CO5140118A1 - Sales de piperidinas 4-substituidas y n-substituidas - Google Patents
Sales de piperidinas 4-substituidas y n-substituidasInfo
- Publication number
- CO5140118A1 CO5140118A1 CO99072637A CO99072637A CO5140118A1 CO 5140118 A1 CO5140118 A1 CO 5140118A1 CO 99072637 A CO99072637 A CO 99072637A CO 99072637 A CO99072637 A CO 99072637A CO 5140118 A1 CO5140118 A1 CO 5140118A1
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl
- haloalkyl
- hydrogen
- independently
- aralkyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto seleccionado de los compuestos de fórmula (I): <EMI FILE="99072637_1" ID="1" IMF=JPEG >en la que :uno de T y U es -N+R5- donde R5 es alquilo, haloalquilo, cianoalquilo, hidroxialquilo, alcoxialquilo, carboxialquilo, alcoxicarbonilalquilo, amidoalquilo, sulfonilaminoalquilo, o aralquilo y el otro es -CH-; X¯ es un anión farmacéuticamente aceptable; R1 y R2 son, independientemente uno de otro, hidrógeno o alquilo; m es un entero de 0 a 3 con la condición de que cuando T es -N+R5- entonces m es como mínimo 1; Ar y Ar1 son, independientemente uno de otro, arilo o heteroarilo; F es alquileno, alquenileno o un enlace; R es hidrógeno o alquilo; o R junto con bien R3 o R4 y los átomos a los que están unidos forman un carbociclo o un heterociclo; R3 y R4 son, independientemente uno de otro, hidrógeno, alquilo, alquenilo, haloalquilo, cicloalquilo, cicloalquilalquilo, arilo, aralquilo, heteroarilo, heteroaralquilo, heterociclilo, heterociclilalquilo, heteroalquilo, o -(alquileno)-C(O)-Z donde Z es alquilo, haloalquilo, alcoxi, haloalquiloxi, hidroxi, amino, amino mono sustituido con alquilo, heteroalquilo, haloalquilo, cicloalquilo, cicloalquilalquilo o fenilo opcionalmente sustituido independientemente con uno, dos o tres sustituyentes seleccionados de alquilo, haloalquilo, halo, nitro, ciano, -OR(donde R es hidrógeno o alquilo), -NRR´ (donde R y R´ son independientemente uno de otro hidrógeno o alquilo), -COOR (donde R es hidrógeno o alquilo) o -CONR´R" (donde R´ y R" son independientemente seleccionados de hidrógeno o alquilo); ó amino disustituido independientemente con alquilo, alquenilo, heteroalquilo, haloalquilo, cicloalquilo, cicloalquilalquilo o fenilo opcionalmente sustituido como se ha definido anteriormente; arilo, aralquilo, ariloxi, aralquiloxi, heteroarilo, heteroariloxi, o heteroaralquiloxi; E es -C(O)N(R6)-, -S02N(R6)-, -N(R7)C(0)N(R6)-, -N(R7) S02N(R6)-, N(R7)C(S)N(R6)-, -N(R7)C(0)- o -N(R7)S02- donde; R6 y R7 son, independientemente uno de otro, hidrógeno, alquilo, acilo, haloalquilo, cicloalquilo, cicloalquilalquilo, arilo, aralquilo, aralquenilo, heteroarilo, heteroaralquilo, heterocicloalquilo, heteroalquilo, o -(alquileno)-C(O)-Z, donde Z es alquilo, haloalquilo, alcoxi, haloalquiloxi, hidroxi, - 2 -amino, amino mono- o disustituido como se ha definido anteriormente, arilo, aralquilo, ariloxi, aralquiloxi, heteroarilo, heteroariloxi, o heteroaralquiloxi; Q es -CO- o una cadena de alquileno interrumpida opcionalmente por -C(O)-, -NR8, -O-, -S(O)0-2-, -C(O)N(R8)-, -N(R8)C(O)-, -N(R8)SO2-, -S02N(R8)-, -N(R9)C(O)N(R10)-, -N(R9)SO2N(R10)- o -N(R9)C(S)N(R10)- donde: R8, R9 y R10 son independientemente uno de otro, hidrógeno, alquilo, acilo, haloalquilo, cicloalquilo, cicloalquilalquilo, arilo, aralquilo, aralquenilo, heteroarilo, heteroaralquilo, heterociclilalquilo, heteroalquilo, o -(alquileno)-C(O)-Z, donde Z es alquilo, haloalquilo, alcoxi, haloalquiloxi, hidroxi, amino, amino mono- o disustituido como se ha definido anteriormente, arilo, aralquilo, ariloxi, aralquiloxi, heteroarilo, heteroariloxi, o heteroaralquiloxi;y profármacos, isómeros individuales, mezclas de isómeros y sales farmacéuticamente aceptables de los mismos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10929398P | 1998-11-20 | 1998-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5140118A1 true CO5140118A1 (es) | 2002-03-22 |
Family
ID=22326896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO99072637A CO5140118A1 (es) | 1998-11-20 | 1999-11-18 | Sales de piperidinas 4-substituidas y n-substituidas |
Country Status (20)
Country | Link |
---|---|
US (1) | US6342509B1 (es) |
EP (1) | EP1131290B1 (es) |
JP (1) | JP3421323B2 (es) |
KR (1) | KR20010081034A (es) |
CN (1) | CN1326440A (es) |
AR (1) | AR029151A1 (es) |
AT (1) | ATE386720T1 (es) |
AU (1) | AU1774600A (es) |
BR (1) | BR9915735A (es) |
CA (1) | CA2351631A1 (es) |
CO (1) | CO5140118A1 (es) |
DE (2) | DE69938193D1 (es) |
ES (1) | ES2158813B1 (es) |
FR (1) | FR2786179B1 (es) |
GB (1) | GB2343894B (es) |
IT (1) | IT1308657B1 (es) |
PE (1) | PE20001401A1 (es) |
TR (1) | TR200101397T2 (es) |
WO (1) | WO2000031033A1 (es) |
ZA (1) | ZA200103940B (es) |
Families Citing this family (28)
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ES2250132T3 (es) | 1999-05-18 | 2006-04-16 | Teijin Limited | Remedios preventivos para enfermedades asociadas a quimioquinas. |
CA2378499A1 (en) | 1999-08-04 | 2001-02-15 | Teijin Limited | Cyclic amine ccr3 antagonists |
AR028948A1 (es) | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
CA2423251A1 (en) | 2000-09-29 | 2002-04-04 | Glaxo Group Limited | Morpholin-acetamide derivatives for the treatment of inflammatory diseases |
DE60130684T2 (de) * | 2000-12-19 | 2008-08-14 | F. Hoffmann-La Roche Ag | Substituierte pyrrolidine als ccr-3-rezeptorantagonisten |
WO2002088111A1 (fr) | 2001-04-27 | 2002-11-07 | Mitsubishi Pharma Corporation | Nouveaux composes de benzylpiperidine |
GB0114699D0 (en) * | 2001-06-15 | 2001-08-08 | Novartis Ag | Organic compounds |
TW200303304A (en) | 2002-02-18 | 2003-09-01 | Astrazeneca Ab | Chemical compounds |
AU2004215679A1 (en) * | 2003-02-27 | 2004-09-10 | F. Hoffmann-La Roche Ag | CCR-3 receptor antagonists |
JP4736043B2 (ja) | 2003-03-14 | 2011-07-27 | 小野薬品工業株式会社 | 含窒素複素環誘導体およびそれらを有効成分とする薬剤 |
WO2004092169A1 (ja) | 2003-04-18 | 2004-10-28 | Ono Pharmaceutical Co., Ltd. | スピロピペリジン化合物およびその医薬用途 |
SG131946A1 (en) * | 2003-10-24 | 2007-05-28 | Hoffmann La Roche | Ccr3 receptor antagonists |
SE0400208D0 (sv) | 2004-02-02 | 2004-02-02 | Astrazeneca Ab | Chemical compounds |
ES2396419T3 (es) | 2004-09-08 | 2013-02-21 | Mitsubishi Tanabe Pharma Corporation | Compuestos de morfolina para el tratamiento de inflamaciones |
TWI400232B (zh) | 2004-09-13 | 2013-07-01 | Ono Pharmaceutical Co | 含氮雜環衍生物及以該含氮雜環衍生物為有效成分之藥劑 |
JPWO2006129679A1 (ja) | 2005-05-31 | 2009-01-08 | 小野薬品工業株式会社 | スピロピペリジン化合物およびその医薬用途 |
TW200738634A (en) * | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200734305A (en) * | 2005-08-02 | 2007-09-16 | Astrazeneca Ab | New salt III |
TW200738635A (en) * | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
EP2657235A1 (en) | 2005-10-28 | 2013-10-30 | Ono Pharmaceutical Co., Ltd. | Compound containing basic group and use thereof |
ES2407115T3 (es) | 2005-11-18 | 2013-06-11 | Ono Pharmaceutical Co., Ltd. | Compuesto que contiene un grupo básico y uso del mismo |
AU2007225836A1 (en) | 2006-03-10 | 2007-09-20 | Ono Pharmaceutical Co., Ltd. | Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient |
US8618122B2 (en) | 2006-05-16 | 2013-12-31 | Ono Pharmaceutical Co., Ltd. | Compound having acidic group which may be protected, and use thereof |
JP5245827B2 (ja) | 2006-07-31 | 2013-07-24 | 小野薬品工業株式会社 | スピロ結合した環状基を含有する化合物およびその用途 |
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WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
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TW498067B (en) | 1996-07-19 | 2002-08-11 | Hoffmann La Roche | 4-hydroxy-piperidine derivatives |
CA2261633A1 (en) | 1996-07-29 | 1998-02-05 | Banyu Pharmaceutical Co., Ltd. | Chemokine receptor antagonists |
US6136827A (en) | 1997-07-25 | 2000-10-24 | Merck & Co., Inc. | Cyclic amine modulations of chemokine receptor activity |
IL125658A0 (en) * | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
US6433165B1 (en) * | 1998-01-21 | 2002-08-13 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
CA2350903A1 (en) | 1998-11-20 | 2000-06-02 | F. Hoffmann-La Roche Ag | Pyrrolidine derivatives-ccr-3 receptor antagonists |
EP1156807A4 (en) | 1998-12-18 | 2002-04-03 | Du Pont Pharm Co | N-UREIDOALKYL-PIPERIDINES FOR USE AS MODULATORS OF THE ACTIVITY OF CHIMIOKIN RECEPTORS |
-
1999
- 1999-11-08 TR TR2001/01397T patent/TR200101397T2/xx unknown
- 1999-11-08 JP JP2000583861A patent/JP3421323B2/ja not_active Expired - Fee Related
- 1999-11-08 BR BR9915735-7A patent/BR9915735A/pt not_active IP Right Cessation
- 1999-11-08 WO PCT/EP1999/008554 patent/WO2000031033A1/en active IP Right Grant
- 1999-11-08 AT AT99960962T patent/ATE386720T1/de not_active IP Right Cessation
- 1999-11-08 AU AU17746/00A patent/AU1774600A/en not_active Abandoned
- 1999-11-08 KR KR1020017006393A patent/KR20010081034A/ko not_active Application Discontinuation
- 1999-11-08 EP EP99960962A patent/EP1131290B1/en not_active Expired - Lifetime
- 1999-11-08 CN CN99813286A patent/CN1326440A/zh active Pending
- 1999-11-08 DE DE69938193T patent/DE69938193D1/de not_active Expired - Lifetime
- 1999-11-08 CA CA002351631A patent/CA2351631A1/en not_active Abandoned
- 1999-11-16 PE PE1999001160A patent/PE20001401A1/es not_active Application Discontinuation
- 1999-11-17 GB GB9927228A patent/GB2343894B/en not_active Expired - Fee Related
- 1999-11-18 US US09/442,799 patent/US6342509B1/en not_active Expired - Fee Related
- 1999-11-18 CO CO99072637A patent/CO5140118A1/es unknown
- 1999-11-18 AR ARP990105859A patent/AR029151A1/es unknown
- 1999-11-19 FR FR9914562A patent/FR2786179B1/fr not_active Expired - Fee Related
- 1999-11-19 DE DE19955793A patent/DE19955793A1/de not_active Withdrawn
- 1999-11-19 ES ES009902546A patent/ES2158813B1/es not_active Expired - Fee Related
- 1999-11-22 IT IT1999TO001021A patent/IT1308657B1/it active
-
2001
- 2001-05-15 ZA ZA200103940A patent/ZA200103940B/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE19955793A1 (de) | 2000-05-25 |
ES2158813A1 (es) | 2001-09-01 |
ATE386720T1 (de) | 2008-03-15 |
WO2000031033A1 (en) | 2000-06-02 |
BR9915735A (pt) | 2001-09-04 |
EP1131290A1 (en) | 2001-09-12 |
IT1308657B1 (it) | 2002-01-09 |
ZA200103940B (en) | 2002-08-15 |
FR2786179A1 (fr) | 2000-05-26 |
GB2343894B (en) | 2001-07-25 |
GB9927228D0 (en) | 2000-01-12 |
JP3421323B2 (ja) | 2003-06-30 |
ITTO991021A0 (it) | 1999-11-22 |
ITTO991021A1 (it) | 2001-05-22 |
TR200101397T2 (tr) | 2001-11-21 |
FR2786179B1 (fr) | 2001-08-10 |
GB2343894A (en) | 2000-05-24 |
CN1326440A (zh) | 2001-12-12 |
JP2002530375A (ja) | 2002-09-17 |
AR029151A1 (es) | 2003-06-18 |
EP1131290B1 (en) | 2008-02-20 |
PE20001401A1 (es) | 2000-12-15 |
DE69938193D1 (de) | 2008-04-03 |
KR20010081034A (ko) | 2001-08-25 |
US6342509B1 (en) | 2002-01-29 |
ES2158813B1 (es) | 2002-03-16 |
CA2351631A1 (en) | 2000-06-02 |
AU1774600A (en) | 2000-06-13 |
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