CR20170040A - Anticuerpos anti proteína similar a angiopoyetina 4 y métodos de uso - Google Patents

Anticuerpos anti proteína similar a angiopoyetina 4 y métodos de uso

Info

Publication number
CR20170040A
CR20170040A CR20170040A CR20170040A CR20170040A CR 20170040 A CR20170040 A CR 20170040A CR 20170040 A CR20170040 A CR 20170040A CR 20170040 A CR20170040 A CR 20170040A CR 20170040 A CR20170040 A CR 20170040A
Authority
CR
Costa Rica
Prior art keywords
angiopoyetina
methods
antibodies anti
protein similar
anti protein
Prior art date
Application number
CR20170040A
Other languages
English (en)
Spanish (es)
Inventor
John Trauger
Andrei Igorevich Voznesensky
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CR20170040A publication Critical patent/CR20170040A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CR20170040A 2014-08-07 2015-08-06 Anticuerpos anti proteína similar a angiopoyetina 4 y métodos de uso CR20170040A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462034409P 2014-08-07 2014-08-07
PCT/IB2015/055986 WO2016020880A2 (en) 2014-08-07 2015-08-06 Angiopoietin-like 4 antibodies and methods of use

Publications (1)

Publication Number Publication Date
CR20170040A true CR20170040A (es) 2017-04-28

Family

ID=53836146

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20170040A CR20170040A (es) 2014-08-07 2015-08-06 Anticuerpos anti proteína similar a angiopoyetina 4 y métodos de uso

Country Status (31)

Country Link
US (5) US9771417B2 (cg-RX-API-DMAC7.html)
EP (2) EP3177642B1 (cg-RX-API-DMAC7.html)
JP (4) JP6649358B2 (cg-RX-API-DMAC7.html)
KR (2) KR102659872B1 (cg-RX-API-DMAC7.html)
CN (1) CN107148428B (cg-RX-API-DMAC7.html)
AP (1) AP2017009721A0 (cg-RX-API-DMAC7.html)
AR (1) AR101486A1 (cg-RX-API-DMAC7.html)
AU (1) AU2015300685B2 (cg-RX-API-DMAC7.html)
BR (1) BR112017002173B1 (cg-RX-API-DMAC7.html)
CL (1) CL2017000212A1 (cg-RX-API-DMAC7.html)
CO (1) CO2017001087A2 (cg-RX-API-DMAC7.html)
CR (1) CR20170040A (cg-RX-API-DMAC7.html)
CU (1) CU24453B1 (cg-RX-API-DMAC7.html)
DK (1) DK3177642T3 (cg-RX-API-DMAC7.html)
EA (1) EA201790336A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP17013904A (cg-RX-API-DMAC7.html)
ES (1) ES2906216T3 (cg-RX-API-DMAC7.html)
IL (1) IL250289B2 (cg-RX-API-DMAC7.html)
JO (1) JO3565B1 (cg-RX-API-DMAC7.html)
MA (1) MA40512A (cg-RX-API-DMAC7.html)
MX (2) MX390418B (cg-RX-API-DMAC7.html)
NZ (1) NZ728425A (cg-RX-API-DMAC7.html)
PE (1) PE20170287A1 (cg-RX-API-DMAC7.html)
PH (1) PH12017500156A1 (cg-RX-API-DMAC7.html)
PL (1) PL3177642T3 (cg-RX-API-DMAC7.html)
PT (1) PT3177642T (cg-RX-API-DMAC7.html)
SG (2) SG10201805646WA (cg-RX-API-DMAC7.html)
TN (1) TN2017000019A1 (cg-RX-API-DMAC7.html)
TW (1) TWI675043B (cg-RX-API-DMAC7.html)
UY (1) UY36262A (cg-RX-API-DMAC7.html)
WO (1) WO2016020880A2 (cg-RX-API-DMAC7.html)

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Publication number Priority date Publication date Assignee Title
AP2017009721A0 (en) 2014-08-07 2017-01-31 Novartis Ag Angiopoietin-like 4 antibodies and methods of use
EP3194437B1 (en) 2014-08-07 2021-01-20 Novartis AG Angiopoietin-like 4 (angptl4) antibodies and methods of use
GB2569144B (en) * 2017-12-06 2021-06-16 Proimmune Ltd Method for screening the activity of mutated expressed polypeptides
US11787857B2 (en) * 2018-02-02 2023-10-17 Bio-Techne Corporation Compounds that modulate the interaction of VISTA and VSIG3 and methods of making and using
CA3134785A1 (en) * 2019-03-26 2020-10-01 Janssen Pharmaceutica Nv Antibodies to pyroglutamate amyloid-.beta. and uses thereof
WO2023175022A1 (en) * 2022-03-16 2023-09-21 INSERM (Institut National de la Santé et de la Recherche Médicale) New method to treat infectious diseases
PE20250005A1 (es) * 2022-05-02 2025-01-07 Novo Nordisk As Nuevos anticuerpos anti-angptl3 adecuados para composiciones de concentracion alta y administracion subcutanea
WO2025166073A1 (en) * 2024-01-31 2025-08-07 Alector Llc Compositions comprising anti-sortilin antibodies and uses thereof

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