CS199578B2 - Process for preparing new aryloxyaminobutanoles,stereoisomers thereof and non-toxic additive salts with acids - Google Patents

Process for preparing new aryloxyaminobutanoles,stereoisomers thereof and non-toxic additive salts with acids Download PDF

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Publication number
CS199578B2
CS199578B2 CS751129A CS112975A CS199578B2 CS 199578 B2 CS199578 B2 CS 199578B2 CS 751129 A CS751129 A CS 751129A CS 112975 A CS112975 A CS 112975A CS 199578 B2 CS199578 B2 CS 199578B2
Authority
CS
Czechoslovakia
Prior art keywords
compounds
general formula
formula
hydroxy
stereoisomers
Prior art date
Application number
CS751129A
Other languages
Czech (cs)
English (en)
Inventor
Kalman Harsanyi
Deszoe Korbonits
Erzsebet Molnar
Joszef Szegi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to CS774232A priority Critical patent/CS199579B2/cs
Publication of CS199578B2 publication Critical patent/CS199578B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS751129A 1974-02-20 1975-02-20 Process for preparing new aryloxyaminobutanoles,stereoisomers thereof and non-toxic additive salts with acids CS199578B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS774232A CS199579B2 (cs) 1974-02-20 1977-06-27 Způsob výroby nových aryloxyamlnobntanolů, Jejich stereoisomerů a netoxických adičních solí s kyselinami

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1449A HU169464B (de) 1974-02-20 1974-02-20

Publications (1)

Publication Number Publication Date
CS199578B2 true CS199578B2 (en) 1980-07-31

Family

ID=10994508

Family Applications (1)

Application Number Title Priority Date Filing Date
CS751129A CS199578B2 (en) 1974-02-20 1975-02-20 Process for preparing new aryloxyaminobutanoles,stereoisomers thereof and non-toxic additive salts with acids

Country Status (22)

Country Link
JP (1) JPS5929063B2 (de)
AT (1) AT339281B (de)
BE (1) BE825745A (de)
BG (2) BG26366A3 (de)
CA (1) CA1074338A (de)
CH (1) CH619684A5 (de)
CS (1) CS199578B2 (de)
DD (1) DD119414A5 (de)
DE (1) DE2506355C2 (de)
DK (1) DK141935B (de)
ES (2) ES434784A1 (de)
FI (1) FI61304C (de)
FR (1) FR2261001B1 (de)
GB (1) GB1457086A (de)
HU (1) HU169464B (de)
IL (1) IL46634A (de)
NL (1) NL182698C (de)
NO (1) NO141754C (de)
PL (2) PL99025B1 (de)
SE (1) SE433935B (de)
SU (1) SU1025327A3 (de)
YU (2) YU36916B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48309A (en) * 1974-10-25 1980-01-31 Robins Co Inc A H 1-aryloxy-4-amino-2-butanols and pharmaceutical compositions containing them
EP0097000B1 (de) * 1982-06-10 1987-09-09 Beecham Wuelfing GmbH & Co KG Amine-Derivate, diese enthaltende Zusammenstellungen und Verfahren zu ihrer Herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE368197B (de) * 1968-11-18 1974-06-24 Pfizer
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
AT305245B (de) * 1969-09-24 1973-02-12 Ici Ltd Verfahren zur Herstellung von neuen substituierten 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen

Also Published As

Publication number Publication date
NL182698C (nl) 1988-05-02
FR2261001B1 (de) 1978-07-21
HU169464B (de) 1976-11-28
FI61304C (fi) 1982-07-12
BG26366A3 (bg) 1979-03-15
SE7501801L (de) 1975-08-21
DE2506355A1 (de) 1975-08-21
JPS50117728A (de) 1975-09-16
DK60875A (de) 1975-10-20
DD119414A5 (de) 1976-04-20
BE825745A (fr) 1975-06-16
JPS5929063B2 (ja) 1984-07-18
IL46634A0 (en) 1975-04-25
ES434784A1 (es) 1977-03-16
DK141935B (da) 1980-07-21
FI750443A (de) 1975-08-21
NL7501951A (nl) 1975-08-22
ATA114075A (de) 1977-02-15
SU1025327A3 (ru) 1983-06-23
YU37116B (en) 1984-08-31
SE433935B (sv) 1984-06-25
YU36916B (en) 1984-08-31
FI61304B (fi) 1982-03-31
PL99025B1 (pl) 1978-06-30
DK141935C (de) 1980-12-08
AT339281B (de) 1977-10-10
YU167681A (en) 1983-04-27
BG26367A4 (bg) 1979-03-15
GB1457086A (en) 1976-12-01
NO750566L (de) 1975-08-21
YU37375A (en) 1982-06-18
PL99023B1 (pl) 1978-06-30
DE2506355C2 (de) 1983-10-06
CA1074338A (en) 1980-03-25
ES453326A1 (es) 1977-11-16
CH619684A5 (en) 1980-10-15
NO141754B (no) 1980-01-28
FR2261001A1 (de) 1975-09-12
NO141754C (no) 1980-05-07
IL46634A (en) 1979-01-31

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