DK1729732T3 - Anioniske hydrogelmatricer med pH-afhængig frigivelse som lægemiddelbærere - Google Patents

Anioniske hydrogelmatricer med pH-afhængig frigivelse som lægemiddelbærere

Info

Publication number
DK1729732T3
DK1729732T3 DK05718991T DK05718991T DK1729732T3 DK 1729732 T3 DK1729732 T3 DK 1729732T3 DK 05718991 T DK05718991 T DK 05718991T DK 05718991 T DK05718991 T DK 05718991T DK 1729732 T3 DK1729732 T3 DK 1729732T3
Authority
DK
Denmark
Prior art keywords
drug carriers
hydrogel matrices
dependent release
anionic hydrogel
matrices
Prior art date
Application number
DK05718991T
Other languages
English (en)
Inventor
Gaetano Giammona
Delia Mandracchia
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK1729732T3 publication Critical patent/DK1729732T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK05718991T 2004-04-01 2005-02-16 Anioniske hydrogelmatricer med pH-afhængig frigivelse som lægemiddelbærere DK1729732T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000168A ITRM20040168A1 (it) 2004-04-01 2004-04-01 Composizione a rilascio modificato ph dipendente.
PCT/IT2005/000081 WO2005094792A1 (en) 2004-04-01 2005-02-16 Anionic hydrogel matrices with ph dependent modified release as drug carriers

Publications (1)

Publication Number Publication Date
DK1729732T3 true DK1729732T3 (da) 2009-08-10

Family

ID=34961555

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05718991T DK1729732T3 (da) 2004-04-01 2005-02-16 Anioniske hydrogelmatricer med pH-afhængig frigivelse som lægemiddelbærere

Country Status (20)

Country Link
US (1) US20070166383A1 (da)
EP (1) EP1729732B1 (da)
JP (1) JP2007530666A (da)
KR (1) KR20060133578A (da)
CN (1) CN1913875B (da)
AT (1) ATE428405T1 (da)
AU (1) AU2005228716B2 (da)
BR (1) BRPI0509475A (da)
CA (1) CA2551797A1 (da)
CY (1) CY1109209T1 (da)
DE (1) DE602005013935D1 (da)
DK (1) DK1729732T3 (da)
ES (1) ES2325626T3 (da)
HR (1) HRP20090329T1 (da)
IT (1) ITRM20040168A1 (da)
PL (1) PL1729732T3 (da)
PT (1) PT1729732E (da)
RS (1) RS51178B (da)
SI (1) SI1729732T1 (da)
WO (1) WO2005094792A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4746883B2 (ja) * 2005-01-28 2011-08-10 リンテック株式会社 ハイドロゲル基剤、パップ剤基剤、パップ剤及び水性ゲルシート
EP2379226B1 (en) 2008-12-31 2016-04-20 3M Innovative Properties Company Live bioload detection using microparticles
JP2012513768A (ja) 2008-12-31 2012-06-21 スリーエム イノベイティブ プロパティズ カンパニー サンプリング装置及び微生物を濃縮するための方法
US9284593B2 (en) 2009-12-30 2016-03-15 3M Innovative Properties Company Live bioload detection using microparticles
US8845801B2 (en) 2009-12-30 2014-09-30 Regents Of The University Of Minnesota Bone cement and method
KR101228106B1 (ko) * 2010-01-21 2013-02-01 광주과학기술원 피부투과도, 세포유입 및 종양전달성이 증가된 나노운반체
WO2011090349A2 (ko) * 2010-01-21 2011-07-28 광주과학기술원 피부투과도, 세포유입 및 종양전달성이 증가된 나노운반체
CN103330702B (zh) * 2013-07-02 2016-03-02 江苏长泰药业有限公司 含有拟交感神经胺盐和诱导凝胶体系的医药组合物
CN108452291A (zh) * 2018-07-04 2018-08-28 西南大学 用天然丝胶蛋白治疗溃疡性结肠炎的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071508A (en) * 1975-02-11 1978-01-31 Plastomedical Sciences, Inc. Anionic hydrogels based on hydroxyalkyl acrylates and methacrylates
IT1284661B1 (it) * 1996-06-06 1998-05-21 Sigma Tau Ind Farmaceuti Uso di alcanoil l-carnitine nel trattamento terapeutico di malattie infiammatorie croniche intestinali.
DE19653631A1 (de) * 1996-12-20 1998-06-25 Basf Coatings Ag Verfahren zum Herstellen von durch Strahlung vernetzbaren polymeren Acryl- oder Methacrylsäureestern
PT986408E (pt) * 1997-06-03 2005-09-30 Innogenetics Nv Novos medicamentos baseados em polimeros compostos por gelatina modificada com metacrilamida
DE60021059T2 (de) * 1999-02-03 2006-05-18 Powderject Research Ltd. Partikuläre pharmazeutische Zusammensetzung für eine transdermale Partikelabgabe aus einem nadellosen Spritzensystem
US6547182B2 (en) * 2001-07-19 2003-04-15 Aerojet-General Corporation Solid rocket motor bolted thrust takeout structure
US7204997B2 (en) * 2002-01-29 2007-04-17 Supratek Pharma Inc. Responsive microgel and methods related thereto

Also Published As

Publication number Publication date
ATE428405T1 (de) 2009-05-15
AU2005228716A1 (en) 2005-10-13
RS51178B (sr) 2010-10-31
PL1729732T3 (pl) 2009-09-30
EP1729732A1 (en) 2006-12-13
SI1729732T1 (sl) 2009-08-31
DE602005013935D1 (de) 2009-05-28
JP2007530666A (ja) 2007-11-01
EP1729732B1 (en) 2009-04-15
PT1729732E (pt) 2009-07-02
CA2551797A1 (en) 2005-10-13
CY1109209T1 (el) 2014-07-02
AU2005228716B2 (en) 2010-07-15
KR20060133578A (ko) 2006-12-26
BRPI0509475A (pt) 2007-09-11
US20070166383A1 (en) 2007-07-19
CN1913875A (zh) 2007-02-14
HRP20090329T1 (en) 2009-09-30
ES2325626T3 (es) 2009-09-10
CN1913875B (zh) 2011-08-31
WO2005094792A1 (en) 2005-10-13
ITRM20040168A1 (it) 2004-07-01

Similar Documents

Publication Publication Date Title
DK1729732T3 (da) Anioniske hydrogelmatricer med pH-afhængig frigivelse som lægemiddelbærere
DK1792927T3 (da) Ny blokcopolymer, micelletilberedning og anticancermiddel indeholdende samme som aktiv ingrediens
EP2308870A3 (en) 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses
DOP2006000179A (es) 7-aza-indazoles sustituidos, composiciones que les contienen, procedimiento de fabricación y utilización
EA201000089A1 (ru) Применение гомо- и сополимеров для стабилизации составов активных ингредиентов
ES2156603T3 (es) Medicamentos a base de una mezcla sinergetica de metronidazol y de clindamicina.
TW200800967A (en) Benzimidazole thiophene compounds
AR052238A1 (es) Formulacion de tabletas estables
DK1863812T3 (da) Dipeptidylpeptidase-IV-inhiberende forbindelser, fremgangsmåder til fremstilling af de samme og farmaceutiske sammensætninger indeholdende de samme som aktive midler
BRPI0518869A2 (pt) agentes citotàxicos compreendendo taxanos
JO3408B1 (ar) مركبات بترين سلفون اميد ثيازول و أوكسازول
DOP2006000268A (es) Agentes antibacterianos
NO20081479L (no) 7-(2-Amino-1-hydroksyetyl)-4-hydroksybenzotiazol-2(3H)-ondenvater som beta2-adrenoceptoragonister
NO20073026L (no) 2-alkoksy-3,4,5-trihydroksy-alkylamider, fremstilling og sammensetninger derav samt anvendelse derav
NO20071871L (no) Fosfoindoler som HIV-inhibitorer.
FR2894143B1 (fr) Composition a liberation prolongee de l'actif, son procede de preparation et son utilisation.
NO20064808L (no) Orale matrixformuleringer med licarbazepin
WO2006056695A8 (fr) Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
UA100850C2 (ru) Средство для борьбы с паразитами на животных
WO2007025994A3 (fr) Utilisation d'au moins un 2-alkyle furane, a titre de principe actif depigmentant ou eclaircissant
BRPI0520821A2 (pt) formulações farmacêuticas de fenofibrato com biodisponibilidade melhorada
PA8627401A1 (es) Composiciones diuréticas de liberación prolongada
TW200633717A (en) Process for and intermediates in the preparation of canfosfamide and its salts, pharmaceutical compositions containing some intermediates, and their use as anticancer agents
TW200610526A (en) Novel hydrophilic analogs of 4,8-dihydrobenzodithiophene-4,8-diones as anticancer agents
TNSN07438A1 (en) Prolonged release formulation of active principles having a ph-dependent solubility