CO6311008A2 - Composicion farmaceutica que comprende un agente que activa las celulas t regulatorias cd4+cd25+ - Google Patents
Composicion farmaceutica que comprende un agente que activa las celulas t regulatorias cd4+cd25+Info
- Publication number
- CO6311008A2 CO6311008A2 CO10127116A CO10127116A CO6311008A2 CO 6311008 A2 CO6311008 A2 CO 6311008A2 CO 10127116 A CO10127116 A CO 10127116A CO 10127116 A CO10127116 A CO 10127116A CO 6311008 A2 CO6311008 A2 CO 6311008A2
- Authority
- CO
- Colombia
- Prior art keywords
- cells
- pharmaceutical composition
- agent
- composition understanding
- activates regulatory
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención proporciona una composición farmacéutica para tratar una enfermedad autoinmune que comprende un portador farmacéutico aceptable y un agente capaz de activar células T regulatorias CD4+CD25+ en donde la composición se va a administrar a un sujeto, cuando más cada 3 días.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0804687A GB0804687D0 (en) | 2008-03-13 | 2008-03-13 | Humanized antibody |
GB0817809A GB0817809D0 (en) | 2008-09-29 | 2008-09-29 | Agent for treating disease |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6311008A2 true CO6311008A2 (es) | 2011-08-22 |
Family
ID=40756668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO10127116A CO6311008A2 (es) | 2008-03-13 | 2010-10-13 | Composicion farmaceutica que comprende un agente que activa las celulas t regulatorias cd4+cd25+ |
Country Status (16)
Country | Link |
---|---|
US (1) | US9550831B2 (es) |
EP (1) | EP2260057B1 (es) |
JP (2) | JP5604311B2 (es) |
KR (1) | KR20100135808A (es) |
CN (1) | CN102027018A (es) |
AU (1) | AU2009224690B2 (es) |
BR (1) | BRPI0909179A2 (es) |
CA (1) | CA2717812A1 (es) |
CO (1) | CO6311008A2 (es) |
CR (1) | CR11723A (es) |
ES (1) | ES2610327T3 (es) |
IL (1) | IL207892A0 (es) |
MX (1) | MX2010010027A (es) |
RU (1) | RU2540018C2 (es) |
SG (1) | SG190627A1 (es) |
WO (1) | WO2009112502A1 (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
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US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
EP1460088A1 (en) | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
US8034014B2 (en) | 2007-03-06 | 2011-10-11 | Biomet Biologics, Llc | Angiogenesis initation and growth |
US20080269762A1 (en) * | 2007-04-25 | 2008-10-30 | Biomet Manufacturing Corp. | Method and device for repair of cartilage defects |
US8753690B2 (en) * | 2008-02-27 | 2014-06-17 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
EP2259774B1 (en) | 2008-02-27 | 2012-12-12 | Biomet Biologics, LLC | Methods and compositions for delivering interleukin-1 receptor antagonist |
AU2009235622C9 (en) * | 2008-03-13 | 2015-07-02 | Biotest Ag | Agent for treating disease |
JP5597553B2 (ja) * | 2008-03-13 | 2014-10-01 | バイオテスト・アクチエンゲゼルシヤフト | 疾患治療剤 |
JP2012504110A (ja) * | 2008-09-29 | 2012-02-16 | バイオテスト・アクチエンゲゼルシヤフト | 疾患治療組成物 |
US20110052561A1 (en) * | 2009-08-27 | 2011-03-03 | Biomet Biologics,LLC | Osteolysis treatment |
JP5844258B2 (ja) | 2009-08-27 | 2016-01-13 | バイオメット、バイオロジクス、リミテッド、ライアビリティー、カンパニーBiomet Biologics, Llc | インターロイキン−1受容体アンタゴニストの生産のための植込み型装置 |
GB0920944D0 (en) * | 2009-11-30 | 2010-01-13 | Biotest Ag | Agents for treating disease |
JP2013536841A (ja) | 2010-09-03 | 2013-09-26 | バイオメット、バイオロジクス、リミテッド、ライアビリティー、カンパニー | インターロイキン−1受容体アンタゴニストを送達するための方法および組成物 |
US9669071B2 (en) | 2011-03-11 | 2017-06-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for stimulating T lymphocytes with IL-2 |
CN103732241A (zh) | 2011-03-11 | 2014-04-16 | 公共事业救济局-巴黎医院 | 低剂量il-2用于治疗自身免疫相关病症或炎性病症的应用 |
US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
US9758806B2 (en) | 2013-03-15 | 2017-09-12 | Biomet Biologics, Llc | Acellular compositions for treating inflammatory disorders |
US9878011B2 (en) | 2013-03-15 | 2018-01-30 | Biomet Biologics, Llc | Treatment of inflammatory respiratory disease using biological solutions |
US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
EP3074507B1 (en) | 2013-11-26 | 2022-01-05 | Biomet Biologics, LLC | Methods of mediating macrophage phenotypes |
CA2939198A1 (en) | 2014-03-05 | 2015-09-11 | Ucb Biopharma Sprl | Multimeric fc proteins |
JP6851199B2 (ja) * | 2014-03-05 | 2021-03-31 | ユーシービー バイオファルマ エスアールエル | 多量体Fcタンパク質 |
US10441635B2 (en) | 2014-11-10 | 2019-10-15 | Biomet Biologics, Llc | Methods of treating pain using protein solutions |
AU2016225012B2 (en) * | 2015-02-27 | 2020-09-03 | Kevin Chen | Chimeric antigen receptors (CARS) targeting hematologic malignancies, compositions and methods of use thereof |
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KR102025417B1 (ko) * | 2016-02-26 | 2019-09-25 | 에스씨엠생명과학 주식회사 | 조절 t 세포 매개성 질환의 예방 또는 치료용 약학적 조성물 |
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-
2009
- 2009-03-10 BR BRPI0909179-3A patent/BRPI0909179A2/pt not_active Application Discontinuation
- 2009-03-10 CA CA2717812A patent/CA2717812A1/en not_active Abandoned
- 2009-03-10 EP EP09720958.9A patent/EP2260057B1/en active Active
- 2009-03-10 AU AU2009224690A patent/AU2009224690B2/en not_active Ceased
- 2009-03-10 MX MX2010010027A patent/MX2010010027A/es active IP Right Grant
- 2009-03-10 KR KR1020107022912A patent/KR20100135808A/ko not_active Application Discontinuation
- 2009-03-10 WO PCT/EP2009/052810 patent/WO2009112502A1/en active Application Filing
- 2009-03-10 RU RU2010141822/10A patent/RU2540018C2/ru not_active IP Right Cessation
- 2009-03-10 CN CN2009801173185A patent/CN102027018A/zh active Pending
- 2009-03-10 JP JP2010550182A patent/JP5604311B2/ja not_active Expired - Fee Related
- 2009-03-10 ES ES09720958.9T patent/ES2610327T3/es active Active
- 2009-03-10 SG SG2013034210A patent/SG190627A1/en unknown
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2010
- 2010-08-31 IL IL207892A patent/IL207892A0/en unknown
- 2010-09-13 US US12/880,768 patent/US9550831B2/en active Active
- 2010-10-11 CR CR11723A patent/CR11723A/es not_active Application Discontinuation
- 2010-10-13 CO CO10127116A patent/CO6311008A2/es not_active Application Discontinuation
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2014
- 2014-01-24 JP JP2014011246A patent/JP2014101369A/ja active Pending
Also Published As
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IL207892A0 (en) | 2010-12-30 |
ES2610327T3 (es) | 2017-04-27 |
MX2010010027A (es) | 2011-05-02 |
US9550831B2 (en) | 2017-01-24 |
RU2010141822A (ru) | 2012-04-20 |
JP2014101369A (ja) | 2014-06-05 |
US20110059083A1 (en) | 2011-03-10 |
JP2011513465A (ja) | 2011-04-28 |
AU2009224690B2 (en) | 2014-10-09 |
JP5604311B2 (ja) | 2014-10-08 |
EP2260057B1 (en) | 2016-11-23 |
RU2540018C2 (ru) | 2015-01-27 |
CN102027018A (zh) | 2011-04-20 |
AU2009224690A1 (en) | 2009-09-17 |
BRPI0909179A2 (pt) | 2015-08-25 |
SG190627A1 (en) | 2013-06-28 |
CA2717812A1 (en) | 2009-09-17 |
KR20100135808A (ko) | 2010-12-27 |
EP2260057A1 (en) | 2010-12-15 |
CR11723A (es) | 2011-06-07 |
WO2009112502A1 (en) | 2009-09-17 |
WO2009112502A9 (en) | 2010-01-07 |
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