CR10073A - Componentes de la matriz extracelular para la multiplicación o diferenciación de células progenitoras hepáticas - Google Patents

Componentes de la matriz extracelular para la multiplicación o diferenciación de células progenitoras hepáticas

Info

Publication number
CR10073A
CR10073A CR10073A CR10073A CR10073A CR 10073 A CR10073 A CR 10073A CR 10073 A CR10073 A CR 10073A CR 10073 A CR10073 A CR 10073A CR 10073 A CR10073 A CR 10073A
Authority
CR
Costa Rica
Prior art keywords
progenitating
hepatic
multiplication
differentiation
cells
Prior art date
Application number
CR10073A
Other languages
English (en)
Spanish (es)
Inventor
E Mcclelland Randal
M Reid Lola
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Publication of CR10073A publication Critical patent/CR10073A/es

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    • CCHEMISTRY; METALLURGY
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    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/067Hepatocytes
    • C12N5/0672Stem cells; Progenitor cells; Precursor cells; Oval cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/02Coculture with; Conditioned medium produced by embryonic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/03Coculture with; Conditioned medium produced by non-embryonic pluripotent stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/14Coculture with; Conditioned medium produced by hepatocytes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/52Fibronectin; Laminin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
CR10073A 2005-11-16 2008-06-16 Componentes de la matriz extracelular para la multiplicación o diferenciación de células progenitoras hepáticas CR10073A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73687305P 2005-11-16 2005-11-16

Publications (1)

Publication Number Publication Date
CR10073A true CR10073A (es) 2008-10-10

Family

ID=38049393

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10073A CR10073A (es) 2005-11-16 2008-06-16 Componentes de la matriz extracelular para la multiplicación o diferenciación de células progenitoras hepáticas

Country Status (13)

Country Link
US (2) US20070155009A1 (https=)
EP (1) EP1954804A4 (https=)
JP (1) JP2009515558A (https=)
KR (1) KR20080097985A (https=)
CN (1) CN101384705A (https=)
AU (1) AU2006315163A1 (https=)
BR (1) BRPI0618724A2 (https=)
CA (1) CA2630355A1 (https=)
CR (1) CR10073A (https=)
IL (1) IL191533A0 (https=)
RU (1) RU2008124158A (https=)
TW (1) TW200730627A (https=)
WO (1) WO2007059501A2 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020045260A1 (en) * 2000-10-17 2002-04-18 Shih-Chieh Hung Method of isolating mesenchymal stem cells
US8084023B2 (en) 2007-01-22 2011-12-27 The Board Of Trustees Of The University Of Arkansas Maintenance and propagation of mesenchymal stem cells
WO2008109659A2 (en) * 2007-03-06 2008-09-12 University Of North Carolina At Chapel Hill Complexes of hyaluronans, other matrix components, hormones and growth factors for maintenance, expansion and/or differentiation of cells
CA2727535A1 (en) * 2007-06-15 2008-12-24 University Of North Carolina At Chapel Hill Paracrine signals from mesenchymal feeder cells and regulating expansion and differentiation of hepatic progenitors using same
JP2010534065A (ja) * 2007-07-20 2010-11-04 セルアーティス アーベー ヒト胚盤胞幹細胞に、胚体内胚葉(DE‐hep)を介して由来する新規な肝細胞の集団
US8372643B2 (en) * 2007-12-06 2013-02-12 Agency For Science, Technology And Research Method for extracellular matrix mediated differentiation and proliferation of stem cells
ES2862623T3 (es) 2008-05-22 2021-10-07 Vesta Therapeutics Inc Método de diferenciación de células progenitoras de mamíferos en células pancreáticas de los islotes productoras de insulina
US8298584B2 (en) * 2008-12-30 2012-10-30 Collagen Matrix, Inc. Biopolymeric membrane for wound protection and repair
US20100227393A1 (en) * 2009-03-06 2010-09-09 Eric Lagasse Liver stem cells: isolation of hepatic progenitor cells from the human gall bladder
CN105456292B (zh) * 2009-10-30 2019-03-26 北卡罗来纳大学教堂山分校 来自肝外胆管树的专能干细胞及其分离方法
WO2011077894A1 (ja) * 2009-12-25 2011-06-30 Scivax株式会社 スフェロイド形成促進方法およびスフェロイド形成促進培地
JPWO2011102532A1 (ja) * 2010-02-16 2013-06-17 国立大学法人九州大学 誘導肝細胞
AU2011247984B2 (en) * 2010-05-07 2015-04-30 University Of North Carolina At Chapel Hill Method of engrafting cells from solid tissues
US9617511B2 (en) 2010-09-07 2017-04-11 The Board Of Regents Of The University Of Texas System Tissue-specific differentiation matrices and uses thereof
US9938502B2 (en) 2010-11-10 2018-04-10 Wake Forest University Health Sciences Tissue-specific extracellular matrix with or without tissue protein components for cell culture
JP6435267B2 (ja) * 2012-11-08 2018-12-05 インジェネロン インコーポレイテッド 再生細胞の培養、保存、及び投与のための培地
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
CN105189738A (zh) * 2013-04-08 2015-12-23 国立研究开发法人医药基盘·健康·营养研究所 肝母细胞样细胞的培养方法及其培养物
CN106559994A (zh) * 2014-07-16 2017-04-05 国立大学法人大阪大学 层粘连蛋白片段的细胞培养基质活性增强方法
WO2016200340A1 (en) 2015-06-12 2016-12-15 Agency For Science, Technology And Research Derivation of hepatic stem cells and mature liver cell types and uses thereof
JP6755085B2 (ja) * 2015-11-10 2020-09-16 日機装株式会社 細胞支持複合体および細胞支持複合体の製造方法
JP6605618B2 (ja) * 2015-11-10 2019-11-20 日機装株式会社 細胞支持複合体および細胞支持複合体の製造方法
RU2618989C1 (ru) * 2016-03-09 2017-05-11 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ лечения печеночной недостаточности
US20170369849A1 (en) * 2016-05-11 2017-12-28 The University Of North Carolina At Chapel Hill Compositions and methods for bioengineered tissues
KR101895669B1 (ko) * 2016-06-22 2018-09-05 한국과학기술원 접착성 헤파린과 콜라겐을 이용한 줄기세포의 배양방법
AU2017298298B2 (en) 2016-07-18 2024-03-07 President And Fellows Of Harvard College Human lymphoid tissue-on-chip
CN106434532A (zh) * 2016-12-22 2017-02-22 叶宗耀 一种培养肝细胞的培养基及其制备方法
WO2018123814A1 (ja) * 2016-12-28 2018-07-05 株式会社高研 高強度コラーゲンスポンジ
CN115948331B (zh) * 2022-10-17 2024-10-22 中国人民解放军西部战区总医院 一种从小鼠胆囊中分离获取间充质干细胞的方法
WO2025244838A1 (en) * 2024-05-21 2025-11-27 Corning Incorporated Improved collagen coatings

Family Cites Families (8)

* Cited by examiner, † Cited by third party
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US6069005A (en) * 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
WO1993003142A1 (en) * 1991-08-07 1993-02-18 Albert Einstein College Of Medicine Proliferation of hepatocyte precursors
DE4222345A1 (de) * 1992-07-08 1994-01-13 Augustinus Dr Med Bader Verfahren zum Züchten einer Zellart im Kokulturverfahren mit Leberzellen
AU779706B2 (en) 1999-01-19 2005-02-10 University Of North Carolina At Chapel Hill, The Human liver progenitors
US7456017B2 (en) * 1999-10-01 2008-11-25 University Of North Carolina At Chapel Hill Processes for clonal growth of hepatic progenitor cells
US20020187133A1 (en) * 1999-10-01 2002-12-12 Hiroshi Kubota Methods of isolating bipotent hepatic progenitor cells
HUE032238T2 (en) * 2002-03-15 2017-09-28 Univ North Carolina Chapel Hill Primitive and proximal liver stem cells
WO2008109659A2 (en) * 2007-03-06 2008-09-12 University Of North Carolina At Chapel Hill Complexes of hyaluronans, other matrix components, hormones and growth factors for maintenance, expansion and/or differentiation of cells

Also Published As

Publication number Publication date
US20070155009A1 (en) 2007-07-05
JP2009515558A (ja) 2009-04-16
EP1954804A4 (en) 2009-03-04
AU2006315163A1 (en) 2007-05-24
WO2007059501A3 (en) 2007-09-13
BRPI0618724A2 (pt) 2011-09-06
IL191533A0 (en) 2008-12-29
WO2007059501A2 (en) 2007-05-24
CA2630355A1 (en) 2007-05-24
KR20080097985A (ko) 2008-11-06
TW200730627A (en) 2007-08-16
EP1954804A2 (en) 2008-08-13
RU2008124158A (ru) 2010-01-10
US20100093077A1 (en) 2010-04-15
CN101384705A (zh) 2009-03-11

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