BRPI0518869A2 - agentes citotàxicos compreendendo taxanos - Google Patents
agentes citotàxicos compreendendo taxanosInfo
- Publication number
- BRPI0518869A2 BRPI0518869A2 BRPI0518869-5A BRPI0518869A BRPI0518869A2 BR PI0518869 A2 BRPI0518869 A2 BR PI0518869A2 BR PI0518869 A BRPI0518869 A BR PI0518869A BR PI0518869 A2 BRPI0518869 A2 BR PI0518869A2
- Authority
- BR
- Brazil
- Prior art keywords
- cytotoxic agents
- taxanes
- therapeutic use
- relates
- novel cytotoxic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
AGENTES CITOTàXICOS COMPREENDENDO TAXANOS. A presente invenção refere-se a novos agentes citotóxicos e seu uso terapêutico. Mais especificamente, a invenção refere-se a novos agentes citotóxicos compreendendo taxanos e seu uso terapêutico. Estes novos agentes citotóxicos têm uso terapêutico como um resultado de liberaçpara uma específica população de células em uma maneira alvejada através de ligação química de taxano a um agente de ligação de célula.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04292898A EP1669358A1 (en) | 2004-12-07 | 2004-12-07 | Cytotoxic agents comprising new taxanes |
PCT/EP2005/014177 WO2006061258A2 (en) | 2004-12-07 | 2005-12-02 | Cytotoxic agents comprising new taxanes |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0518869A2 true BRPI0518869A2 (pt) | 2008-12-16 |
Family
ID=34931583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0518869-5A BRPI0518869A2 (pt) | 2004-12-07 | 2005-12-02 | agentes citotàxicos compreendendo taxanos |
Country Status (22)
Country | Link |
---|---|
US (1) | US7667054B2 (pt) |
EP (2) | EP1669358A1 (pt) |
JP (1) | JP2008523019A (pt) |
KR (1) | KR20070085781A (pt) |
CN (1) | CN101094857A (pt) |
AR (1) | AR054100A1 (pt) |
AU (1) | AU2005313444B2 (pt) |
BR (1) | BRPI0518869A2 (pt) |
CA (1) | CA2588587A1 (pt) |
DO (1) | DOP2005000248A (pt) |
EA (1) | EA012625B1 (pt) |
IL (1) | IL183404A0 (pt) |
MA (1) | MA29103B1 (pt) |
MX (1) | MX2007006765A (pt) |
MY (1) | MY144632A (pt) |
NO (1) | NO20073033L (pt) |
NZ (1) | NZ555406A (pt) |
PE (2) | PE20110001A1 (pt) |
TW (1) | TW200637836A (pt) |
UY (1) | UY29249A1 (pt) |
WO (1) | WO2006061258A2 (pt) |
ZA (1) | ZA200704790B (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1392359E (pt) | 2001-05-11 | 2010-01-27 | Ludwig Inst For Cancer Res Ltd | Proteínas de ligação específica e suas utilizações |
US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
EP2126127B1 (en) * | 2007-01-25 | 2016-09-28 | Dana-Farber Cancer Institute, Inc. | Use of anti-egfr antibodies in treatment of egfr mutant mediated disease |
US20080207743A1 (en) * | 2007-02-28 | 2008-08-28 | Rodger Lamb | Biologically Active Taxane Analogs and Methods of Treatment |
AU2008227123B2 (en) * | 2007-03-15 | 2014-03-27 | Ludwig Institute For Cancer Research Ltd. | Treatment method using EGFR antibodies and src inhibitors and related formulations |
CN101896503B (zh) | 2007-08-14 | 2018-05-22 | 路德维格癌症研究所有限公司 | 靶向egf受体的单克隆抗体175及其衍生物和用途 |
FR2947269B1 (fr) | 2009-06-29 | 2013-01-18 | Sanofi Aventis | Nouveaux composes anticancereux |
FR2949469A1 (fr) | 2009-08-25 | 2011-03-04 | Sanofi Aventis | Derives anticancereux, leur preparation et leur application en therapeutique |
US20110076232A1 (en) * | 2009-09-29 | 2011-03-31 | Ludwig Institute For Cancer Research | Specific binding proteins and uses thereof |
AR078471A1 (es) | 2009-10-02 | 2011-11-09 | Sanofi Aventis | COMPUESTOS MAITANSINOIDES Y EL USO DE ESTOS PARA PREPARAR CONJUGADOS CON UN ANTICUERPO LOS CUALES SE UTILIZAN COMO AGENTES ANTICANCERIGENOS Y EL PROCEDIMIENTO DE PREPARACIoN DE ESTOS CONJUGADOS |
CN101851231A (zh) * | 2010-05-27 | 2010-10-06 | 东北林业大学 | 一种多西紫杉醇新衍生物的合成方法及其在制备抗肿瘤药物中的应用 |
FR2963007B1 (fr) | 2010-07-26 | 2013-04-05 | Sanofi Aventis | Derives anticancereux, leur preparation et leur application therapeutique |
HUE048574T2 (hu) | 2012-07-12 | 2020-08-28 | Hangzhou Dac Biotech Co Ltd | Sejthez kötõdõ molekulák citotoxikus szerekkel képzett konjugátumai |
US10131682B2 (en) | 2012-11-24 | 2018-11-20 | Hangzhou Dac Biotech Co., Ltd. | Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules |
CN114262344A (zh) | 2014-02-28 | 2022-04-01 | 杭州多禧生物科技有限公司 | 带电荷链接体及其在共轭反应上的应用 |
CN104693156A (zh) * | 2014-10-22 | 2015-06-10 | 上海大学 | 9,10-二羟基-1-去氧紫杉醇类似物及其制备方法 |
CA2991973C (en) | 2015-07-12 | 2021-12-07 | Suzhou M-Conj Biotech Co., Ltd. | Bridge linkers for conjugation of a cell-binding molecule |
US9839687B2 (en) | 2015-07-15 | 2017-12-12 | Suzhou M-Conj Biotech Co., Ltd. | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule |
KR20220150408A (ko) | 2016-11-14 | 2022-11-10 | 항저우 디에이씨 바이오테크 씨오, 엘티디 | 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5703247A (en) * | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
FR2742751B1 (fr) * | 1995-12-22 | 1998-01-30 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
JP2003514903A (ja) * | 1999-11-24 | 2003-04-22 | イムノージェン インコーポレーテッド | タキサンを含有する細胞傷害薬とその治療への利用 |
US6596757B1 (en) * | 2002-05-14 | 2003-07-22 | Immunogen Inc. | Cytotoxic agents comprising polyethylene glycol-containing taxanes and their therapeutic use |
CA2494074A1 (en) * | 2002-08-02 | 2004-02-12 | Immunogen, Inc. | Cytotoxic agents containing novel potent taxanes and their therapeutic use |
-
2004
- 2004-12-07 EP EP04292898A patent/EP1669358A1/en not_active Withdrawn
-
2005
- 2005-11-29 PE PE2010000952A patent/PE20110001A1/es not_active Application Discontinuation
- 2005-11-29 PE PE2005001385A patent/PE20061060A1/es not_active Application Discontinuation
- 2005-12-01 MY MYPI20055612A patent/MY144632A/en unknown
- 2005-12-02 JP JP2007544849A patent/JP2008523019A/ja active Pending
- 2005-12-02 KR KR1020077012679A patent/KR20070085781A/ko not_active Application Discontinuation
- 2005-12-02 MX MX2007006765A patent/MX2007006765A/es active IP Right Grant
- 2005-12-02 EA EA200701251A patent/EA012625B1/ru not_active IP Right Cessation
- 2005-12-02 ZA ZA200704790A patent/ZA200704790B/xx unknown
- 2005-12-02 AU AU2005313444A patent/AU2005313444B2/en not_active Expired - Fee Related
- 2005-12-02 CA CA002588587A patent/CA2588587A1/en not_active Abandoned
- 2005-12-02 WO PCT/EP2005/014177 patent/WO2006061258A2/en active Application Filing
- 2005-12-02 CN CNA200580045888XA patent/CN101094857A/zh active Pending
- 2005-12-02 BR BRPI0518869-5A patent/BRPI0518869A2/pt not_active IP Right Cessation
- 2005-12-02 EP EP05843730A patent/EP1824858A2/en not_active Withdrawn
- 2005-12-02 NZ NZ555406A patent/NZ555406A/en not_active IP Right Cessation
- 2005-12-05 AR ARP050105077A patent/AR054100A1/es unknown
- 2005-12-06 DO DO2005P000248A patent/DOP2005000248A/es unknown
- 2005-12-06 US US11/295,294 patent/US7667054B2/en not_active Expired - Fee Related
- 2005-12-06 TW TW094142849A patent/TW200637836A/zh unknown
- 2005-12-07 UY UY29249A patent/UY29249A1/es unknown
-
2007
- 2007-05-24 IL IL183404A patent/IL183404A0/en unknown
- 2007-06-14 NO NO20073033A patent/NO20073033L/no not_active Application Discontinuation
- 2007-06-18 MA MA30008A patent/MA29103B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
KR20070085781A (ko) | 2007-08-27 |
PE20061060A1 (es) | 2006-11-14 |
EP1669358A1 (en) | 2006-06-14 |
UY29249A1 (es) | 2006-06-30 |
US20060178427A1 (en) | 2006-08-10 |
MX2007006765A (es) | 2007-08-16 |
ZA200704790B (en) | 2008-08-27 |
US7667054B2 (en) | 2010-02-23 |
WO2006061258A3 (en) | 2006-09-28 |
MA29103B1 (fr) | 2007-12-03 |
NO20073033L (no) | 2007-08-28 |
EA012625B1 (ru) | 2009-10-30 |
EP1824858A2 (en) | 2007-08-29 |
EA200701251A1 (ru) | 2007-12-28 |
AR054100A1 (es) | 2007-06-06 |
CA2588587A1 (en) | 2006-06-15 |
JP2008523019A (ja) | 2008-07-03 |
AU2005313444A1 (en) | 2006-06-15 |
TW200637836A (en) | 2006-11-01 |
DOP2005000248A (es) | 2007-02-15 |
MY144632A (en) | 2011-10-14 |
WO2006061258A2 (en) | 2006-06-15 |
AU2005313444B2 (en) | 2011-11-10 |
NZ555406A (en) | 2011-02-25 |
IL183404A0 (en) | 2007-10-31 |
CN101094857A (zh) | 2007-12-26 |
PE20110001A1 (es) | 2011-01-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 7A. ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2202 DE 19/03/2013. |