CO4750831A1 - Procedimientos e intermedios para preparar 1-bencil-4-((5,6- dimetoxi-1-indanon)-2-il)metilpiperidina - Google Patents
Procedimientos e intermedios para preparar 1-bencil-4-((5,6- dimetoxi-1-indanon)-2-il)metilpiperidinaInfo
- Publication number
- CO4750831A1 CO4750831A1 CO96065334A CO96065334A CO4750831A1 CO 4750831 A1 CO4750831 A1 CO 4750831A1 CO 96065334 A CO96065334 A CO 96065334A CO 96065334 A CO96065334 A CO 96065334A CO 4750831 A1 CO4750831 A1 CO 4750831A1
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl
- indanon
- methylpiperidine
- compound
- dimetoxi
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US875395P | 1995-12-15 | 1995-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO4750831A1 true CO4750831A1 (es) | 1999-03-31 |
Family
ID=21733469
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO96065334A CO4750831A1 (es) | 1995-12-15 | 1996-12-12 | Procedimientos e intermedios para preparar 1-bencil-4-((5,6- dimetoxi-1-indanon)-2-il)metilpiperidina |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP0883607A1 (fr) |
JP (1) | JP3066083B2 (fr) |
KR (1) | KR20000064387A (fr) |
AP (1) | AP708A (fr) |
AR (1) | AR004368A1 (fr) |
AU (1) | AU716462B2 (fr) |
BG (1) | BG102525A (fr) |
BR (1) | BR9612018A (fr) |
CA (1) | CA2237647A1 (fr) |
CO (1) | CO4750831A1 (fr) |
CZ (1) | CZ180898A3 (fr) |
DZ (1) | DZ2141A1 (fr) |
GT (1) | GT199600092A (fr) |
HN (1) | HN1996000065A (fr) |
HR (1) | HRP960592A2 (fr) |
HU (1) | HUP9904275A3 (fr) |
IL (3) | IL136421A0 (fr) |
IS (1) | IS4752A (fr) |
MA (1) | MA24032A1 (fr) |
NO (1) | NO982712L (fr) |
NZ (1) | NZ318843A (fr) |
OA (1) | OA10694A (fr) |
PE (1) | PE25698A1 (fr) |
PL (1) | PL197306B1 (fr) |
RO (1) | RO121382B1 (fr) |
RU (1) | RU2160731C2 (fr) |
SK (1) | SK75498A3 (fr) |
TN (1) | TNSN96153A1 (fr) |
TW (1) | TW414787B (fr) |
UY (1) | UY24401A1 (fr) |
WO (1) | WO1997022584A1 (fr) |
YU (1) | YU49486B (fr) |
ZA (1) | ZA9610533B (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1047674B1 (fr) | 1998-01-16 | 2005-03-30 | Eisai Co., Ltd. | Procede de production de derive de donepezil |
IL125809A (en) | 1998-08-17 | 2005-08-31 | Finetech Lab Ltd | Process and intermediates for production of donepezil and related compounds |
US7148354B2 (en) * | 2002-07-24 | 2006-12-12 | Dr. Reddy's Laboratories Limited | Process for preparation of donepezil |
IL150982A (en) | 2002-07-30 | 2007-02-11 | Ori Lerman | Process for making Donafzil |
IL151253A0 (en) * | 2002-08-14 | 2003-04-10 | Finetech Lab Ltd | Process for production of highly pure donepezil hydrochloride |
US6953856B2 (en) | 2003-02-12 | 2005-10-11 | Usv, Limited | Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI) |
US6649765B1 (en) | 2003-02-12 | 2003-11-18 | Usv Limited, Bsd Marg. | Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL) |
WO2004082685A1 (fr) * | 2003-03-21 | 2004-09-30 | Ranbaxy Laboratories Limited | Procede de preparation de donepezil et de ses derives |
WO2004099142A1 (fr) * | 2003-05-05 | 2004-11-18 | Ranbaxy Laboratories Limited | Sel de bromhydrate de benzyl-piperidylmethyl-indanone et ses polymorphes |
AU2003247158A1 (en) | 2003-07-01 | 2005-01-21 | Hetero Drugs Limited | Preparation of intermediates for acetyl cholinesterase inhibitors |
CN1280273C (zh) * | 2003-11-05 | 2006-10-18 | 天津和美生物技术有限公司 | 合成多奈哌齐及其衍生物的方法 |
CA2581926A1 (fr) | 2004-09-29 | 2006-04-06 | Chemagis Ltd. | Utilisation de maleate de donepezil purifie pour preparer un hydrochlorure de donepezil amorphe pharmaceutiquement pur |
CN100436416C (zh) * | 2005-07-29 | 2008-11-26 | 西南合成制药股份有限公司 | 盐酸多奈哌齐合成工艺 |
GB0515803D0 (en) * | 2005-07-30 | 2005-09-07 | Pliva Hrvatska D O O | Intermediate compounds |
AR057910A1 (es) | 2005-11-18 | 2007-12-26 | Synthon Bv | Proceso para preparar donepezilo |
EP1973878B1 (fr) | 2006-01-04 | 2010-11-24 | Cipla Limited | Procede et intermediaire pour la preparation de donepezil |
CN101626688A (zh) * | 2006-12-11 | 2010-01-13 | 雷维瓦药品公司 | 茚满酮基胆碱酯酶抑制剂的组合物、合成和使用方法 |
WO2013078608A1 (fr) | 2011-11-29 | 2013-06-06 | Ziqiang Gu | Pamoate de donepezil et ses procédés de fabrication et d'utilisation |
EP3033082B1 (fr) | 2013-08-16 | 2021-06-16 | Universiteit Maastricht | Traitement d'une déficience cognitive à l'aide d'un inhibiteur de pde4 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
FR2642069B1 (fr) * | 1989-01-20 | 1991-04-12 | Rhone Poulenc Sante | Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent |
DE4439822A1 (de) * | 1994-11-08 | 1996-08-29 | Bayer Ag | Verfahren zur Herstellung von Benzyl-piperidylmethyl-indanonen |
-
1996
- 1996-10-11 NZ NZ318843A patent/NZ318843A/xx unknown
- 1996-10-11 EP EP96931937A patent/EP0883607A1/fr not_active Withdrawn
- 1996-10-11 CZ CZ981808A patent/CZ180898A3/cs unknown
- 1996-10-11 HU HU9904275A patent/HUP9904275A3/hu unknown
- 1996-10-11 IL IL13642196A patent/IL136421A0/xx unknown
- 1996-10-11 RU RU98111204/04A patent/RU2160731C2/ru not_active IP Right Cessation
- 1996-10-11 IL IL12445296A patent/IL124452A0/xx unknown
- 1996-10-11 KR KR1019980704423A patent/KR20000064387A/ko not_active Application Discontinuation
- 1996-10-11 RO RO98-01070A patent/RO121382B1/ro unknown
- 1996-10-11 CA CA002237647A patent/CA2237647A1/fr not_active Abandoned
- 1996-10-11 BR BR9612018A patent/BR9612018A/pt not_active Application Discontinuation
- 1996-10-11 SK SK754-98A patent/SK75498A3/sk unknown
- 1996-10-11 WO PCT/IB1996/001076 patent/WO1997022584A1/fr not_active Application Discontinuation
- 1996-10-11 IL IL13642096A patent/IL136420A0/xx unknown
- 1996-10-11 JP JP9522607A patent/JP3066083B2/ja not_active Expired - Lifetime
- 1996-10-11 PL PL327512A patent/PL197306B1/pl not_active IP Right Cessation
- 1996-10-11 AU AU70925/96A patent/AU716462B2/en not_active Ceased
- 1996-10-14 TW TW085112515A patent/TW414787B/zh not_active IP Right Cessation
- 1996-10-15 HN HN1996000065A patent/HN1996000065A/es unknown
- 1996-11-18 GT GT199600092A patent/GT199600092A/es unknown
- 1996-12-09 PE PE1996000883A patent/PE25698A1/es not_active Application Discontinuation
- 1996-12-10 AR ARP960105577A patent/AR004368A1/es unknown
- 1996-12-11 TN TNTNSN96153A patent/TNSN96153A1/fr unknown
- 1996-12-11 DZ DZ960186A patent/DZ2141A1/fr active
- 1996-12-11 MA MA24424A patent/MA24032A1/fr unknown
- 1996-12-11 YU YU66096A patent/YU49486B/sh unknown
- 1996-12-12 AP APAP/P/1996/000892A patent/AP708A/en active
- 1996-12-12 CO CO96065334A patent/CO4750831A1/es unknown
- 1996-12-12 UY UY24401A patent/UY24401A1/es not_active IP Right Cessation
- 1996-12-13 ZA ZA9610533A patent/ZA9610533B/xx unknown
- 1996-12-13 HR HR60/008,753A patent/HRP960592A2/xx not_active Application Discontinuation
-
1998
- 1998-05-22 IS IS4752A patent/IS4752A/is unknown
- 1998-06-05 OA OA9800076A patent/OA10694A/en unknown
- 1998-06-09 BG BG102525A patent/BG102525A/xx unknown
- 1998-06-12 NO NO982712A patent/NO982712L/no not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CO4750831A1 (es) | Procedimientos e intermedios para preparar 1-bencil-4-((5,6- dimetoxi-1-indanon)-2-il)metilpiperidina | |
BR8600428A (pt) | Compostos heterociclicos,processo para sua preparacao,composicoes inseticidas,processo para combate a insetos daninhos,utilizacao e processo para a preparacao de composicoes | |
CO4920223A1 (es) | Derivados de 1,3,8-triaza-espiro[4,5]decan-4-ona 8- sustituidos | |
NO20051600L (no) | 1,4-disubstituerte piperidinderivater og anvendelse derav som 11-betaHSD1 inhibitorer | |
ES2155995T3 (es) | Compuestos de 4-fenilpiperidina. | |
ATE238428T1 (de) | Enantioselective herstellung von pharmazeutisch aktiven sulfoxiden durch bioreduktion | |
DK0775132T3 (da) | (Azetidin-1-ylalkyl)lactamer som tachykininantagonister | |
ES2193990T3 (es) | Derivados de purina. | |
ATE72436T1 (de) | 2-(methyl(4-piperidinyl)>-1,2,3,4-tetrahydro-9h pyrido(3,4-b>indolderivate, ihre herstellung und therapeutische verwendung. | |
DE69616593D1 (de) | Phenylimidazolidine und deren verwendung als anti-androgene mittel | |
ES8703405A1 (es) | Un procedimiento para la preparacion de derivados de acetanilida | |
DE69319439D1 (de) | Propensäure derivate verwendbar als fungizide | |
ES2016017A6 (es) | Procedimiento para preparar derivados de acido 1,1-dioxocefem-4-carbotiolico. | |
ES2194709T3 (es) | Procedimiento para preparar carbamatos de tetrahidrotiopiran-o-fluorados. | |
ES2134563T3 (es) | Cianofenilsulfenil halogenuro y su utilizacion en el procedimiento de preparacion de benzoisotiazol 3-sustituido. | |
FR2737207B1 (fr) | Nouvelles n-heterocyclyl-1-aryloxyalcoyl-4-piperidinamines substituees, leur preparation et leur application en therapeutique | |
NO992870L (no) | Difenylalkyl-tetrahydropyridiner, fremgangsmåter for deres fremstilling og farmasöytiske blandinger inneholdende dem | |
SE9504008D0 (sv) | A heterocyclic chemical compound | |
GR3034656T3 (en) | Anellated dihydropyridines and their use in the production of pharmaceutical preparations | |
ES8707939A1 (es) | Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas | |
ATE182741T1 (de) | Durchwurzelungsinhibitoren | |
IT1295309B1 (it) | Procedimento per la preparazione di amminocarbonil derivati di geneserolina | |
BG60208B2 (en) | Process for preparingn-substituted 3-acyl-2-oxindole-1-carboxamides | |
TH32102A (th) | สารประกอบแนพธิล สารอินเทอมิเดียท สารผสม และวิธีใช้ | |
ECSP951529A (es) | Compuestos farmaceuticos |