UY31427A1 - Derivados 1,2,4-triazol amino como moduladores de mglur5 - Google Patents

Derivados 1,2,4-triazol amino como moduladores de mglur5

Info

Publication number
UY31427A1
UY31427A1 UY31427A UY31427A UY31427A1 UY 31427 A1 UY31427 A1 UY 31427A1 UY 31427 A UY31427 A UY 31427A UY 31427 A UY31427 A UY 31427A UY 31427 A1 UY31427 A1 UY 31427A1
Authority
UY
Uruguay
Prior art keywords
mglur5
triazol
modulators
amino derivatives
new compounds
Prior art date
Application number
UY31427A
Other languages
English (en)
Inventor
Methvin Isaac
Andreas Wallberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of UY31427A1 publication Critical patent/UY31427A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente invencion está dirigida a nuevos compuestos, a un proceso para su preparacion, su uso en terapia y composiciones farmacéuticas que comprenden los nuevos compuestos.
UY31427A 2007-10-26 2008-10-24 Derivados 1,2,4-triazol amino como moduladores de mglur5 UY31427A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98295607P 2007-10-26 2007-10-26

Publications (1)

Publication Number Publication Date
UY31427A1 true UY31427A1 (es) 2009-05-29

Family

ID=40579779

Family Applications (1)

Application Number Title Priority Date Filing Date
UY31427A UY31427A1 (es) 2007-10-26 2008-10-24 Derivados 1,2,4-triazol amino como moduladores de mglur5

Country Status (21)

Country Link
US (1) US20090111821A1 (es)
EP (1) EP2212316A4 (es)
JP (1) JP2011500798A (es)
KR (1) KR20100089091A (es)
CN (1) CN101918399A (es)
AR (1) AR069030A1 (es)
AU (1) AU2008317544A1 (es)
BR (1) BRPI0818679A2 (es)
CA (1) CA2702974A1 (es)
CL (1) CL2008003182A1 (es)
CR (1) CR11391A (es)
DO (1) DOP2010000124A (es)
EA (1) EA201000656A1 (es)
IL (1) IL205289A0 (es)
MX (1) MX2010004362A (es)
NI (1) NI201000072A (es)
PE (1) PE20091348A1 (es)
TW (1) TW200922585A (es)
UY (1) UY31427A1 (es)
WO (1) WO2009054794A1 (es)
ZA (1) ZA201002854B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010255552A1 (en) * 2009-06-05 2012-01-12 Oslo University Hospital Hf Azole derivatives as Wtn pathway inhibitors
JP2013544874A (ja) 2010-12-08 2013-12-19 オスロ ユニヴァーシティー ホスピタル エイチエフ Ｗｎｔシグナル伝達経路阻害薬としてのトリアゾール誘導体
RU2495687C1 (ru) * 2012-06-19 2013-10-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Северо-Осетинская государственная медицинская академия" Минздравсоцразвития Российской Федерации Способ лечения больных гастроэзофагеальной рефлюксной болезнью
UA113223C2 (xx) * 2012-08-13 2016-12-26 Арилетинілпіримідини
EP2857387A1 (en) 2013-10-07 2015-04-08 Boehringer Ingelheim International Gmbh Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid
US9745308B2 (en) 2014-09-12 2017-08-29 Chiesi Farmaceutici S.P.A. Pyridazinone derivatives as phoshoinositide 3-kinases inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420355D0 (en) * 1994-10-10 1994-11-23 Univ Nottingham Preparation of protein microspheres, films and coatings
CA2230448A1 (en) * 1995-08-28 1997-03-06 Showa Yakuhin Kako Co., Ltd. Composition for local anesthesia
US5962536A (en) * 1998-07-31 1999-10-05 Komer; Gene Injectable propofol formulations
WO2005077345A1 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Compounds for the treatment of gastro-esophageal reflux disease
SG150539A1 (en) * 2004-02-18 2009-03-30 Astrazeneca Ab Tetrazole compounds and their use as metabotropic glutamate receptor antagonists
JP2007523178A (ja) * 2004-02-18 2007-08-16 アストラゼネカ アクチボラグ 代謝型グルタメート受容体アンタゴニストとしてのトリアゾール化合物およびそれらの使用
AR058807A1 (es) * 2005-09-29 2008-02-27 Astrazeneca Ab 5-(fenilisoxazoletoxi)-triazol-3-il piridinas sustituidas, para el tratamiento de trastornos mediados por el receptor mglur5
JP2009515997A (ja) * 2005-11-18 2009-04-16 タケダ サン ディエゴ インコーポレイテッド グルコキナーゼ活性剤
BRPI0709101A2 (pt) * 2006-03-24 2011-06-28 Eisai R&D Man Co Ltd derivados de triazolona e medicamento e agente terapêutico e/ou profilático compreendendo os mesmos
TW200811137A (en) * 2006-05-05 2008-03-01 Astrazeneca Ab mGluR5 modulators II
TW200811156A (en) * 2006-05-05 2008-03-01 Astrazeneca Ab mGluR5 modulators IV
TW200811179A (en) * 2006-05-05 2008-03-01 Astrazeneca Ab mGluR5 modulators VI
TW200808800A (en) * 2006-05-05 2008-02-16 Astrazeneca Ab MGluR5 modulators V
TW200811157A (en) * 2006-05-05 2008-03-01 Astrazeneca Ab mGluR5 modulators I
TW200808777A (en) * 2006-05-05 2008-02-16 Astrazeneca Ab MGLUR5 modulators III
TW200821305A (en) * 2006-10-05 2008-05-16 Astrazeneca Ab MGluR5 modulators
WO2009080663A1 (en) * 2007-12-21 2009-07-02 Merck Serono S.A. Triazole oxadiazoles derivatives
US20110039695A1 (en) * 2008-04-10 2011-02-17 Basf Se Substituted Pyridazinylmethyl Sulfonamides

Also Published As

Publication number Publication date
BRPI0818679A2 (pt) 2015-04-14
EA201000656A1 (ru) 2010-12-30
WO2009054794A1 (en) 2009-04-30
IL205289A0 (en) 2010-12-30
PE20091348A1 (es) 2009-10-04
US20090111821A1 (en) 2009-04-30
JP2011500798A (ja) 2011-01-06
AR069030A1 (es) 2009-12-23
DOP2010000124A (es) 2010-10-15
CR11391A (es) 2010-08-05
CN101918399A (zh) 2010-12-15
AU2008317544A1 (en) 2009-04-30
EP2212316A4 (en) 2012-06-27
TW200922585A (en) 2009-06-01
NI201000072A (es) 2011-03-24
CA2702974A1 (en) 2009-04-30
ZA201002854B (en) 2011-10-26
MX2010004362A (es) 2010-04-30
CL2008003182A1 (es) 2009-11-27
KR20100089091A (ko) 2010-08-11
EP2212316A1 (en) 2010-08-04

Similar Documents

Publication Publication Date Title
CR11857A (es) Compuestos pirazolicos 436
UY31481A1 (es) Nuevos derivados de pirimidina, procesos de preparacion, composiciones farmacéuticas conteniéndolos y aplicaciones
UY32203A (es) Amino pirimidinas y su uso en terapia
ECSP088884A (es) Compuestos heterociclicos fusionados y su uso como moduladores de mglur5
ECSP109903A (es) Derivados de pirazinona y su uso en el tratamiento de enfermedades pulmonares
CR11106A (es) Inhibidores de cinasa p710 s6
UY30610A1 (es) Moduladores de mglur5
UY31524A1 (es) Nuevos compuestos 010
UY30748A1 (es) Compuesto0s novedosos
UY30327A1 (es) Nuevos compuestos ii
UY30976A1 (es) Nuevos derivados de quinolina, composiciones farmaccuticas que los contienen, procesos de preparacion y aplicaciones.
UY31456A1 (es) Derivados de 2-pirazinona como inhibidores de la elastasa de los neutrofilos
UY31639A1 (es) Derivados de amida espirocíclica de fórmula i, sales farmacéuticamente aceptables, composiciones farmacéuticas conteniéndolas, procesos de preparación y aplicaciones
NI201200184A (es) Morfolinopirimidinas y su uso en terapia
UY30195A1 (es) Derivados de fenetanolamina, procedimiento de preparacion, composiciones que los contienen y aplicaciones
NI201000005A (es) Agentes citotóxicos que comprenden nuevos derivados de tomaimicina y su uso terapéutico.
ECSP099750A (es) Imidazoquinolinas con propiedades inmunomoduladoras
GT200600258A (es) Derivados de n-(piridin-2-il)-sulfonamida
UY30304A1 (es) Moduladores de mglur5 i
CR9786A (es) Compuestos de bencimidazol-tiofeno
UY30808A1 (es) Derivados de benzotiazolonas, composiciones conteniéndolos y aplicaciones
UY29818A1 (es) Nuevos compuestos de azetidina, composiciones farmaceuticas que los contienen, procesos de preparacion y sus usos terapeuticos
UY31403A1 (es) "derivados novedosos de ({((3-metilfenil)-2h-tetrazol-5-il)-etoxi} -4h-1,2,4-triazol-3-il), composiciones farmacéuticas conteniendolos y uso médico de los mismos".
UY30307A1 (es) Moduladores de mglur5 vi
UY31905A (es) Derivados de benzoxazinona, procesos de preparación, composiciones farmacéuticas conteniéndolos y aplicaciones.

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20171017