CO2019007313A2 - Producción enzimática de d-alulosa - Google Patents

Producción enzimática de d-alulosa

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Publication number
CO2019007313A2
CO2019007313A2 CONC2019/0007313A CO2019007313A CO2019007313A2 CO 2019007313 A2 CO2019007313 A2 CO 2019007313A2 CO 2019007313 A CO2019007313 A CO 2019007313A CO 2019007313 A2 CO2019007313 A2 CO 2019007313A2
Authority
CO
Colombia
Prior art keywords
phosphate
allulose
alulose
enzymatic production
catalyzed
Prior art date
Application number
CONC2019/0007313A
Other languages
English (en)
Inventor
Daniel Joseph Wichelecki
Edwin O Rogers
Original Assignee
Bonumose Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62559178&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2019007313(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bonumose Llc filed Critical Bonumose Llc
Publication of CO2019007313A2 publication Critical patent/CO2019007313A2/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/24Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02Monosaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/02Monosaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/01001Phosphorylase (2.4.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/01007Sucrose phosphorylase (2.4.1.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/01008Maltose phosphorylase (2.4.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y501/00Racemaces and epimerases (5.1)
    • C12Y501/03Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y501/00Racemaces and epimerases (5.1)
    • C12Y501/03Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C12Y501/03001Ribulose-phosphate 3-epimerase (5.1.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y503/00Intramolecular oxidoreductases (5.3)
    • C12Y503/01Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01009Glucose-6-phosphate isomerase (5.3.1.9)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y504/00Intramolecular transferases (5.4)
    • C12Y504/02Phosphotransferases (phosphomutases) (5.4.2)
    • C12Y504/02002Phosphoglucomutase (5.4.2.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P2203/00Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y503/00Intramolecular oxidoreductases (5.3)
    • C12Y503/02Intramolecular oxidoreductases (5.3) interconverting keto- and enol-groups (5.3.2)
    • C12Y503/02002Oxaloacetate tautomerase (5.3.2.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

La descripción actual provee un proceso para convertir enzimáticamente un sacárido en alulosa. La invención también hace referencia a un proceso para preparar alulosa donde el proceso implica la conversión de 6-fosfato de fructosa (F6P) en 6-fosfato de alulosa (A6P), catalizada por 6-fosfato 3-epimerasa de alulosa (A6PE), y la conversión de A6P en alulosa catalizada por 6-fosfato fosfatasa de alulosa (A6PP).
CONC2019/0007313A 2016-12-14 2019-07-08 Producción enzimática de d-alulosa CO2019007313A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662434033P 2016-12-14 2016-12-14
PCT/US2017/066298 WO2018112139A1 (en) 2016-12-14 2017-12-14 Enzymatic production of d-allulose

Publications (1)

Publication Number Publication Date
CO2019007313A2 true CO2019007313A2 (es) 2019-07-31

Family

ID=62559178

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2019/0007313A CO2019007313A2 (es) 2016-12-14 2019-07-08 Producción enzimática de d-alulosa

Country Status (20)

Country Link
US (5) US11078506B2 (es)
EP (1) EP3555282A4 (es)
JP (2) JP2020513247A (es)
KR (1) KR102581107B1 (es)
CN (1) CN110088277B (es)
AU (1) AU2017376628B2 (es)
BR (1) BR112019012215A2 (es)
CA (1) CA3044894A1 (es)
CL (1) CL2019001607A1 (es)
CO (1) CO2019007313A2 (es)
IL (1) IL267250B2 (es)
MA (1) MA46152B1 (es)
MX (1) MX2019005824A (es)
MY (1) MY190907A (es)
PE (1) PE20191355A1 (es)
PH (1) PH12019501332A1 (es)
SA (1) SA519402169B1 (es)
UA (1) UA126392C2 (es)
WO (1) WO2018112139A1 (es)
ZA (1) ZA201903508B (es)

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AU2018205503A1 (en) * 2017-01-06 2019-07-25 Greenlight Biosciences, Inc. Cell-free production of sugars
AU2018310072B2 (en) * 2017-07-31 2022-03-10 Cj Cheiljedang Corporation Novel psicose-6-phosphate phosphatase, composition for producing psicose including said enzyme, method for producing psicose using said enzyme
MA54090A (fr) * 2018-10-29 2022-02-09 Bonumose Inc Production enzymatique d'hexoses
KR102233375B1 (ko) * 2018-12-11 2021-03-31 씨제이제일제당 주식회사 신규 싸이코스-6-인산의 탈인산화 효소, 이를 포함하는 싸이코스 생산용 조성물, 및 이를 이용한 싸이코스 제조방법
KR102080886B1 (ko) 2019-05-21 2020-02-24 씨제이제일제당 주식회사 부반응성이 낮은 리불로스-인산 3-에피머화 효소의 모티프 및 이를 포함하는 효소
CA3143852A1 (en) * 2019-07-17 2021-01-21 Daniel Joseph Wichelecki Immobilized enzyme compositions for the production of hexoses
CN114729345A (zh) * 2019-10-28 2022-07-08 株式会社三养社 果糖6-磷酸3-差向异构酶及其用途
US20220372535A1 (en) * 2019-10-28 2022-11-24 Samyang Corporation Fructose-6-phosphate 3-epimerase and use thereof
KR102509561B1 (ko) * 2020-12-21 2023-03-14 주식회사 삼양사 높은 기질 특이성을 갖는 탈인산화 효소 단백질 및 이의 용도
CN114790469B (zh) * 2021-01-26 2024-03-26 中国科学院天津工业生物技术研究所 一种酶促合成阿洛酮糖的方法
KR20220135401A (ko) * 2021-03-30 2022-10-07 경상국립대학교산학협력단 과당 제조용 조성물 및 제조 방법
CN113621666A (zh) * 2021-08-24 2021-11-09 山东大学 一种生物合成昆布二糖的方法
EP4433604A1 (en) * 2021-11-19 2024-09-25 Greenlight Biosciences, Inc. Compositions and methods for the production of allulose
WO2023242877A1 (en) * 2022-06-16 2023-12-21 Fertis India Pvt Ltd Enzymatic synthesis of d-allulose and its derivatives from fusion enzymes
WO2024182327A1 (en) * 2023-02-28 2024-09-06 Cargill, Incorporated Genetically modified microorganism and fermentation process for the production of d-allulose
EP4431614A1 (de) 2023-03-15 2024-09-18 Annikki GmbH Verfahren zur herstellung von wässerigen lösungen enthaltend d-psicose oder l-psicose
WO2024189214A2 (de) 2023-03-15 2024-09-19 Annikki Gmbh Verfahren zur herstellung einer wässerigen lösung enthaltend l-psicose
EP4446422A2 (de) 2023-03-15 2024-10-16 Annikki GmbH Verfahren zur herstellung einer wässerigen lösung enthaltend l-psicose

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MXPA05003334A (es) 2002-09-30 2005-07-05 Archer Daniels Midland Co Produccion libre de celulas de glucosamina.
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AU2018205503A1 (en) * 2017-01-06 2019-07-25 Greenlight Biosciences, Inc. Cell-free production of sugars

Also Published As

Publication number Publication date
PH12019501332A1 (en) 2020-02-24
AU2017376628B2 (en) 2021-04-29
US20210108241A1 (en) 2021-04-15
EP3555282A4 (en) 2020-07-22
IL267250A (en) 2019-08-29
IL267250B2 (en) 2023-06-01
US20200208187A1 (en) 2020-07-02
CA3044894A1 (en) 2018-06-21
KR102581107B1 (ko) 2023-09-21
RU2019121904A (ru) 2021-01-15
US10704069B2 (en) 2020-07-07
BR112019012215A2 (pt) 2019-11-12
US20220098632A1 (en) 2022-03-31
US20190376101A1 (en) 2019-12-12
PE20191355A1 (es) 2019-10-01
CN110088277A (zh) 2019-08-02
CL2019001607A1 (es) 2019-09-27
JP2020513247A (ja) 2020-05-14
CN110088277B (zh) 2024-10-11
JP2023052402A (ja) 2023-04-11
EP3555282A1 (en) 2019-10-23
WO2018112139A1 (en) 2018-06-21
MX2019005824A (es) 2019-08-14
MA46152B1 (fr) 2020-11-30
AU2017376628A1 (en) 2019-06-06
US20190249212A1 (en) 2019-08-15
RU2019121904A3 (es) 2021-04-30
US11168342B2 (en) 2021-11-09
MA46152A1 (fr) 2020-07-29
UA126392C2 (uk) 2022-09-28
SA519402169B1 (ar) 2023-11-16
US11053528B2 (en) 2021-07-06
KR20190094199A (ko) 2019-08-12
US11078506B2 (en) 2021-08-03
ZA201903508B (en) 2020-02-26
MY190907A (en) 2022-05-18

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