CN100436416C - 盐酸多奈哌齐合成工艺 - Google Patents
盐酸多奈哌齐合成工艺 Download PDFInfo
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- CN100436416C CN100436416C CNB2005100571920A CN200510057192A CN100436416C CN 100436416 C CN100436416 C CN 100436416C CN B2005100571920 A CNB2005100571920 A CN B2005100571920A CN 200510057192 A CN200510057192 A CN 200510057192A CN 100436416 C CN100436416 C CN 100436416C
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- diethyl malonate
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Abstract
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Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB2005100571920A CN100436416C (zh) | 2005-07-29 | 2005-07-29 | 盐酸多奈哌齐合成工艺 |
Applications Claiming Priority (1)
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CNB2005100571920A CN100436416C (zh) | 2005-07-29 | 2005-07-29 | 盐酸多奈哌齐合成工艺 |
Publications (2)
Publication Number | Publication Date |
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CN1733728A CN1733728A (zh) | 2006-02-15 |
CN100436416C true CN100436416C (zh) | 2008-11-26 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CNB2005100571920A Expired - Fee Related CN100436416C (zh) | 2005-07-29 | 2005-07-29 | 盐酸多奈哌齐合成工艺 |
Country Status (1)
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CN (1) | CN100436416C (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5566004B2 (ja) * | 2007-11-14 | 2014-08-06 | 株式会社Dnpファインケミカル宇都宮 | アルコキシインダノン誘導体の製造方法 |
CN107118151A (zh) * | 2017-05-18 | 2017-09-01 | 芜湖耄智生物科技有限公司 | 用于治疗阿尔兹海默症的盐酸多奈哌齐的制备方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5100901A (en) * | 1987-06-22 | 1992-03-31 | Eisai Co., Ltd. | Cyclic amine compounds and pharmaceutical use |
WO1997022584A1 (en) * | 1995-12-15 | 1997-06-26 | Pfizer Inc. | Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine |
US6252081B1 (en) * | 1998-01-16 | 2001-06-26 | Eisai Co., Ltd. | Process for production of donepezil derivative |
US6492522B1 (en) * | 1998-08-17 | 2002-12-10 | Finetech Laboratories Ltd. | Process and intermediates for production of donepezil and related compounds |
CN1613848A (zh) * | 2003-11-05 | 2005-05-11 | 天津和美生物技术有限公司 | 合成多奈哌齐及其衍生物的新方法 |
-
2005
- 2005-07-29 CN CNB2005100571920A patent/CN100436416C/zh not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5100901A (en) * | 1987-06-22 | 1992-03-31 | Eisai Co., Ltd. | Cyclic amine compounds and pharmaceutical use |
WO1997022584A1 (en) * | 1995-12-15 | 1997-06-26 | Pfizer Inc. | Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine |
US6252081B1 (en) * | 1998-01-16 | 2001-06-26 | Eisai Co., Ltd. | Process for production of donepezil derivative |
US6492522B1 (en) * | 1998-08-17 | 2002-12-10 | Finetech Laboratories Ltd. | Process and intermediates for production of donepezil and related compounds |
CN1613848A (zh) * | 2003-11-05 | 2005-05-11 | 天津和美生物技术有限公司 | 合成多奈哌齐及其衍生物的新方法 |
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Publication number | Publication date |
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CN1733728A (zh) | 2006-02-15 |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: FANGZHENG MEDICINAL RESEARCH INSTITUTE CO., LTD. Free format text: FORMER OWNER: SOUTHWEST SYNTHETIC PHARMACEUTICAL CORP. LTD. Effective date: 20090424 |
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C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20090424 Address after: 17, middle building, No. 52 West Fourth Ring Road, Haidian District, Beijing Patentee after: PKUCare Pharmaceutical R&D Center Address before: Chongqing Town, Yubei District City Red Dragon Road No. 34 Patentee before: Southwest Synthetic Pharmaceutical Corp. Ltd. |
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C56 | Change in the name or address of the patentee | ||
CP03 | Change of name, title or address |
Address after: Room A106, Chuangxin building, 29 life road, Beijing, Changping District Patentee after: PKUCare Pharmaceutical R&D Center Address before: 17, middle building, No. 52 West Fourth Ring Road, Haidian District, Beijing Patentee before: PKUCare Pharmaceutical R&D Center |
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ASS | Succession or assignment of patent right |
Owner name: PKU INTERNATIONAL HEALTH CARE GROUP CO., LTD. |
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C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20110701 Address after: 102206 room A106, Chuangxin building, 29 life road, Changping District, Beijing Co-patentee after: PKU International Healthcare Group Co., Ltd. Patentee after: PKUCare Pharmaceutical R&D Center Address before: 102206 room A106, Chuangxin building, 29 life road, Changping District, Beijing Patentee before: PKUCare Pharmaceutical R&D Center |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20081126 Termination date: 20140729 |
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EXPY | Termination of patent right or utility model |