UY29249A1 - Agentes citotóxicos que comprenden taxanos nuevos - Google Patents

Agentes citotóxicos que comprenden taxanos nuevos

Info

Publication number
UY29249A1
UY29249A1 UY29249A UY29249A UY29249A1 UY 29249 A1 UY29249 A1 UY 29249A1 UY 29249 A UY29249 A UY 29249A UY 29249 A UY29249 A UY 29249A UY 29249 A1 UY29249 A1 UY 29249A1
Authority
UY
Uruguay
Prior art keywords
cytotoxic agents
taxans
therapeutic use
new
understanding new
Prior art date
Application number
UY29249A
Other languages
English (en)
Inventor
Ravi V J Chari
Commercon Alain
Michael L Miller
Baloglu Erkan
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34931583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY29249(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of UY29249A1 publication Critical patent/UY29249A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a nuevos agentes citotóxicos y su utilización terapéutica. Más específicamente, la invención se refiere a nuevos agentes citotóxicos que comprenden taxanos y su utilización terapéutica. Estos nuevos agentes citotóxicos tienen utilización terapéutica como resultado de proporcionar taxanos a una población celular específica de forma dirigida mediante enlace químico del taxano con el agente de unión a la célula.
UY29249A 2004-12-07 2005-12-07 Agentes citotóxicos que comprenden taxanos nuevos UY29249A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04292898A EP1669358A1 (en) 2004-12-07 2004-12-07 Cytotoxic agents comprising new taxanes

Publications (1)

Publication Number Publication Date
UY29249A1 true UY29249A1 (es) 2006-06-30

Family

ID=34931583

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29249A UY29249A1 (es) 2004-12-07 2005-12-07 Agentes citotóxicos que comprenden taxanos nuevos

Country Status (22)

Country Link
US (1) US7667054B2 (es)
EP (2) EP1669358A1 (es)
JP (1) JP2008523019A (es)
KR (1) KR20070085781A (es)
CN (1) CN101094857A (es)
AR (1) AR054100A1 (es)
AU (1) AU2005313444B2 (es)
BR (1) BRPI0518869A2 (es)
CA (1) CA2588587A1 (es)
DO (1) DOP2005000248A (es)
EA (1) EA012625B1 (es)
IL (1) IL183404A0 (es)
MA (1) MA29103B1 (es)
MX (1) MX2007006765A (es)
MY (1) MY144632A (es)
NO (1) NO20073033L (es)
NZ (1) NZ555406A (es)
PE (2) PE20110001A1 (es)
TW (1) TW200637836A (es)
UY (1) UY29249A1 (es)
WO (1) WO2006061258A2 (es)
ZA (1) ZA200704790B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7589180B2 (en) 2001-05-11 2009-09-15 Abbott Laboratories Inc. Specific binding proteins and uses thereof
US20100056762A1 (en) 2001-05-11 2010-03-04 Old Lloyd J Specific binding proteins and uses thereof
CN104013956B (zh) * 2007-01-25 2018-12-18 达娜-法勃肿瘤研究所公司 抗egfr抗体在治疗egfr突变体介导的疾病中的用途
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
AU2008227123B2 (en) * 2007-03-15 2014-03-27 Ludwig Institute For Cancer Research Ltd. Treatment method using EGFR antibodies and src inhibitors and related formulations
CA2696360C (en) 2007-08-14 2018-11-20 Ludwig Institute For Cancer Research Monoclonal antibody targeting the egfr receptor and uses thereof
FR2947269B1 (fr) 2009-06-29 2013-01-18 Sanofi Aventis Nouveaux composes anticancereux
FR2949469A1 (fr) 2009-08-25 2011-03-04 Sanofi Aventis Derives anticancereux, leur preparation et leur application en therapeutique
US20110076232A1 (en) * 2009-09-29 2011-03-31 Ludwig Institute For Cancer Research Specific binding proteins and uses thereof
TW201117814A (en) 2009-10-02 2011-06-01 Sanofi Aventis New maytansinoids and the use of said maytansinoids to prepare conjugates with an antibody
CN101851231A (zh) * 2010-05-27 2010-10-06 东北林业大学 一种多西紫杉醇新衍生物的合成方法及其在制备抗肿瘤药物中的应用
FR2963007B1 (fr) 2010-07-26 2013-04-05 Sanofi Aventis Derives anticancereux, leur preparation et leur application therapeutique
AU2012385228B2 (en) 2012-07-12 2016-10-06 Hangzhou Dac Biotech Co., Ltd Conjugates of cell binding molecules with cytotoxic agents
WO2014080251A1 (en) 2012-11-24 2014-05-30 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
DK3122757T3 (da) 2014-02-28 2023-10-09 Hangzhou Dac Biotech Co Ltd Ladede linkere og anvendelse deraf til konjugering
CN104693156A (zh) * 2014-10-22 2015-06-10 上海大学 9,10-二羟基-1-去氧紫杉醇类似物及其制备方法
JP6759326B2 (ja) 2015-07-12 2020-09-23 ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． 細胞結合分子の共役のための架橋連結体
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
AU2016429272A1 (en) 2016-11-14 2019-05-02 Hangzhou Dac Biotech Co., Ltd. Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
FR2742751B1 (fr) * 1995-12-22 1998-01-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
WO2001038318A1 (en) * 1999-11-24 2001-05-31 Immunogen, Inc. Cytotoxic agents comprising taxanes and their therapeutic use
US6596757B1 (en) * 2002-05-14 2003-07-22 Immunogen Inc. Cytotoxic agents comprising polyethylene glycol-containing taxanes and their therapeutic use
EP1534674A4 (en) * 2002-08-02 2007-11-28 Immunogen Inc CYTOTOXIC AGENTS CONTAINING NEW, EFFECTIVE TAXANES AND THEIR THERAPEUTIC USE

Also Published As

Publication number Publication date
PE20061060A1 (es) 2006-11-14
EP1669358A1 (en) 2006-06-14
MY144632A (en) 2011-10-14
IL183404A0 (en) 2007-10-31
KR20070085781A (ko) 2007-08-27
AR054100A1 (es) 2007-06-06
MA29103B1 (fr) 2007-12-03
EP1824858A2 (en) 2007-08-29
US20060178427A1 (en) 2006-08-10
EA012625B1 (ru) 2009-10-30
CA2588587A1 (en) 2006-06-15
DOP2005000248A (es) 2007-02-15
NZ555406A (en) 2011-02-25
WO2006061258A3 (en) 2006-09-28
ZA200704790B (en) 2008-08-27
CN101094857A (zh) 2007-12-26
PE20110001A1 (es) 2011-01-21
EA200701251A1 (ru) 2007-12-28
AU2005313444B2 (en) 2011-11-10
MX2007006765A (es) 2007-08-16
US7667054B2 (en) 2010-02-23
BRPI0518869A2 (pt) 2008-12-16
AU2005313444A1 (en) 2006-06-15
JP2008523019A (ja) 2008-07-03
NO20073033L (no) 2007-08-28
WO2006061258A2 (en) 2006-06-15
TW200637836A (en) 2006-11-01

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