AND THEIR PHARMACOLOGICAL ACTIVITY
DE3726908A1 (en) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS
DE3820345A1 (en) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING THESE COMPOUNDS
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage
CA2573673A1 (en) 2004-07-16 2006-01-26 Proteosys Ag Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents
EP2379080A1 (en) 2009-01-13 2011-10-26 ProteoSys AG Pirenzepine as otoprotective agent
CN103242246A (en) * 2013-05-21 2013-08-14 苏州科捷生物医药有限公司 Synthetic method of 3-substituted N-methyl piperazine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (en) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-dihydro-6H-pyrido [2,3-b] [1,4] benzodiazepin-6-one derivatives and drugs

Also Published As

Publication number Publication date
AU516893B2 (en) 1981-06-25
ATA367878A (en) 1980-08-15
NO149313C (en) 1984-03-28
AU3662278A (en) 1979-12-06
JPS543096A (en) 1979-01-11
FI63232C (en) 1983-05-10
MY8200242A (en) 1982-12-31
PL214169A1 (en) 1979-11-05
NO149313B (en) 1983-12-19
DK239578A (en) 1978-12-01
FI63232B (en) 1983-01-31
CH637652A5 (en) 1983-08-15
IE781071L (en) 1978-11-30
BE867638A (en) 1978-11-30
NO781878L (en) 1978-12-01
AT361491B (en) 1981-03-10
FR2392993B1 (en) 1981-06-26
SU772484A3 (en) 1980-10-15
PL207191A1 (en) 1979-07-16
HK11182A (en) 1982-03-19
US4213984A (en) 1980-07-22
DD137106A5 (en) 1979-08-15
DE2724434A1 (en) 1979-02-22
FR2392993A1 (en) 1978-12-29
BG28711A3 (en) 1980-06-16
GR66164B (en) 1981-01-20
PL113628B1 (en) 1980-12-31
NL7805847A (en) 1978-12-04
PH14609A (en) 1981-10-02
PT68112A (en) 1978-06-01
CS207617B2 (en) 1981-08-31
ES470270A1 (en) 1979-01-01
HU180999B (en) 1983-05-30
NZ187426A (en) 1981-10-19
IE46907B1 (en) 1983-11-02
PL112911B1 (en) 1980-11-29
ZA783084B (en) 1980-02-27
BG26949A4 (en) 1979-07-12
CA1109064A (en) 1981-09-15
FI781474A7 (en) 1978-12-01
SE7806288L (en) 1978-12-01
GB1571781A (en) 1980-07-16
IL54813A0 (en) 1978-07-31
ES473441A1 (en) 1979-05-01

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