HN1996000065A - Procedimiento e intermedios para preparar 1 bencil - 4 - (5, 6 demetoxi - indanon) 2 - il) metilpiperidina. - Google Patents
Procedimiento e intermedios para preparar 1 bencil - 4 - (5, 6 demetoxi - indanon) 2 - il) metilpiperidina.Info
- Publication number
- HN1996000065A HN1996000065A HN1996000065A HN1996000065A HN1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A HN 1996000065 A HN1996000065 A HN 1996000065A
- Authority
- HN
- Honduras
- Prior art keywords
- demetoxi
- indanon
- methylpiperidine
- intermediates
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US875395P | 1995-12-15 | 1995-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
HN1996000065A true HN1996000065A (es) | 1997-06-26 |
Family
ID=21733469
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HN1996000065A HN1996000065A (es) | 1995-12-15 | 1996-10-15 | Procedimiento e intermedios para preparar 1 bencil - 4 - (5, 6 demetoxi - indanon) 2 - il) metilpiperidina. |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP0883607A1 (fr) |
JP (1) | JP3066083B2 (fr) |
KR (1) | KR20000064387A (fr) |
AP (1) | AP708A (fr) |
AR (1) | AR004368A1 (fr) |
AU (1) | AU716462B2 (fr) |
BG (1) | BG102525A (fr) |
BR (1) | BR9612018A (fr) |
CA (1) | CA2237647A1 (fr) |
CO (1) | CO4750831A1 (fr) |
CZ (1) | CZ180898A3 (fr) |
DZ (1) | DZ2141A1 (fr) |
GT (1) | GT199600092A (fr) |
HN (1) | HN1996000065A (fr) |
HR (1) | HRP960592A2 (fr) |
HU (1) | HUP9904275A3 (fr) |
IL (3) | IL136420A0 (fr) |
IS (1) | IS4752A (fr) |
MA (1) | MA24032A1 (fr) |
NO (1) | NO982712D0 (fr) |
NZ (1) | NZ318843A (fr) |
OA (1) | OA10694A (fr) |
PE (1) | PE25698A1 (fr) |
PL (1) | PL197306B1 (fr) |
RO (1) | RO121382B1 (fr) |
RU (1) | RU2160731C2 (fr) |
SK (1) | SK75498A3 (fr) |
TN (1) | TNSN96153A1 (fr) |
TW (1) | TW414787B (fr) |
UY (1) | UY24401A1 (fr) |
WO (1) | WO1997022584A1 (fr) |
YU (1) | YU49486B (fr) |
ZA (1) | ZA9610533B (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6252081B1 (en) | 1998-01-16 | 2001-06-26 | Eisai Co., Ltd. | Process for production of donepezil derivative |
IL125809A (en) | 1998-08-17 | 2005-08-31 | Finetech Lab Ltd | Process and intermediates for production of donepezil and related compounds |
US7148354B2 (en) * | 2002-07-24 | 2006-12-12 | Dr. Reddy's Laboratories Limited | Process for preparation of donepezil |
IL150982A (en) | 2002-07-30 | 2007-02-11 | Ori Lerman | Process for making Donafzil |
IL151253A0 (en) * | 2002-08-14 | 2003-04-10 | Finetech Lab Ltd | Process for production of highly pure donepezil hydrochloride |
US6649765B1 (en) | 2003-02-12 | 2003-11-18 | Usv Limited, Bsd Marg. | Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL) |
US6953856B2 (en) | 2003-02-12 | 2005-10-11 | Usv, Limited | Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI) |
EP1608371A1 (fr) * | 2003-03-21 | 2005-12-28 | Ranbaxy Laboratories, Ltd. | Procede de preparation de donepezil et de ses derives |
WO2004099142A1 (fr) * | 2003-05-05 | 2004-11-18 | Ranbaxy Laboratories Limited | Sel de bromhydrate de benzyl-piperidylmethyl-indanone et ses polymorphes |
WO2005003092A1 (fr) | 2003-07-01 | 2005-01-13 | Hetero Drugs Limited | Preparation d'intermediaires pour inhibiteurs de l'acetyl cholinesterase |
CN1280273C (zh) * | 2003-11-05 | 2006-10-18 | 天津和美生物技术有限公司 | 合成多奈哌齐及其衍生物的方法 |
JP2008514691A (ja) | 2004-09-29 | 2008-05-08 | ケマジス リミティド | 薬学的に純粋な非晶質塩酸ドネペジルを製造するための精製されたマレイン酸ドネペジルの使用 |
CN100436416C (zh) * | 2005-07-29 | 2008-11-26 | 西南合成制药股份有限公司 | 盐酸多奈哌齐合成工艺 |
GB0515803D0 (en) | 2005-07-30 | 2005-09-07 | Pliva Hrvatska D O O | Intermediate compounds |
AR057910A1 (es) | 2005-11-18 | 2007-12-26 | Synthon Bv | Proceso para preparar donepezilo |
WO2007077443A1 (fr) * | 2006-01-04 | 2007-07-12 | Cipla Limited | Procede et intermediaire pour la preparation de donepezil |
WO2008073452A1 (fr) | 2006-12-11 | 2008-06-19 | Reviva Pharmaceuticals, Inc. | Compositions, synthèse et procédés d'utilisation d'inhibiteurs de cholinestérase à base d'indanone |
WO2013078608A1 (fr) | 2011-11-29 | 2013-06-06 | Ziqiang Gu | Pamoate de donepezil et ses procédés de fabrication et d'utilisation |
WO2015022418A1 (fr) | 2013-08-16 | 2015-02-19 | Takeda Gmbh | Traitement d'une déficience cognitive à l'aide d'un inhibiteur de pde4 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
FR2642069B1 (fr) * | 1989-01-20 | 1991-04-12 | Rhone Poulenc Sante | Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent |
DE4439822A1 (de) * | 1994-11-08 | 1996-08-29 | Bayer Ag | Verfahren zur Herstellung von Benzyl-piperidylmethyl-indanonen |
-
1996
- 1996-10-11 SK SK754-98A patent/SK75498A3/sk unknown
- 1996-10-11 CZ CZ981808A patent/CZ180898A3/cs unknown
- 1996-10-11 IL IL13642096A patent/IL136420A0/xx unknown
- 1996-10-11 RU RU98111204/04A patent/RU2160731C2/ru not_active IP Right Cessation
- 1996-10-11 NZ NZ318843A patent/NZ318843A/xx unknown
- 1996-10-11 CA CA002237647A patent/CA2237647A1/fr not_active Abandoned
- 1996-10-11 JP JP9522607A patent/JP3066083B2/ja not_active Expired - Lifetime
- 1996-10-11 AU AU70925/96A patent/AU716462B2/en not_active Ceased
- 1996-10-11 RO RO98-01070A patent/RO121382B1/ro unknown
- 1996-10-11 HU HU9904275A patent/HUP9904275A3/hu unknown
- 1996-10-11 PL PL327512A patent/PL197306B1/pl not_active IP Right Cessation
- 1996-10-11 BR BR9612018A patent/BR9612018A/pt not_active Application Discontinuation
- 1996-10-11 IL IL12445296A patent/IL124452A0/xx unknown
- 1996-10-11 WO PCT/IB1996/001076 patent/WO1997022584A1/fr not_active Application Discontinuation
- 1996-10-11 KR KR1019980704423A patent/KR20000064387A/ko not_active Application Discontinuation
- 1996-10-11 EP EP96931937A patent/EP0883607A1/fr not_active Withdrawn
- 1996-10-11 IL IL13642196A patent/IL136421A0/xx unknown
- 1996-10-14 TW TW085112515A patent/TW414787B/zh not_active IP Right Cessation
- 1996-10-15 HN HN1996000065A patent/HN1996000065A/es unknown
- 1996-11-18 GT GT199600092A patent/GT199600092A/es unknown
- 1996-12-09 PE PE1996000883A patent/PE25698A1/es not_active Application Discontinuation
- 1996-12-10 AR ARP960105577A patent/AR004368A1/es unknown
- 1996-12-11 DZ DZ960186A patent/DZ2141A1/fr active
- 1996-12-11 YU YU66096A patent/YU49486B/sh unknown
- 1996-12-11 MA MA24424A patent/MA24032A1/fr unknown
- 1996-12-11 TN TNTNSN96153A patent/TNSN96153A1/fr unknown
- 1996-12-12 UY UY24401A patent/UY24401A1/es not_active IP Right Cessation
- 1996-12-12 CO CO96065334A patent/CO4750831A1/es unknown
- 1996-12-12 AP APAP/P/1996/000892A patent/AP708A/en active
- 1996-12-13 ZA ZA9610533A patent/ZA9610533B/xx unknown
- 1996-12-13 HR HR60/008,753A patent/HRP960592A2/xx not_active Application Discontinuation
-
1998
- 1998-05-22 IS IS4752A patent/IS4752A/is unknown
- 1998-06-05 OA OA9800076A patent/OA10694A/en unknown
- 1998-06-09 BG BG102525A patent/BG102525A/xx unknown
- 1998-06-12 NO NO982712A patent/NO982712D0/no not_active Application Discontinuation
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