CO4520281A1 - Antifungicos de tetrahidrofurano - Google Patents

Antifungicos de tetrahidrofurano

Info

Publication number
CO4520281A1
CO4520281A1 CO94057442A CO94057442A CO4520281A1 CO 4520281 A1 CO4520281 A1 CO 4520281A1 CO 94057442 A CO94057442 A CO 94057442A CO 94057442 A CO94057442 A CO 94057442A CO 4520281 A1 CO4520281 A1 CO 4520281A1
Authority
CO
Colombia
Prior art keywords
independently
antifungics
tetrahydrofuran
same
ester
Prior art date
Application number
CO94057442A
Other languages
English (en)
Inventor
K Saksena Anil
M Girijavallab Viyyor
Raymond G Lovey
Russell E Pike
Wang Haiyan
Liu Yi-Tsung
K Ganguly Ashit
Frank Bennett
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CO4520281A1 publication Critical patent/CO4520281A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Abstract

SE DESCRIBE UN COMPUESTO REPRESENTADO POR LA FOR- MULA FIGURA 1 DONDE X ES INDEPENDIENTEMENTE AMBOS F O AMBOS Cl o UN X ES INDEPENDIENTEMENTE F Y EL OTRO ES INDEPEN- DIENTEMENTE Cl: R1 ES UN GRUPO ALQUILO (C3 A C8) DE CADENA LINEAL O RAMIFICADA SUSTITUIDO POR UNO O DOS RESTOS HIDROXI, UN ETER ESTER (POR EJ., UN POLIERESTER O ESTER FOSFATO) DEL MISMO O UNA SAL FARMACEUTICAMENTE ACCEPTABLE DEL MISMO Y COMPOSI- CIONES FARMACEUTICAS DEL MISMO UTILES PARA EL TRATAMIENTO Y/O PREVENCION DE LAS INFECCIONES FUNGICAS.
CO94057442A 1993-12-21 1994-12-20 Antifungicos de tetrahidrofurano CO4520281A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17108393A 1993-12-21 1993-12-21

Publications (1)

Publication Number Publication Date
CO4520281A1 true CO4520281A1 (es) 1997-10-15

Family

ID=22622452

Family Applications (1)

Application Number Title Priority Date Filing Date
CO94057442A CO4520281A1 (es) 1993-12-21 1994-12-20 Antifungicos de tetrahidrofurano

Country Status (29)

Country Link
EP (1) EP0736030B1 (es)
JP (1) JP2834889B2 (es)
KR (1) KR0179990B1 (es)
CN (1) CN1064685C (es)
AT (1) ATE204875T1 (es)
AU (1) AU681753B2 (es)
BR (1) BR1100154B1 (es)
CA (1) CA2179396C (es)
CO (1) CO4520281A1 (es)
CZ (1) CZ294823B6 (es)
DE (2) DE122006000004I2 (es)
DK (1) DK0736030T3 (es)
ES (1) ES2159623T3 (es)
FI (1) FI118470B (es)
FR (1) FR06C0009I2 (es)
HK (1) HK1008820A1 (es)
HU (1) HU225062B1 (es)
IL (1) IL112081A (es)
LU (1) LU91216I2 (es)
MY (1) MY130217A (es)
NL (1) NL300219I2 (es)
NO (2) NO316173B1 (es)
NZ (1) NZ278713A (es)
PL (1) PL181193B1 (es)
PT (1) PT736030E (es)
SK (1) SK283035B6 (es)
TW (1) TW377349B (es)
WO (1) WO1995017407A1 (es)
ZA (1) ZA9410142B (es)

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US6147077A (en) * 1999-04-29 2000-11-14 Sepracor Inc. 2R,4S-hydroxyitraconazole isomers
US6583136B1 (en) 1999-05-04 2003-06-24 Janssen Pharmacuetica N.V. Antifungal ethers
US6362172B2 (en) 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds
JP4308902B2 (ja) * 2001-04-03 2009-08-05 シェーリング コーポレイション 増大したバイオアベイラビリティーを有する抗真菌組成物
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CN105287403A (zh) * 2014-08-02 2016-02-03 陕西合成药业股份有限公司 一种泊沙康唑前体药物的冻干组合物及其制备方法和用途
CN104370894A (zh) * 2014-10-21 2015-02-25 江苏恒盛药业有限公司 无定型泊沙康唑的制备工艺
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CN106317032A (zh) * 2015-06-15 2017-01-11 重庆圣华曦药业股份有限公司 一种制备高纯度的泊沙康唑的方法
CN106432338A (zh) * 2015-08-08 2017-02-22 陕西合成药业股份有限公司 泊沙康唑衍生物、合成和在长效制剂中的用途
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CN105949278B (zh) * 2016-03-30 2019-12-06 南京曼杰生物科技有限公司 一种取代的四氢呋喃水溶性衍生物及其应用
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TR201620462A2 (tr) 2016-12-31 2018-07-23 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ
CN106967054A (zh) * 2017-03-30 2017-07-21 成都绿林科技有限公司 一种泊沙康唑的制备方法
CN106883221A (zh) * 2017-04-17 2017-06-23 兰州大学 一种无定形泊沙康唑及其制备方法
CN108341754A (zh) * 2018-03-12 2018-07-31 扬子江药业集团有限公司 泊沙康唑杂质及其制备方法和用途
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CN112778369B (zh) * 2019-11-05 2024-01-26 华创合成制药股份有限公司 一种三唑类衍生物及其制备方法和用途
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CN114315811A (zh) * 2021-11-19 2022-04-12 江苏恒盛药业有限公司 一种三氮唑类似物化合物及其制备方法和应用

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Also Published As

Publication number Publication date
NZ278713A (en) 1997-12-19
CN1142828A (zh) 1997-02-12
WO1995017407A1 (en) 1995-06-29
AU1512795A (en) 1995-07-10
JP2834889B2 (ja) 1998-12-14
NO2006002I1 (no) 2006-02-20
AU681753B2 (en) 1997-09-04
FI118470B (fi) 2007-11-30
CZ294823B6 (cs) 2005-03-16
DE69428125T2 (de) 2002-05-02
IL112081A0 (en) 1995-03-15
HK1008820A1 (en) 1999-05-21
CA2179396C (en) 2001-04-17
ZA9410142B (en) 1996-05-02
BR1100154B1 (pt) 2013-11-26
ATE204875T1 (de) 2001-09-15
FI962577A0 (fi) 1996-06-20
LU91216I2 (en) 2006-03-27
MY130217A (en) 2007-06-29
EP0736030A1 (en) 1996-10-09
NO316173B1 (no) 2003-12-22
NL300219I2 (nl) 2006-05-01
KR0179990B1 (en) 1999-03-20
CZ180596A3 (en) 1997-01-15
SK82696A3 (en) 1997-03-05
CN1064685C (zh) 2001-04-18
NL300219I1 (nl) 2006-04-03
ES2159623T3 (es) 2001-10-16
FR06C0009I2 (es) 2006-12-29
NO962616D0 (no) 1996-06-20
NO962616L (no) 1996-08-07
IL112081A (en) 2001-08-26
HU9601709D0 (en) 1996-08-28
HUT75879A (en) 1997-05-28
PL181193B1 (pl) 2001-06-29
SK283035B6 (sk) 2003-02-04
TW377349B (en) 1999-12-21
DE69428125D1 (de) 2001-10-04
PT736030E (pt) 2002-01-30
DE122006000004I2 (de) 2007-03-29
JPH09500658A (ja) 1997-01-21
FI962577A (fi) 1996-06-20
HU225062B1 (en) 2006-05-29
CA2179396A1 (en) 1995-06-29
NO2006002I2 (no) 2011-03-07
PL315169A1 (en) 1996-10-14
FR06C0009I1 (es) 2006-05-19
DE122006000004I1 (de) 2006-04-27
DK0736030T3 (da) 2001-10-29
EP0736030B1 (en) 2001-08-29

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