CO6280403A2 - Sales farmaceuticamente aceptables de (3-{[[3-(6-amino-2 butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo y su uso en terapia - Google Patents

Sales farmaceuticamente aceptables de (3-{[[3-(6-amino-2 butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo y su uso en terapia

Info

Publication number
CO6280403A2
CO6280403A2 CO10063975A CO10063975A CO6280403A2 CO 6280403 A2 CO6280403 A2 CO 6280403A2 CO 10063975 A CO10063975 A CO 10063975A CO 10063975 A CO10063975 A CO 10063975A CO 6280403 A2 CO6280403 A2 CO 6280403A2
Authority
CO
Colombia
Prior art keywords
amino
methyl
purin
oxo
therapy
Prior art date
Application number
CO10063975A
Other languages
English (en)
Spanish (es)
Inventor
Thomas Mcinally
Hakan Schulz
Original Assignee
Astrazeneca Ab
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40795767&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6280403(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab, Dainippon Sumitomo Pharma Co filed Critical Astrazeneca Ab
Publication of CO6280403A2 publication Critical patent/CO6280403A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
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    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Virology (AREA)
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  • Endocrinology (AREA)
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  • Diabetes (AREA)
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  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • AIDS & HIV (AREA)
  • Obesity (AREA)
CO10063975A 2007-12-17 2010-05-27 Sales farmaceuticamente aceptables de (3-{[[3-(6-amino-2 butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo y su uso en terapia CO6280403A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1416407P 2007-12-17 2007-12-17

Publications (1)

Publication Number Publication Date
CO6280403A2 true CO6280403A2 (es) 2011-05-20

Family

ID=40795767

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10063975A CO6280403A2 (es) 2007-12-17 2010-05-27 Sales farmaceuticamente aceptables de (3-{[[3-(6-amino-2 butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo y su uso en terapia

Country Status (26)

Country Link
US (1) US8673907B2 (fr)
EP (1) EP2235018A4 (fr)
JP (1) JP5557748B2 (fr)
KR (2) KR20160085360A (fr)
CN (1) CN101903389B (fr)
AR (1) AR069780A1 (fr)
AU (1) AU2008339095B2 (fr)
BR (1) BRPI0821020A2 (fr)
CA (1) CA2709126C (fr)
CL (1) CL2008003750A1 (fr)
CO (1) CO6280403A2 (fr)
CR (1) CR11507A (fr)
CU (1) CU23932B1 (fr)
EA (1) EA017532B1 (fr)
EC (1) ECSP10010265A (fr)
HN (1) HN2010001235A (fr)
IL (1) IL206039A0 (fr)
NI (1) NI201000104A (fr)
NZ (1) NZ585961A (fr)
PE (1) PE20091156A1 (fr)
SV (1) SV2010003596A (fr)
TW (1) TWI424848B (fr)
UA (1) UA100996C2 (fr)
UY (1) UY31531A1 (fr)
WO (1) WO2009078798A1 (fr)
ZA (1) ZA201003877B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI414525B (zh) 2004-03-26 2013-11-11 Dainippon Sumitomo Pharma Co ９-取代-８-氧基腺嘌呤化合物
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
PT2132209E (pt) 2007-03-19 2014-04-15 Astrazeneca Ab Compostos de 8-oxo-adenina substituídos na posição 9, como moduladores do recetor de tipo ¿toll¿ (tlr7)
WO2008114006A1 (fr) 2007-03-19 2008-09-25 Astrazeneca Ab Composés de 8 oxo-adenine 9 substitué comme modulateurs du récepteur de type toll (tlr7)
EP2138497A4 (fr) 2007-03-20 2012-01-04 Dainippon Sumitomo Pharma Co Nouveau composé d'adénine
PE20091236A1 (es) 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
JPWO2009091031A1 (ja) * 2008-01-17 2011-05-26 大日本住友製薬株式会社 アデニン化合物の製造方法
US8865896B2 (en) * 2008-01-17 2014-10-21 Astrazeneca Aktiebolag Method for preparing adenine compound
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